The epidemiology of sepsis in Brazilian intensive care units (the Sepsis PREvalence Assessment Database, SPREAD): an observational study

Autor: Zajac, S R, Bley, M V, Scazufca, A, Rosateli, P, Reis, T, Junior, A Nogueira, Neto, P A Nunes, Filho, I L S, Lima, H, Vieira, M, Zanchet, M, Ferreira, I, Miguita, R, Petisco, G M, Westphal, G A, Santos, J R P, Damasceno, V, dos Santos, J T, Fernandes, F, Almeida, EP, Lemos, M, Lima, M F A, Camacho, R, Ribeiro, A, Douglas, M O G, Mattei, G A, Junior, E A, Ferreira, P, Rabelo, H R M P, Pinto, S P S, Fontes, L E, Machado, D, Guitzel, M, Lucio, M, Conceição, C N P, Barros, A, Salgado, D, Veiga, V C, Rojas, S S O, de Paula, KM, Hatum, R, Fraenkel, L, Viana, W N, Santos, A P G, Rabello, L, Tanaka, L, Uchoa, M, Moura, M D, Gneco, H, Buarque, M F, Monteiro, K, Nassar, A P, Jr, Koterba, E, Teixeira, M J, Falcão, A L E, Pinto, V G S, Junior, J M M, Gut, A L, Stefano, L M, Damasceno, M, Lontra, M V, Cozzani, C, Sobrinho, E B, Lage, S G, Kopel, L, Youssef, N C M, Sanches, L C, Amendola, C P, Kmohan, C, Silva, C B, Schifelbain, L, Bellotto, E, Viecili, P, Azevedo, L, Monteiro, L, Vieira, S, Abrão, A M, Moraes, A P, Insaurrale, H, Gadelha, M, Marisa, D, Diniz, R N, Romano, E R, Luzzi, S, Rezende, E, Filho, M C, Martins, R H F C, Carvalho, F B, Moreira, G C, Paula, J, Haag, F, Jr, Lucena, FS, Machado, R S, Filho, W O, Cavalcante, L O, Filho, H Carvalho, Lima, G S, Trombka, J N, Machado, E C, Bainy, M P, Ramos, C H, Hoppe, C, Luckmeyer, G D, Vogas, C, Thompson, M M, Sousa, R K, Fernandes, R, Lourenço, E, Peixoto, G L, Mocelin, A, Silva, M M L, Neto, J S A, Villela, C, Mendonça, S L, Prado, S C, Goulart, R, Duarte, J J L, Junior, H A O, Andrade, J N, Souza, L F, Fernandes, L, Neto, M L, Fernandes, S S, Amâncio, F, Versiani, J C, Pitanga, F, Alcantara, M B, Reiff, C C, Rosenblat, R, Nobrega, M S, Nobrega, M L F S, Costa, G, Assunção, N, Almeida, E P, Neder, L, Almeida, R, Fuck, J, Souza, R M, Ribeiro, A G, Alves, A A G, Carvalho, S H C, Arbex, M, Oliveira, E C, Melo, R S, Conde, K, Abreu, N Q, Melo, C L T, Carvalho, A A, Lannes, R, Missaka, H, Furtado, A H, Jr, Peixoto, A A, Jr, Maia, I, Pincelli, M P, Yunes, M P, Pessoa, A N, Figueiredo, S, Botoni, F A, Cunha, C T, Olson, F A, Franco, R, Bemfica, A F, Junior, A D F, Ferreira, E L A, Messeder, O, Passos, R, Lira, J A, Vilela, C A, Junior, S M D, Ferreira, C S, Muller, O P J A, dos Santos, R Perreira, Rubini, P, Monteiro, D, Rodrigues, L E, Ruivo, G F, Gomes, M C, Egito, E, Assef, M G, Lima, M A M, Borges, A F, Jezler, S, Mendes, C, Gottardo, P C, Lima, R, Filho, C M F, Campagnucci, V P, Solino, I, Lorca, A P, Rodrigues, G M, Gerent, K B, Barbosa, O, Filho, G T Henriques, Troncoso, E, Ventura, A, Silva, M A, Houly, J G, Pimentel, J P M, Ramos, R A, Gianini, F, Casemiro, B, Pinto, E M, Silva, G A, Sebold, M, Vieira, E, Ferreira, R, Gomes, L A, Lovato, W J, Dantas, W, Ishy, L, Moreira, J, Gagliardi, I, Goes, L O, Vendrame, L S, Guimarães, H P, Gois, A, Machado, F R, Rodrigues, M, Jr, Vieira, P C B, Bittencourt, W, Melnick, E, Schneider, M, Rezegue, L, Nogueira, N J M, Godinho, E P, Mazza, B F, Paciencia, L E, Ferraz, S, Imamura, C R A, Tavares, J, Santos, J C, Vale, E, Filho, J Mugait, Tannous, L A, João, P G D, Geral, C T I, Matera, A P, Matsui, M, Neto, E Eberhart, Pinheiro, B V, Carvalho, E V, Matos, H, Lippi, M, Campos, A L, Albuquerque, D C, Castiglioni, D, Silva, G S, Cunha, S, Novello, E, Silva, M E B, Grion, C, Festti, J, Souza, C R A, Mecatti, G C, Junqueira, E B, Dutra, R S, Mirachi, G B, Mendes, D A, Moura, E M F, Silva, I F, Mota, M G P, Carneiro, T, Celso, A, Réa-Neto, A, Oliveira, M C, Japiassú, A, Castro, P P, Costa, H J M, Rolim, A V, Rocha, D, Righy, C, Santos, V, Fernandino, B, Pereira, A L, Rego, V L D, Melo, L A, Guilherme, L, Ferro, H Chagas, Silva, F J L, Carrasco, H V C J, El-Fakouri, S, Alvarez, J, de Castro, D, Shiavetto, P M, Gallate, S R, Filho, E Thomé, Veneziano, S G, Antoniazzi, P, Filho, W H, Sadala, P, Balbino, C, Moreno, G, Dias, M S F, Lopez, R P, Rodrigues, M L, Terceiro, J, Serpa, M F, Santos, L, Lippi, M M, Machado, Flavia R, Cavalcanti, Alexandre Biasi, Bozza, Fernando Augusto, Ferreira, Elaine M, Angotti Carrara, Fernanda Sousa, Sousa, Juliana Lubarino, Caixeta, Noemi, Salomao, Reinaldo, Angus, Derek C, Pontes Azevedo, Luciano Cesar

Publikováno v: In The Lancet Infectious Diseases November 2017 17(11):1180-1189

Data from Medulloblastomas Derived from Cxcr6 Mutant Mice Respond to Treatment with a Smoothened Inhibitor

Autor: Tom Curran, Dennis S. Rice, Derek E. Eberhart, Hiromichi Kimura, Justyna T. Romer, Ken Sasai

The sonic hedgehog (Shh) pathway is activated in ∼30% of human medulloblastoma resulting in increased expression of downstream target genes. In about half of these cases, this has been shown to be a consequence of mutations in regulatory genes with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7a4acba7a00c9add39c8d85fe408907
https://doi.org/10.1158/0008-5472.c.6496787

Contributors

Autor: Ricardo Almada-Monter, Omar A. Álvarez-Gonzaga, James S.M. Anderson, Paul W. Ayers, José E. Barquera-Lozada, Yoshio Barrera, Giovanna Bruno, Pablo Carpio-Martínez, Julia Contreras-García, Fernando Cortés-Guzmán, Aurora Costales, Emiliano Dorantes-Hernández, Mark E. Eberhart, Alberto Fernández-Alarcón, Evelio Francisco, Marco Antonio Garcia-Revilla, Carlo Gatti, Rosa M. Gómez-Espinosa, José M. Guevara-Vela, Jesús Hernández-Trujillo, Jesús Jara-Cortés, Samantha Jenkins, Laurent Joubert, Airi Kawasaki, Steven R. Kirk, Bruno Landeros-Rivera, Chérif F. Matta, Héctor D. Morales-Rodríguez, Amanda Morgenstern, Aldo de Jesús Mortera-Carbonell, Xing Nie, Eduardo Orozco-Valdespino, Ángel Martín Pendás, David I. Ramírez-Palma, Tomás Rocha-Rinza, Juan I. Rodríguez, Shant Shahbazian, David C. Thompson, Vincent Tognetti, Ismael Vargas-Rodríguez, Timothy R. Wilson, Tianlv Xu, Yong Yang

Publikováno v: Advances in Quantum Chemical Topology Beyond QTAIM ISBN: 9780323908917

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a6a5fbceb6d5d85ceacaebaa187cc9c
https://doi.org/10.1016/b978-0-323-90891-7.09992-8

Geometry of Charge Density as a Reporter on the Role of the Protein Scaffold in Enzymatic Catalysis: Electrostatic Preorganization and Beyond

Autor: Mark E. Eberhart, Timothy R. Wilson, Nathaniel W. Johnston, Anastassia N. Alexandrova

Publikováno v: Journal of chemical theory and computation, vol 19, iss 3

Enzymes host active sites inside protein macromolecules, which have diverse, often incredibly complex, and atom-expensive structures. It is an outstanding question what the role of these expensive scaffolds might be in enzymatic catalysis. Answering

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96476665ca67724bd8588e155333b55f
https://pubmed.ncbi.nlm.nih.gov/36562645

Electron Density Geometry and the Quantum Theory of Atoms in Molecules

Autor: Timothy R. Wilson, Anastassia N. Alexandrova, M. E. Eberhart

Publikováno v: The journal of physical chemistry. A, vol 125, iss 50

A novel form of charge density analysis, that of isosurface curvature redistribution, is formulated and applied to the toy problem of carbonyl oxygen activation in formaldehyde. The isosurface representation of the electron charge density allows us t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288f66bed4a241fa4880994abbfb39dc
https://doi.org/10.33774/chemrxiv-2021-9tjtw-v2