Výsledky vyhledávání - "E. F. Repina"

ASSESSMENT OF THE FUNCTIONAL STATE OF THE LIVER AND KIDNEYS OF LABORATORY ANIMALS AFTER EXPOSURE TO CADMIUM IN A SUB-EXPERIMENT

Autor: Munira M. Ziatdinova, N. Yu. Khusnutdinova, Ya.V. Valova, D. A. Smolyankin, Anna S. Fazlyeva, G. V. Timasheva, E. F. Repina, Samat S. Baygildin

Publikováno v: Trace Elements in Medicine (Moscow). 22:72-77

The paper presents the results of studies of metabolic changes in the blood serum of rats on the background of oral administration of cadmium chloride for 2 months. Elevated serum hepatic enzymes are the main indicator of damage to hepatocytes caused

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea3f91d5619070beb3691b28929edf2c
https://doi.org/10.19112/2413-6174-2021-22-1-72-77

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Metabolic changes on the background of acute exposure to paracetamol and evaluation of the effectiveness of hepatoprotective drug

Autor: G. F. Mukhammadieva, N. Yu. Khusnutdinova, D. A. Smolyankin, E. F. Repina, D. O. Karimov, Samat S. Baygildin, G. V. Timasheva

Publikováno v: Hygiene and sanitation. 99:1016-1021

Introduction In modern conditions, caused by the pandemic of a new type of viral infection Covid 19, the use of paracetamol, which has hepatotoxic properties in overdose, has increased It seems relevant to study metabolic disorders in the liver in ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32f8d642efc39ba8ade7995c787dc064
https://doi.org/10.47470/0016-9900-2020-99-9-1016-1021

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Morphological changes in parenchymal organs of laboratory animals in acute effect of carbon tetrachloride

Autor: Alfiya R. Gimadieva, Nadezhda Yu. Khusnutdinova, E. F. Repina, D. O. Karimov, L. A. Musina, D. A. Smolyankin, G. V. Timasheva, Samat S. Baygildin

Publikováno v: Hygiene and sanitation. 99:1001-1006

Introduction. Among noninfectious diseases, one of the leading places belongs to pathologies caused by the action of industrial toxicants. In this regard, the search for drugs for the prevention and treatment of various intoxications is one of the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa5a5301268fa4bb3236865a7fc71693
https://doi.org/10.47470/0016-9900-2020-99-9-1001-1006

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Metabolic and molecular-genetic changes in the liver during carbon tetrachloride intoxication

Autor: Samat S. Baygildin, Yana V. Valova, E. F. Repina, Tatyana G. Kutlina, D. O. Karimov, G. F. Mukhammadiyeva

Publikováno v: Hygiene and sanitation. 99:996-1000

Introduction. Toxic hepatitis (TH) is a complex and multifaceted disease, the development of which is mediated by a complex of biochemical and molecular genetic interactions. The current understanding of the pathogenesis of TH and, as a consequence,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40245ba610824c7e4c85ce67ca6ffd30
https://doi.org/10.47470/0016-9900-2020-99-9-996-1000

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PECULIARITIES OF METABOLIC CHANGES IN EXPERIMENTAL ANIMALS AT EARLY TERMS OF PHARMACOLOGICAL CORRECTION OF TOXIC LIVER DISEASES

Autor: E. F. Repina, G. V. Timasheva, N. Yu. Khusnutdinova, S. S. Baigildin, A. B. Bakirov, D. O. Karimov, D. A. Smolyankin, G. F. Mukhammadieva

Publikováno v: Toxicological Review. :13-19

The paper presents the results of studies on metabolic changes in experimental animals with acute tetrachloromethane poisoning and further damage correction using substances possessing hepatoprotective properties: oxymethyluracil, ademethionine and e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b7b91b1e9360a204aea1b8bf772b4ab
https://doi.org/10.36946/0869-7922-2020-1-13-19

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CHANGE OF THE PROFILE OF EXPRESSION OF ADAPTIVE RESPONSE GENES IN TOXIC HEPATITIS OF DIFFERENT ETIOLOGY

Autor: Denis O. Karimov, E. F. Repina, G. F. Mukhammadiyeva, N. Yu. Khusnutdinova, T. G. Kutlina, Yana V. Valova

Publikováno v: Hygiene and sanitation. 98:1021-1025

Introduction. In Russia, the problem of toxic hepatitis is of great importance and relevance. The etiology of toxic hepatitis (industrial toxicants, drugs, ethanol) and, as a consequence, pathogenesis may have significant differences at the molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99bdafb046ec8131b822458aefa23a21
https://doi.org/10.18821/0016-9900-2019-98-9-1021-1025

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ANALYSIS OF CHANGES IN CASP7 AND CHEK1 GENES EXPRESSION IN LIVER TOXIC DAMAGE INDUCED BY TETRACHLORMETHANE AGAINST THE BACKGROUND OF HEPATOPROTECTORS

Autor: N. Yu. Khusnutdinova, T. G. Kutlina, G. F. Mukhammadieva, E. F. Repina, Ya.V. Valova, D. O. Karimov

Publikováno v: Hygiene and sanitation. 98:1011-1014

Introduction. The effect of hepatoprotectors on the expression of genes involved in the regulation of apoptosis and the cell cycle (Casp7 and Chek1) under the toxic effects of carbon tetrachloride (carbon tetrachloride, CCl4) was studied. Material an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6118662cbde2380823ee1bdeae1c451f
https://doi.org/10.18821/0016-9900-2019-98-9-1011-1014

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EXPERIMENTAL EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF A NEW COMPOSITION OF OXIMETHURACIL WITH CARBONIC ACIDS

Autor: G. F. Mukhammadieva, A. R. Gimadieva, D. O. Karimov, G. V. Timasheva, L. A. Musina, E. F. Repina, N. Yu. Khusnutdinova, Samat S. Baygildin

Publikováno v: Hygiene and sanitation. 98:1004-1010

Introduction. The high frequency of chemical poisoning is accompanied by an increase in the absolute number of cases of chemical damage to the liver. There is growing evidence that acute chemical poisoning in Russia is among the leading non-infectiou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::296c2ea11d7df6abd5d45973266bd2fa
https://doi.org/10.18821/0016-9900-2019-98-9-1004-1010

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INFORMATIVE CHANGES IN INDICATORS OF HOMEOSTASIS TO THE ASSESSMENT OF INDIVIDUAL RISK ADAPTATION DISORDERS IN WORKERS OF THE CHEMICAL INDUSTRY

Autor: L M Masyagutova, E T Valeeva, G. V. Timasheva, E. F. Repina

Publikováno v: Russian Clinical Laboratory Diagnostics. 64:29-33

This paper reviews the results of complex laboratory examinations among workers manufacturing fiber glass. The most pronounced and early changes in oxidative metabolism processes (reduced catalase activity, increased malonic dialdehyde) and rates of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a2f25360c92f16c3fd8b738cbf6494
https://doi.org/10.18821/0869-2084-2019-64-1-29-33

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