Zobrazeno 1 - 9 of 9 pro vyhledávání: '"E. H F Wong"'
1
Common discriminative stimulus properties in rats of muscarinic antagonists, clozapine and the D 3 preferring antagonist PNU-99194A: an analysis of possible mechanisms
Autor: Andrew J. Goudie, E. H F Wong, S. Haadsma-Svensson, A. J. Prus, J. A. Smith, Kjell Svensson, Lisa E. Baker, L. A. Cortes-Burgos
Publikováno v: Behavioral Pharmacology. 12:303-315
Dopamine D3 receptors have been implicated in the aetiology of schizophrenia and the actions of antipsychotic drugs. The initial studies reported here assessed the involvement of such receptors in the in vivo actions of the atypical antipsychotic clo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41d915736dfd3e93c941c5e5636929a
https://doi.org/10.1097/00008877-200109000-00001
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2
The effect of the 5-HT3 receptor antagonist, RS-42358-197, in animal models of anxiety
Autor: A.M. Domeney, M.E. Kelly, Brenda Costall, Richard M. Eglen, E. H. F. Wong, R. L. Whiting, W.L. Smith, D.M. Tomkins, Robert J. Naylor
Publikováno v: European Journal of Pharmacology. 234:91-99
The S-isomer of the novel 5-HT3 receptor antagonist RS-42358 ((S)-N-(1-azabicyclo[2.2.2]oct-3-yl)-2,4,5,6-tetrahydro-1-H- benzo[de]isoquinolin-1-one, RS-42358-197) disinhibited behaviour in the mouse suppressed by the aversive situation of the light/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7dd2b3984e01301e0ec73d2b3a8da96
https://doi.org/10.1016/0014-2999(93)90710-y
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3
Synthesis and pharmacology of (RS)-2-amino-3-(3-hydroxy-5-trifluoromethyl-4-isoxazolyl)propionic acid, a potent AMPA receptor agonist
Autor: P. Krogsgaard-Larsen, Ulf Madsen, E. H. F. Wong, Bjarke Ebert
Publikováno v: European Journal of Medicinal Chemistry. 27:479-484
Three isoxazole bioisosteres of glutamic acid derived from the specific AMPA receptor agonist ( RS )-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) were synthesized and tested electrophysiologically and in different receptor binding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8906b06b3d848a78bb4bdd0a47360a09
https://doi.org/10.1016/0223-5234(92)90181-y
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4
Sites for Antagonism on the N-Methyl-D-Aspartate Receptor Channel Complex
Autor: J. A. Kemp, E. H. F. Wong
Publikováno v: Annual Review of Pharmacology and Toxicology. 31:401-425
Interest in the physiology and pharmacology of the dicarboxylic amino acids L-glutamate and L-aspartate originally stemmed from identification of the powerful excitatory actions of these amino acids in the motor cortex by Hayashi in 1954 (1) and in t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f66be0833e48012bbb96a3243fd7e70
https://doi.org/10.1146/annurev.pa.31.040191.002153
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5
Enhancement of adenosine A1 receptor functions by benzoylthiophenes in guinea pig tissues in vitro
Autor: L. A. Flippin, E. Leung, C. S. Seran, Richard M. Eglen, E. H. F. Wong, L. K. M. Walsh, E. J. Kim, D. A. Lazar
Publikováno v: Naunyn-Schmiedeberg's archives of pharmacology. 352(2)
Previous reports on a series of benzoylthiophenes, including PD 81,723 [2-amino-4,5-dimethyl-3-(3-trifluoromethyl-benzoyl) thiophene], have shown specific enhancement of agonist binding at the adenosine A1 receptor. We have studied the effects of two
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75969c5950619d89660aa8685422d2e4
https://pubmed.ncbi.nlm.nih.gov/7477445
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6
The action of (+/-)L-660,863 [(+/-)3-(3-amino-1,2,4-oxadiazole-5-yl)-quinuclidine] at muscarinic receptor subtypes in vitro
Autor: E. H. F. Wong, A. P. D. W. Ford, Richard M. Eglen, Roger L. Whiting, G.C. Harris, J. R. Pfister
Publikováno v: Naunyn-Schmiedeberg's archives of pharmacology. 345(4)
1. The muscarinic pharmacology of a novel oxadiazole muscarinic agonist, (+/-) L-660,863, [+/-3-(3-amino-1,2,4-oxadiazole-5-yl)-quinuclidine] has been studied using pharmacological, radioligand binding and biochemical techniques, in vitro. 2. In isol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd3bf206d94df14d5d0189613104753
https://pubmed.ncbi.nlm.nih.gov/1620240
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9
Biochemical Properties of the GABA/Barbiturate/Benzodiazepine Receptor-Chloride Ion Channel Complex
Autor: Ronnie G. King, G. B. Stauber, R. W. Olsen, E. H. F. Wong, D. Murakami, J. B. Fischer
Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781468448078
The inhibitory neurotransmitter γ-aminobutyric acid (GABA) acts by increasing chloride permeability in the postsynaptic cell membrane. Chloride ion channels are regulated via GABA binding to its receptor. The cellular response to GABA has been shown
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fb625faabe2f4b8cdd53d524bf6a0ad
https://doi.org/10.1007/978-1-4684-4805-4_17
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