Zobrazeno 1 - 10
of 31
pro vyhledávání: '"E. F. Kolesanova"'
Effect of Lipid Components on Immunogenicity of Synthetic Fragment of Hepatitis C Virus NS4A Antigen
Autor:
A. N. Belyavtsev, N. S. Shastina, V. V. Kupriyanov, L. I. Nikolaeva, M. V. Melnikova, E. F. Kolesanova, M. Yu. Shimchishina, I. V. Kapustin
Publikováno v:
Russian Journal of Bioorganic Chemistry. 48:621-627
Autor:
A. N. Belyavtsev, R. G. Vahrenev, E. F. Kolesanova, M. V. Melnikova, L. I. Nikolaeva, G. V. Sapronov, N. S. Shastina, N. G. Shevchenko
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:713-718
Abstract— The work is aimed at the synthesis and analysis from NS4A of hepatitis C virus (HCV) antigen peptide fragment that contains a conserved B-cell and T-helper epitopes. The 24-mer peptide VIVGRIILSGRPAVIPDREVLYRK-NH2, which contains the main
Autor:
E I Korotkevich, L V Kostryukova, E. F. Kolesanova, T. I. Torkhovskaya, M.A. Sanzhakov, N A Orlova, E G Tikhonova, Yu.A. Tereshkina, Yu.Yu. Khudoklinova
Publikováno v:
Journal of drug targeting. 30(3)
The review highlights the safety issues of drug delivery systems based on liposomes. Due to their small sizes (about 80-120 nm, sometimes even smaller), phospholipid nanoparticles interact intensively with living systems during parenteral administrat
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 9:217-227
Publikováno v:
Biomeditsinskaya Khimiya. 61:254-264
In order to surpass the problem of genetic variability of hepatitis C virus envelope proteins during vaccine development, we used the so-called "reverse vaccinology"approach--"from genome to vaccine". Database of HCV protein sequences was designed, v
Autor:
A. I. Khoruzhenko, E. A. Egorova, V. F. Shalak, L. V. Skoroda, A. A. Mishin, M. I. Kovalenko, Boris Negrutskii, A. A. Vislovukh, Oleksandra V. Novosylna, M. S. Krotevych, E. F. Kolesanova
Publikováno v:
Biopolymers and Cell, Vol 30, Iss 6, Pp 454-461 (2014)
Aim. We intend to characterize the new peptide-specific antibodies against the isoform 2 of translation elongation factor 1A (eEF1A2) and determine its presence in the postoperative samples of human breast, lung and stomach tumor tissues. Methods. Th
Autor:
A. A. Moisa, E. F. Kolesanova
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 4:321-332
Publikováno v:
Scopus-Elsevier
Virus entry into a host cell comprises the first step of the viral life cycle. Blockage of this process can stop or prevent the rise of the infection. Development of compounds exhibiting directed blocking activity requires information about host cell
Autor:
E. Yu. Aleshina, E. F. Kolesanova, Oleg N. Kharybin, M. A. Sanzhakov, A. A. Moisa, N. V. Pyndyk, Eugene N. Nikolaev
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 2:288-292
The peptide RHDSGY, a fragment of the human β-amyloid Zn-binding site, and its isomers RH(D-Asp)SGY and RH(β-Asp)SGY have been obtained as amides by means of solid-phase synthesis and analyzed by HPLC and various mass spectrometric methods. The pro
Autor:
Alexander I. Archakov, B. N. Sobolev, E. F. Kolesanova, Vladimir Poroikov, Ludmila V. Olenina
Publikováno v:
Current Computer Aided-Drug Design. 1:207-222
Development of computer methods in molecular biology and fast growth of microbial genomics data enabled new approach based on selecting in silico antigenic components to design vaccine constructs. It is expected that application of this technology wi