Zobrazeno 1 - 10
of 354
pro vyhledávání: '"E. Frindel"'
Publikováno v:
Leukemia. 6(10)
AcSDKP (inhibitor of entry into cycle of pluripotent hemopoietic stem cells) is able to decrease mixed lymphocyte reaction intensity when H-2 incompatible allogeneic spleen cells are used as stimulators. This is a first approach to determining whethe
Publikováno v:
Leukemia. 6(10)
AcSDKP is a physiological negative regulator of hematopoietic stem cell proliferation. To investigate the applicability of AcSDKP in the prevention of graft-versus-host disease, this tetrapeptide was tested in mice and showed an inhibitory effect on
Publikováno v:
Experimental hematology. 20(7)
The biological activity of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) on hemopoietic cell binding to the stromal cells was studied by using a rosette formation technique that quantitatively represents the specific hemopoietic cell binding to
Publikováno v:
Leukemia. 6(6)
A decrease of endogenous acetyl-ser-asp-lys-pro (AcSDKP) levels in murine plasma was observed after Ara-C treatment. This decrease preceded the entry of pluripotent hemopoietic stem cells (CFU-S) into the cell cycle. This suggests a correlation betwe
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 315(12)
The intra and extracellular kinetics of AcSDKP levels in cell culture have been studied. A close correlation was observed between the minimal level of intracellular AcSDKP (a negative regulator of cell proliferation) and the initiation of DNA synthes
Publikováno v:
Leukemia. 5(3)
In 1977, Frindel et al. reported the presence in fetal calf bone marrow of a low molecular factor, the tetrapeptide Ac-N-Ser-Asp-Lys-Pro (AcSDKP), capable of inhibiting in vivo the hematopoietic pluripotent stem cell (CFU-S) recruitment into DNA synt
Study of an inhibiting factor of epidermal proliferation in plucked skin and various tumours of mice
Publikováno v:
British Journal of Dermatology. 95:131-135
SUMMARY The aim of our research was to investigate, by autoradiographic meAods, the presence of an inhibitory factor (IF) in normal skin, in plucked skin and in five experimental skin tumours of the mouse, capable of inhibiting epidermal proliferatio
Autor:
F. Sainteny, E. Frindel
Publikováno v:
Leukemia Research. 2:181-185
The number of bone marrow CFU-S decreases at the terminal stage of spontaneous AKR leukemia. This decrease is compensated by an increase of CFU-S in the spleen, lymph nodes, liver and thymus. Thus, the overall CFU-S number is basically equivalent to
Publikováno v:
Cell Proliferation. 2:51-65
The cell cycles of an experimental ascitic tumour of the C3H mouse (NCTC 2472) were determined at various times after the intraperitoneal injection of 106 cells. It was found that, contrary to results in solid NCTC 2472 tumours, obtained with the sam
Publikováno v:
Cell Proliferation. 4:423-431
The number of nucleated bone marrow cells, the number of CFU and the number of DNA-synthesizing cells in the mouse were studied after injection of hydroxyurea. It was found that one injection provokes a partial synchronization of surviving cells and