Zobrazeno 1 - 10
of 4 374
pro vyhledávání: '"E. Fox"'
Autor:
Jeremy W. Cannon, Danielle S. Gruen, Ruben Zamora, Noah Brostoff, Kelly Hurst, John H. Harn, Fayten El-Dehaibi, Zhi Geng, Rami Namas, Jason L. Sperry, John B. Holcomb, Bryan A. Cotton, Jason J. Nam, Samantha Underwood, Martin A. Schreiber, Kevin K. Chung, Andriy I. Batchinsky, Leopoldo C. Cancio, Andrew J. Benjamin, Erin E. Fox, Steven C. Chang, Andrew P. Cap, Yoram Vodovotz
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background Optimizing resuscitation to reduce inflammation and organ dysfunction following human trauma-associated hemorrhagic shock is a major clinical hurdle. This is limited by the short duration of pre-clinical studies and the sparsity o
Externí odkaz:
https://doaj.org/article/4ec280b49b694ff292ab1c9cd28a37b5
Autor:
Kyosuke Takahashi, Kazuma Yamakawa, Anaar E. Siletz, Morihiro Katsura, John B. Holcomb, Charles E. Wade, Jessica C. Cardenas, Erin E. Fox, Morgan Schellenberg, Matthew Martin, Kenji Inaba, Kazuhide Matsushima
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 7, Pp 102568- (2024)
Background: Traumatic fibrinolytic dysfunction is often categorized into 3 phenotypes based on the result of thromboelastography (TEG) lysis at 30 minutes (LY30): fibrinolysis shutdown, physiologic fibrinolysis, and hyperfibrinolysis. However, the mo
Externí odkaz:
https://doaj.org/article/f4cf5330566f4d55b2eff6c34898cffe
Autor:
Alan D. Kaye, Joseph P. Tassin, William C. Upshaw, Camille M. Robichaux, Mark V. Frolov, Mark M. Dupaquier, Julia E. Fox, Jeffrey Sterritt, Jibin Mathew, Sahar Shekoohi, Adam M. Kaye, Amber N. Edinoff
Publikováno v:
Neurology and Therapy, Vol 13, Iss 4, Pp 965-973 (2024)
Abstract Etizolam is a thienodiazepine derivative which produces an anxiolytic effect similar to benzodiazepines such as alprazolam (Xanax). Like classic benzodiazepines, etizolam has a high affinity towards the GABAA receptor, and allosterically pot
Externí odkaz:
https://doaj.org/article/b991e6c6ce834132bf26f28725a9bf89
Autor:
Neha Sharma, Alex Chen, Leah Heinen, Ruth Liu, Dhruva J. Dwivedi, Ji Zhou, Manoj M. Lalu, Asher A. Mendelson, Braedon McDonald, Colin A. Kretz, Alison E. Fox-Robichaud, Patricia C. Liaw
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Introduction Despite older adults being more vulnerable to sepsis, most preclinical research on sepsis has been conducted using young animals. This results in decreased scientific validity since age is an independent predictor of poor outcom
Externí odkaz:
https://doaj.org/article/27fd2b1cf7f24f92a98ec9a101867c38
Autor:
Shannon M. Fernando, MD, Alexandre Tran, MD, Karim Soliman, MD, Barbara Flynn, BScRN, Thomas Oommen, PharmD, Li Wenzhe, MD, Neill K.J. Adhikari, MDCM, Salmaan Kanji, PharmD, Andrew J.E. Seely, MD, PhD, Alison E. Fox-Robichaud, MD, Randy S. Wax, MD, FCCM, Deborah J. Cook, MD, François Lamontagne, MD, Bram Rochwerg, MD, FCCM
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1110 (2024)
OBJECTIVES:. Although clinicians may use methylene blue (MB) in refractory septic shock, the effect of MB on patient-important outcomes remains uncertain. We conducted a systematic review and meta-analysis to investigate the benefits and harms of MB
Externí odkaz:
https://doaj.org/article/ae52b02a10dd4d4f8d7e87e5cd01a8f6
Autor:
J. Fairman, L. Roche, I. Pieslak, M. Lay, S. Corson, E. Fox, C. Luong, G. Koe, B. Lemos, R. Grove, L. Fradkin, J. Vernachio
Publikováno v:
BioTechniques, Vol 27, Iss 3, Pp 566-574 (1999)
An assay measuring RNA expression levels of a gene-encoded therapeutic must distinguish between endogenous mRNA and mRNA transcribed from the transgene. Specificity for the delivered transgene is especially critical when the treatment involves genes
Externí odkaz:
https://doaj.org/article/25eed53f6bdf441f87681c7698b2689a
Autor:
Roy H. Rhodes, Gordon L. Love, Fernanda Da Silva Lameira, Maryam Sadough Shahmirzadi, Sharon E. Fox, Richard S. Vander Heide
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-23 (2024)
Abstract Background Hypercytokinemia, the renin-angiotensin system, hypoxia, immune dysregulation, and vasculopathy with evidence of immune-related damage are implicated in brain morbidity in COVID-19 along with a wide variety of genomic and environm
Externí odkaz:
https://doaj.org/article/a1935f8cd2b342dba68ccc4fae210f34
Autor:
Caitlyn G. Peters, Noam Y. Harel, Joseph P. Weir, Yu-Kuang Wu, Lynda M. Murray, Jorge Chavez, Fiona E. Fox, Christopher P. Cardozo, Jill M. Wecht
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 838-847 (2023)
Transcutaneous spinal cord stimulation (tSCS) is an emerging therapeutic strategy to target spinal autonomic circuitry to normalize and stabilize blood pressure (BP) in hypotensive persons living with chronic spinal cord injury (SCI). Our aim is to d
Externí odkaz:
https://doaj.org/article/92d3d0229ff14f9cbed0b912eb679a12
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Modality transitions represent a period of significant change that can impact health related quality of life (HRQoL). We explored the HRQoL of adults transitioning to new or different dialysis modalities. Methods We recruited elig
Externí odkaz:
https://doaj.org/article/6e35ae9542584d0f8a33787ad36796a6
Autor:
Neha Sharma, Damian Chwastek, Dhruva J. Dwivedi, Jared Schlechte, Ian-Ling Yu, Braedon McDonald, Jaskirat Arora, Erblin Cani, Mikaela Eng, Doreen Engelberts, Eva Kuhar, Sarah K. Medeiros, Stephane L. Bourque, Gediminas Cepinskas, Sean E. Gill, Forough Jahandideh, Kimberly F. Macala, Sareh Panahi, Cynthia Pape, David Sontag, Janet Sunohara-Neilson, Dean A. Fergusson, Alison E. Fox-Robichaud, Patricia C. Liaw, Manoj M. Lalu, Asher A. Mendelson, for the National Preclinical Sepsis Platform, Sepsis Canada
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Background Preclinical sepsis models have been criticized for their inability to recapitulate human sepsis and suffer from methodological shortcomings that limit external validity and reproducibility. The National Preclinical Sepsis Platform
Externí odkaz:
https://doaj.org/article/2a7fa924fb5b4658b0da38387de75a6e