Zobrazeno 1 - 10
of 225
pro vyhledávání: '"E. GIAVINI"'
Autor:
A. Guglielmotti, C. Devastato, Carla Landolfi, S. Tongiani, D. La Porta, A. Campana, A. Nyska, E. Giavini, L. Durando
Publikováno v:
Toxicology Letters. 238:S263-S264
Publikováno v:
Toxicological Sciences. 20:437-445
Autor:
Ahmad M. Mansour, Taiji Sakamoto, Paul Henkind, Kazunari Tanaka, E. Giavini, Ryo Suzuki, Seiji Hayasaka, Hajime Inomata, G.D. Roversi, Tomoichi Setogawa, Sayuri Ugomori, Joseph B. Walsh, Akihiko Tawara, Shinji Kurimoto, Kei-ichi Morihiro, Tatsuo Kodama, Hitomi Shibasaki, Markku Leinonen, Norio Fujiwara, Valter Elenius
Publikováno v:
Ophthalmologica. 204:I-IV
Publikováno v:
Teratology. 59(2)
The antiepileptic drug valproic acid is a well-known teratogenic agent; its main target organ is the neural tube, though skeletal malformations have also been described. In our recent work, respecifications of vertebrae were described in rat fetuses
Publikováno v:
Teratogenesis, carcinogenesis, and mutagenesis. 16(2)
This experiment was carried out with the aims of comparing the embryotoxic potential of valproic acid (VPA) in rats and mice, better defining the malformation pattern in these species, and comparing the embryotoxic effects detectable in mid-pregnancy
Publikováno v:
Annali dell'Istituto superiore di sanita. 29(1)
During the last decade there has been a tremendous increase in publications describing methods for in vitro toxicological research and emphasizing their advantages, suitability and necessity, rather than the classical in vivo studies. In this review
Autor:
E, Giavini
Publikováno v:
Annali dell'Istituto superiore di sanita. 29(1)
Substantial literature indicates that diabetes in pregnant rats and mice induces embryo lethality, growth retardation, and a variable incidence of birth defects. All these embryopathic effects appear to be mediated by several factors, e.g. genetic di
Autor:
E. Giavini, G.D. Roversi
Publikováno v:
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde. 204(4)
Congenital cataract occurs in 90-95% of diabetic rat fetuses. The pathogenetic mechanism is triggered by fetal hyperglycemia and presents the following steps: (1) a high glucose concentration in the lens; (2) reduction of glucose to sorbitol by aldos
Autor:
E, Giavini
Publikováno v:
Toxicology in Vitro. 9:v
Autor:
E. Giavini, F. Ornaghi
Publikováno v:
Mutation Research Letters. 225:71-74
To test the capability of different chemicals to induce clastogenic effects in pre-implantation embryos in vivo, rat blastocysts were collected on the afternoon of the 4th day of gestation from the uterus of females treated on the morning of the 3rd