Zobrazeno 1 - 10
of 194
pro vyhledávání: '"E. Gadd"'
Autor:
Yan Luo, Martha E. Gadd, Yaqing Qie, Andrea Otamendi-Lopez, Jesus E. Sanchez-Garavito, Mieu M. Brooks, Maria J. Ulloa Navas, Tanya Hundal, Shuhua Li, Vanessa K. Jones, Yanyan Lou, Tushar Patel, Roxana Dronca, Mohamed A. Kharfan-Dabaja, Haidong Dong, Alfredo Quinones-Hinojosa, Hong Qin
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200891- (2024)
Chimeric antigen receptor (CAR) T cell therapy has encountered limited success in solid tumors. The lack of dependable antigens and the immunosuppressive tumor microenvironment (TME) are major challenges. Within the TME, tumor cells along with immuno
Externí odkaz:
https://doaj.org/article/eba59695e4f1498cac886149059c76a1
Autor:
Yaqing Qie, Martha E. Gadd, Qing Shao, Tommy To, Andrew Liu, Shuhua Li, Rocio Rivera‐Valentin, Farah Yassine, Hemant S. Murthy, Roxana Dronca, Mohamed A. Kharfan‐Dabaja, Hong Qin, Yan Luo
Publikováno v:
MedComm, Vol 5, Iss 9, Pp n/a-n/a (2024)
Abstract The challenge of disease relapsed/refractory (R/R) remains a therapeutic hurdle in chimeric antigen receptor (CAR) T‐cell therapy, especially for hematological diseases, with chronic lymphocytic leukemia (CLL) being particularly resistant
Externí odkaz:
https://doaj.org/article/2f29030e86d846d6bad6c794841fdd0f
Autor:
Kathleen E. Hupfeld, Jessica K. Lee, Nichole E. Gadd, Igor S. Kofman, Yiri E. De Dios, Jacob J. Bloomberg, Ajitkumar P. Mulavara, Rachael D. Seidler
Publikováno v:
Frontiers in Systems Neuroscience, Vol 13 (2020)
Astronauts return to Earth from spaceflight missions with impaired mobility and balance; recovery can last weeks postflight. This is due in large part to the altered vestibular signaling and sensory reweighting that occurs in microgravity. The neural
Externí odkaz:
https://doaj.org/article/83b04955f2b74586a2c520c7d5ab1c8c
Publikováno v:
Expert opinion on investigational drugs. 31(2)
Long-term outcome of patients with acute myeloid leukemia (AML) remains dismal, especially for those with high-risk disease or who are refractory to conventional therapy. CAR T-cell therapy provides unique opportunity to improve outcome by specifical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77b84cb08f8c37c6b2377aba992e456
https://pubmed.ncbi.nlm.nih.gov/35051347
https://pubmed.ncbi.nlm.nih.gov/35051347
Autor:
Yenny M, Vanegas, Razan, Mohty, Martha E, Gadd, Yan, Luo, Mahmoud, Aljurf, Hong, Qin, Mohamed A, Kharfan-Dabaja
Publikováno v:
Hematology/Oncology and Stem Cell Therapy. 15
Chimeric antigen receptors (CARs) are synthetic engineered receptors with an antigen recognition domain derived from a high-specificity monoclonal antibody that can target surface molecules on tumor cells. T cells are genetically engineered to expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa1138219c3a9e9cf735adaa7f78cbc
https://doi.org/10.56875/2589-0646.1026
https://doi.org/10.56875/2589-0646.1026
Autor:
Vincent eKoppelmans, Ajitkumar P Mulavara, Peng eYuan, Kaitlin E Cassady, Katherine A Cooke, Scott J Wood, Patricia A Reuter-Lorenz, Yiri E De Dios, Vahagn eStepanyan, Darcy L Szecsy, Nichole E Gadd, Igor eKofman, Jessica M Scott, Meghan E Downs, Jacob J Bloomberg, Lori ePloutz-Snyder, Rachael D Seidler
Publikováno v:
Frontiers in Systems Neuroscience, Vol 9 (2015)
BACKGROUND Spaceflight has been associated with changes in gait and balance; it is unclear whether it affects cognition. Head down tilt bed rest (HDBR) is a microgravity analog that mimics cephalad fluid shifts and body unloading. In consideration of
Externí odkaz:
https://doaj.org/article/ff2d3833ed0846f3ada79a2878559e46
Publikováno v:
Transplantation and cellular therapy. 28(1)
Chronic lymphocytic leukemia (CLL) is the most prevalent leukemia in the Western hemisphere. The recent availability of novel targeted therapies, namely Bruton's tyrosine kinase, phosphoinositide-3 kinase, and BCL-2 inhibitors, have revolutionized th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9888bed23b6ce8fb82bf79f6e1cd39c
https://pubmed.ncbi.nlm.nih.gov/34656807
https://pubmed.ncbi.nlm.nih.gov/34656807
Autor:
Yan Luo, Kaihin Lui, Tommy T. To, Andrew liu, Farah Yassine, Mohamed A. Kharfan Dabaja, Martha E. Gadd, Hong Qin
Publikováno v:
Cancer Research. 82:2855-2855
B-cell chronic lymphocytic leukemia (B-CLL) is the most common leukemia in adults with CD19-targeting CAR T-cell therapy showing an excellent initial curative response. However, 10-20% of patients who receive anti-C19 CAR T-cell treatment experience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47140ae114a1eb59eb8e2d5ec0637e04
https://doi.org/10.1158/1538-7445.am2022-2855
https://doi.org/10.1158/1538-7445.am2022-2855
Akademický článek
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Autor:
Kathleen E, Hupfeld, Jessica K, Lee, Nichole E, Gadd, Igor S, Kofman, Yiri E, De Dios, Jacob J, Bloomberg, Ajitkumar P, Mulavara, Rachael D, Seidler
Publikováno v:
Frontiers in Systems Neuroscience
Astronauts return to Earth from spaceflight missions with impaired mobility and balance; recovery can last weeks postflight. This is due in large part to the altered vestibular signaling and sensory reweighting that occurs in microgravity. The neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f63f3eca0cfa37278dbd4f5896c7d73c
https://pubmed.ncbi.nlm.nih.gov/31998084
https://pubmed.ncbi.nlm.nih.gov/31998084