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Hepatitis B virus reactivation among hepatitis C patients treated with direct-acting antiviral therapies in routine clinical practice

Autor: Mario Minichiello, A. Scuteri, Elisabetta Loggi, Fabio Conti, E. Grandini, Giovanni Vitale, Giuliano Furlini, Roberto Di Donato, Silvia Galli, Pietro Andreone, Carmela Cursaro, Stefano Gitto

Publikováno v: Journal of Clinical Virology. 93:66-70

Background Hepatitis B (HBV) reactivation in chronic hepatitis C (CHC) patients treated with IFN-free direct acting antiviral (DAA) therapies has recently emerged as a potential risk. Given the potential burden of this issue, further data are needed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c14020942e8e672801b69d20106428
https://doi.org/10.1016/j.jcv.2017.05.021

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Vitamin E for the treatment of E-antigen-positive chronic hepatitis B in paediatric patients: results of a randomized phase 2 controlled study

Autor: Lorenzo Badia, C. Puggioli, Pietro Andreone, Michele Pavoni, Pierluigi Viale, Silvia Galli, Maria Letizia Bacchi Reggiani, Ranka Vukotic, Donatella Comparcola, E. Grandini, Carmela Cursaro, Sirio Fiorino, Elisabetta Loggi, Mauro Bernardi, Silvia Maselli, Gabriella Verucchi

Publikováno v: Liver International. 37:54-61

Background & aims The treatment of chronic hepatitis B infection (CHB) in children is still an area of great uncertainty. Vitamin E is an immunostimulating/antioxidant compound proven to be safe and effective for the treatment of adult CHB. The aim o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d799e4b7cfc3d59d0ce585175e74a45c
https://doi.org/10.1111/liv.13192

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Worsening of Serum Lipid Profile after Direct Acting Antiviral Treatment

Autor: A. Scuteri, Claudio Borghi, E. Grandini, Giovanni Vitale, Valeria Guarneri, Arrigo F G Cicero, Fabio Conti, Pietro Andreone, Stefano Gitto, Carmela Cursaro, Marina Giovannini, Elisabetta Loggi

Publikováno v: Annals of Hepatology, Vol 17, Iss 1, Pp 64-75 (2018)

Introduction. Host lipid metabolism influences viral replication and lifecycle of hepatitis C virus. Our aim was to evaluate changes in glucose and lipid metabolism of patients with chronic hepatitis C after therapy with direct acting antivirals (DAA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bce0d3a2825975aef8fc46a85aa30d6
http://hdl.handle.net/11585/622359

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Immunological modifications during treatment with thymosin α1 plus antiviral therapy in chronic hepatitis C

Autor: Annagiulia Gramenzi, A. Riili, Mauro Bernardi, E. Grandini, F. Cannoletta, C. Fortini, Elisabetta Loggi, R. Di Donato, A. Scuteri, P. Andreone, Carmela Cursaro

Publikováno v: Annals of the New York Academy of Sciences. 1194:147-152

The current standard therapy for the treatment of chronic hepatitis C virus (HCV) is the combination of peginterferon and ribavirin, although many patients fail to clear the virus and their retreatment options are still unsatisfactory. Thymosin alpha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55fabc45422829dfc93f02d724780ca2
https://doi.org/10.1111/j.1749-6632.2010.05461.x

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In vitro effect of thymosin-alpha1 and interferon-alpha on Th1 and Th2 cytokine synthesis in patients with eAg-negative chronic hepatitis B

Autor: E. Grandini, Ranka Vukotic, Elisabetta Loggi, Silvia Galli, Mauro Bernardi, A. Scuteri, Marzia Margotti, Annagiulia Gramenzi, Giovanni Vitale, Carmela Cursaro, Pietro Andreone

Publikováno v: Journal of Viral Hepatitis. 15:442-448

Thymosin alpha-1 (Talpha1) has been shown to be effective in chronic hepatitis B treatment. This study investigated the effect of Talpha1 and interferon-alpha (IFNalpha) on cytokine production by peripheral blood mononuclear cells (PBMCs) of 12 patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c45620684686076a926362568b2fa78
https://doi.org/10.1111/j.1365-2893.2007.00960.x

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Deregulation of microRNA expression in peripheral blood mononuclear cells from patients with HCV-related malignancies

Autor: Alessia Piluso, Cristina Stasi, Pietro Andreone, Fabio Conti, Elisa Fognani, Monica Monti, Elisabetta Loggi, Laura Gragnani, Anna Linda Zignego, Marzia Margotti, E. Grandini

Background and aim: Hepatocellular carcinoma is one of the major causes of death due to cancer worldwide, and its association with hepatitis C virus infection has been definitively established. Hepatitis C virus is also involved in the pathogenesis o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6ba8bf02b4aa940f7a44657b395367
http://hdl.handle.net/2158/1084551

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Patterns of HCV-RNA and HCV core antigen in the early monitoring of standard treatment for chronic hepatitis C

Autor: Giuliano Furlini, Mauro Bernardi, Elisabetta Loggi, Silvia Galli, Pietro Andreone, A. Scuteri, E. Grandini, Carmela Cursaro, Claudio Galli, Arianna Martello Panno

Background An early drop of HCV-RNA levels is useful in assessing response to antiviral treatment in chronic hepatitis C; the first recommended time point is 4 weeks after the start of therapy. Objectives We evaluated retrospectively HCV-RNA and HCVA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d112d9ecd3af07c97c55dc6c7ebede6e
http://hdl.handle.net/11585/133622

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Stem cells for end stage liver disease: How far have we got?

Autor: Mauro Bernardi, Stefania Lorenzini, E. Grandini, Pietro Andreone, Stefano Gitto

End stage liver disease (ESLD) is a health problem worldwide. Liver transplantation is currently the only effective therapy, but its many drawbacks include a shortage of donors, operative damage, risk of rejection and in some cases recidivism of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0035b1f3e753ba2358665a95ba496499
https://europepmc.org/articles/PMC2738783/

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