Zobrazeno 1 - 10
of 34
pro vyhledávání: '"E. Gregory MacEwen"'
Autor:
Douglas H. Thamm, Nasim Akhtar, Stuart C. Helfand, Robert Auerbach, Erin B. Dickerson, E. Gregory MacEwen, Rachel L. Lewis
Publikováno v:
Research in Veterinary Science. 81:76-86
Canine hemangiosarcoma (HSA) is a devastating disease. Investigation of novel therapies has been limited by the limited availability of canine HSA-derived cell lines. We report the development of a canine HSA-derived cell line, DEN-HSA, which recapit
Autor:
Richard R. Dubielzig, David M. Vail, Ivan King, Ilene D. Kurzman, Mario Sznol, Douglas H. Thamm, Zujin Li, E. Gregory MacEwen
Publikováno v:
Clinical Cancer Research. 11:4827-4834
Purpose: Genetically modified bacteria are a potentially powerful anticancer therapy due to their tumor targeting capacity, inherent antitumor activity, and ability to serve as efficient vectors for gene delivery. This study sought to characterize th
Autor:
Douglas H. Thamm, Jon Kutzke, Rachel Tsan, Robert Radinsky, Julie A Schmidt, Josep Pastor, Jennifer S. Carew, E. Gregory MacEwen
Publikováno v:
Clinical and Experimental Metastasis. 20:421-430
To further characterize the role of hepatocyte growth factor-scatter factor (HGF-SF) and its receptor (c-Met) in osteosarcoma (OS), human OS cell lines with low (SAOS-2) and high (SAOS-LM2) metastatic potential, and cell lines derived from spontaneou
Autor:
Brenda Phillips, David M. Vail, A. Elizabeth Hershey, George R. Pettit, Kristine M. Burgess, E. Gregory MacEwen, Douglas H. Thamm
Publikováno v:
Cancer Chemotherapy and Pharmacology. 49:251-255
Purpose: To evaluate the short-term adverse effects of administration of dolastatin-10 (Dol-10) to dogs with spontaneously occurring malignant tumors. Methods: A total of 34 tumor-bearing dogs were given Dol-10 as a rapid intravenous bolus every 14 d
Autor:
Ruthanne Chun, Ilene D. Kurzman, C. Guillermo Couto, Jeff Klausner, Carolyn Henry, E. Gregory MacEwen
Publikováno v:
Journal of Veterinary Internal Medicine. 14:495-498
Publikováno v:
Cancer Biotherapy. 9:113-122
Liposome-muramyl tripeptide-phosphatidylethanolamine (L-MTP-PE) has been shown to activate monocytes in vivo to become tumoricidal resulting in reduction in metastasis as well as prolongation of survival time in murine and canine tumor models. Granul
Autor:
E. Gregory MacEwen
Publikováno v:
Veterinary Clinics of North America: Small Animal Practice. 20:1055-1073
The major shift today has been away from nonspecific compounds acting on immune mechanisms to using biologics which have specific, defined roles in acting on the immune response. The field of biologic response modification is progressing very rapidly