Zobrazeno 1 - 10
of 153
pro vyhledávání: '"E. E. Moran"'
Autor:
S. Biggs-Cicatelli, Robert Burden, James E. Moon, James F. Cummings, E. E. Moran, Wendell D. Zollinger, Paul B. Keiser, Deborah H. Schmiel, Lori Miller, Valerian B. Pinto, Robert A. Bowden
Publikováno v:
Vaccine. 29:1413-1420
This phase I clinical trial assessed the safety and immunogenicity of a native outer membrane vesicle (NOMV) vaccine prepared from an lpxL1(-) synX(-) mutant of strain 8570(B:4:P1.19,15:L8-5) of Neisseria meningitidis. Additional mutations enhance th
Autor:
Valerian B. Pinto, Paul B. Keiser, Mark B. Stoddard, Ping Chen, Wendell D. Zollinger, Joseph E. Labrie, Deborah H. Schmiel, E. E. Moran, Trinka S. Coster, Barnett Gibbs
Publikováno v:
Vaccine. 28:6970-6976
This phase 1 clinical trial assessed the safety and immunogenicity of a native outer membrane vesicle (NOMV) vaccine prepared from a lpxL2(-) synX(-) mutant of strain 44/76 with opcA expression stabilized. Thirty-four volunteers were assigned to one
Autor:
Victor Agnello, Stephen Marks, Brenda L. Brandt, Wendell D. Zollinger, E. E. Moran, Rohit K. Katial
Publikováno v:
Infection and Immunity. 70:702-707
The presently licensed meningococcal vaccine is a tetravalent capsular polysaccharide vaccine that induces immunity to serogroups A, C, Y, and W-135 but not to group B, which causes nearly half of the meningitis cases in the United States. The purpos
Autor:
Wendell D. Zollinger, Nancy B. Saunders, E. E. Moran, David R. Shoemaker, Thomas Larsen, Brenda L. Brandt
Publikováno v:
Infection and Immunity. 67:113-119
Colonization of the human nasopharyngeal region by Neisseria meningitidis is believed to lead to natural immunity. Although the presence of bactericidal antibody in serum has been correlated with immunity to meningococcal disease, mucosal immunity at
Autor:
Janet S. Foster, Wendell D. Zollinger, Douglas B. Tang, E. E. Moran, Andrew F. Trofa, Joseph J. Drabick
Publikováno v:
Vaccine. 15:1144-1148
Cimetidine (CIM) is an H2-receptor antagonist with a long history of clinical use in peptic ulcer disease. In addition to its inhibitory effect upon gastric acid secretion, CIM can also block histamine-mediated immunosuppression by inhibiting H2 rece
Publikováno v:
Infection and Immunity. 65:1053-1060
Reports on the bactericidal activities of antibodies to group B Neisseria meningitidis capsular polysaccharide (B PS) are conflicting. Using three different complement sources, we analyzed the bactericidal activities of sera of juvenile rhesus monkey
Publikováno v:
Infection and Immunity. 62:5290-5295
The influence of lipopolysaccharide (LPS) expression on the sensitivity of Neisseria meningitidis to serum bactericidal activity was investigated by using a series of variants that expressed different LPS determinants. For each of two different strai
Autor:
Wendell D. Zollinger, E. E. Moran
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 85
Over 20 years after the development of the meningococcal A and C vaccines, an effective vaccine against Neisseria meningitidis group B is still lacking. Major obstacles in the development of a B vaccine have been the remarkable capacity of the organi
Autor:
Brenda L. Brandt, L. O. FrØholm, J. S. Ray, E. E. Moran, Wendell D. Zollinger, John W. Boslego
Publikováno v:
Antonie van Leeuwenhoek. 53:403-411
Several different meningococcal outer membrane protein vaccines have been prepared and used in human safety and immunogenicity studies. The results of these studies have led to some general conclusions regarding the human antibody response to these v
Publikováno v:
Antonie van Leeuwenhoek. 52:225-228