Výsledky vyhledávání - "E. F. McKone"

Akademický článek

Targeting the PI3K/Akt/mTOR signalling pathway in Cystic Fibrosis

Autor: R. Reilly, M. S. Mroz, E. Dempsey, K. Wynne, S. J. Keely, E. F. McKone, C. Hiebel, C. Behl, J. A. Coppinger

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

Abstract Deletion of phenylalanine 508 of the cystic fibrosis transmembrane conductance regulator (ΔF508 CFTR) is a major cause of cystic fibrosis (CF), one of the most common inherited childhood diseases. ΔF508 CFTR is a trafficking mutant that is

Externí odkaz: https://doaj.org/article/83f7d91151ee4471ab8b716bf6da8bf0

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Experience using centralized spirometry in the phase 2 randomized, placebo-controlled, double-blind trial of denufosol in patients with mild to moderate cystic fibrosis

Autor: C H, Goss, E F, McKone, D, Mathews, D, Kerr, J S, Wanger, S P, Millard, Christopher, Harris

Publikováno v: Journal of Cystic Fibrosis. (2):147-153

Background Centralized spirometry may significantly improve quality of spirometry and reduce variability of this outcome measure in clinical trials in cystic fibrosis (CF). Methods Spirometry was performed during the phase 2 randomized, placebo-contr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610a08f1d84b08cdc7f346fcca646827

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