Zobrazeno 1 - 10 of 29 pro vyhledávání: '"E. G. Shephard"'
1
Pentraxin binding to isolated rat liver nuclei
Autor: F C de Beer, E G Shephard, S Coetzee, A F Strachan, P J Smith
Publikováno v: Biochemical Journal. 279:257-262
The interaction of human C-reactive protein (CRP) and serum amyloid P-component (SAP) with isolated rat liver nuclei was studied to identify nuclear ligands for each pentraxin using the iodinatable heterobifunctional thiol-cleavable cross-linking rea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd9bd5b2fc3774b6c7e8e5870b085e7
https://doi.org/10.1042/bj2790257
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2
Degradation of fibronectin in association with vascular endothelial disruption in preeclampsia
Autor: C A, de Jager, E G, Shephard, S C, Robson, K, Jaskiewicz, S, Froese, J, Anthony, R E, Kirsch
Publikováno v: The Journal of laboratory and clinical medicine. 125(4)
The objectives of this study were (1) To assess human umbilical cord vein endothelial cell (HUVEC) fibronectin (Fn) content and integrity in patients with preeclampsia and (2) to investigate the ability of Fn and Fn fragments (FnDP) to disrupt endoth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71913bf9902d2b914311bc1321d92988
https://pubmed.ncbi.nlm.nih.gov/7706909
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6
Characterization of neutrophil-mediated degradation of human C-reactive protein and identification of the protease
Autor: Mati Fridkin, E. G. Shephard, S. L. Kelly, Ronald Anderson
Publikováno v: Clinical and experimental immunology. 87(3)
SUMMARY Human C-reactive protein (CRP) is shown to mediate a release of enzymatic activity from neutrophils which promotes its own degradation in the extracellular medium. This egress of proteolytic activity, which was upregulated by phorbol 12-myris
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecef620b6568f5e6b7cc5ccdb255aba
https://pubmed.ncbi.nlm.nih.gov/1544236
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9
Biosynthesis and Processing of SAA by Mouse L-Cells Transfected with the Human SAAg9 Gene
Autor: F C de Beer, A. F. Strachan, E G Shephard, I. P. Fraser, G. A. Coetzee, D R van der Westhuyzen
Publikováno v: Amyloid and Amyloidosis 1990 ISBN: 9789401054508
Pulse-chase studies of SAA biosynthesis and processing in mouse L-cells transfected with the SAAg9 gene have shown that, over a 2h time period, intracellular SAA does not show amino-terminal trimming. Extracellular SAA, although principally composed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::085160bff291edc1901d3b9b4af91ba3
https://doi.org/10.1007/978-94-011-3284-8_11
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10
Peptides generated from C-reactive protein by a neutrophil membrane protease. Amino acid sequence and effects of peptides on neutrophil oxidative metabolism and chemotaxis
Autor: E G, Shephard, R, Anderson, O, Rosen, M S, Myer, M, Fridkin, A F, Strachan, F C, De Beer
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 145(5)
We have recently provided evidence that C-reactive protein (CRP) could act as an up-regulatable substrate for membrane-associated neutrophil serine protease(s). The resultant degradation of CRP yielded small soluble bioactive peptides that inhibit ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e63150e231e2162a1a2d10cfedee282
https://pubmed.ncbi.nlm.nih.gov/2166760
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