Zobrazeno 1 - 3
of 3
pro vyhledávání: '"E. G. Golovnya"'
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 48-53 (2020)
In children oncology high doses of methotrexate (HD Mtx) use for treatment of osteosarcoma, acute lymphoblastic leukemia and many others tumors. Due to high intra- and interindividual Mtx pharmacokinetic variability it is essential perform monitoring
Externí odkaz:
https://doaj.org/article/456d745a65a149bcad6817afc6e985c8
Publikováno v:
Успехи молекулярной онкологии, Vol 2, Iss 1, Pp 082-089 (2015)
Methotrexate (Mtx) is a cytotoxic drug from the group of antimetabolites, folic acid antagonists. High-dose (HD) Mtx in pediatric oncology are used for the treatment of osteosarcoma (OS), and other types of tumors. This therapy has allowed to achieve
Externí odkaz:
https://doaj.org/article/8fab9aa7a80b4812b1fef5b9c115a7f7
Publikováno v:
Klinicheskaia laboratornaia diagnostika. 67(1)
The data on the diagnostic levels of sepsis markers in blood plasma in 117 patients with oncological diseases at the age from 1 to 18 years are presented. The patients were divided into 4 groups depending on the outcome of the clinical course of the