Zobrazeno 1 - 10
of 17
pro vyhledávání: '"E. E. Opas"'
Autor:
A. Markatos, E E Opas, D. Frankenfield, M. Shea, J.G. Seedor, H Klein, R. Balena, S C Lee, Elizabeth R. Myers, Brian C. Toolan
Publikováno v:
Journal of Clinical Investigation. 92:2577-2586
This study examined the effect of 2 yr of treatment with the aminobisphosphonate alendronate (ALN) (0.05 or 0.25 mg/kg i.v. ALN every 2 wk) on estrogen deficiency bone loss and bone strength changes in ovariectomized (OVX) baboons (n = 7 per group) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa994fabd16020dbec84d6ff3fc8cec3
https://doi.org/10.1172/jci116872
https://doi.org/10.1172/jci116872
Autor:
Alan L. Maycock, David Fletcher, S. Shah, William A. Hanlon, Richard A. Mumford, M. A. Navia, John L. Humes, J. B. Doherty, Stephen G. Pacholok, E. E. Opas, Morris Zimmerman, Bonnie M. Ashe, Paul E. Finke, C. P. Dorn, Bonney Rj, Philip Davies
Publikováno v:
Annals of the New York Academy of Sciences. 624:219-229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829963df75e64ac67de1a84861da207d
https://doi.org/10.1111/j.1749-6632.1991.tb17021.x
https://doi.org/10.1111/j.1749-6632.1991.tb17021.x
Autor:
Robert N. Young, J. G. Seedor, Gideon A. Rodan, E. E. Opas, Peter C. Tyler, Rejean Ruel, Yongxin Han, Laurent Frédéric Gil
Publikováno v:
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Conjugates of bisphosphonates (potential bone resorption inhibitors) and prostaglandin E2 (a bone formation enhancer) were prepared and evaluated for their ability to bind to bone and to liberate, enzymatically, free PGE2. The conjugate 3, an amide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405551957cdba7c7bd56c30ef47e87a0
https://pubmed.ncbi.nlm.nih.gov/10400344
https://pubmed.ncbi.nlm.nih.gov/10400344
Autor:
Rejean Fortin, C. Chan, H. Piechuta, S. S. Pong, D. Denis, DeHaven Rn, Joshua Rokach, Howard E. Morton, Hollis R. Williams, Larry Peterson, Stella Charleson, C. Rouzer, L. Charette, E. Champion, Thomas R. Jones, Robert Zamboni, Joe Metzger, Denis Riendeau, S. L. Hopple, C. S. Mcfarlane, G. Eiermann, Jillian F. Evans, Roger Meurer, Robert N. Young, T. Bach, Richard Frenette, A. Foster, L. Hupe, John L. Humes, Silvi Luell, Douglas K. Miller, E. E. Opas, Serge Leger, C. Leveillé, Y. Guidon, Jacques-Yves Gauthier, Richard A. F. Dixon, Anthony W. Ford-Hutchinson, P. Masson, A. Lord, Yves Girard, Diane Ethier, M. Belley, John W. Gillard, Pierre Hamel, D. E. Mc McIntyre, Christiane Yoakim, M. Barth, Stephen G. Pacholok
Publikováno v:
Asthma Treatment ISBN: 9781461365259
The peptide leukotrienes LTC4, D4 and E4 collectively account for the biological activity known as slow-reacting substance of anaphylaxis (SRS-A). These metabolites of arachidonic acid are thought to play a role in lung pathophysiology. A role in ast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0845cec71fa4977069e37196521ef540
https://doi.org/10.1007/978-1-4615-3446-4_8
https://doi.org/10.1007/978-1-4615-3446-4_8
Publikováno v:
Annals of the New York Academy of Sciences. 624
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d676b583cc7662e56dea6331df6c5f2b
https://pubmed.ncbi.nlm.nih.gov/2064243
https://pubmed.ncbi.nlm.nih.gov/2064243
Publikováno v:
British Journal of Dermatology. 120:49-58
Homogenates of normal human epidermis synthesized 12-hydroxyeicosatetraenoic acid (12-HETE) when incubated in vitro with arachidonic acid. The stereoconfigurations of the C-12 hydroxyl isomers were determined by incubation with potato 5-lipoxygenase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53800973ca7e65fad6f93dbd0488149
https://doi.org/10.1111/j.1365-2133.1989.tb07765.x
https://doi.org/10.1111/j.1365-2133.1989.tb07765.x
Autor:
Paul H. Gale, Roger Meurer, Norman P. Jensen, R. J. Bonney, John L. Humes, Robert W. Egan, Stephen G. Pacholok, E. E. Opas, Harry W. Dougherty, John A Macdonald, P. Davies, Milton L. Hammond, Michael Chang, Kathryn L. Thompson, Robert A. Zambias
Publikováno v:
Biochemical Pharmacology. 36:3885-3891
The biochemical and biological profile of a topical anti-inflammatory agent, 2,3-dihydro-6-[3-(2-hydroxymethyl)phenyl-2-propenyl]-5-benzofuranol (L-651,896), is described. L-651,896 inhibited the 5-lipoxygenase of rat basophilic leukemia cells with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5911318622f282421344e7e1d23cb3ba
https://doi.org/10.1016/0006-2952(87)90454-0
https://doi.org/10.1016/0006-2952(87)90454-0
Publikováno v:
Journal of Biological Chemistry. 256:12523-12528
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be95ccc52f7cf390ef80f6878e053fa3
https://doi.org/10.1016/s0021-9258(18)43306-6
https://doi.org/10.1016/s0021-9258(18)43306-6
Publikováno v:
Journal of Investigative Dermatology. (4):253-256
Topical application of arachidonic acid on mouse ears induces the synthesis of prostaglandin E2 and leukotrienes C4 and D4. The increased tissue levels of these products are quantitated by radioimmunoassay. The identity of the leukotrienes was confir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c082933c34f70040549ba2e9993e568
Publikováno v:
Federation proceedings. 44(14)
Resident mouse peritoneal macrophages when exposed to zymosan during the first day of cell culture synthesize and secrete large amounts of prostaglandin E2 and leukotriene (LT) C4, the respective products of cyclooxygenase- and 5-lipoxygenase-catalyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::546681545fd00216520fc3b0c65c118c
https://pubmed.ncbi.nlm.nih.gov/2996948
https://pubmed.ncbi.nlm.nih.gov/2996948