Zobrazeno 1 - 10
of 22
pro vyhledávání: '"E. E. Antoshina"'
Autor:
A. M. Scherbakov, T. I. Fetisov, D. V. Sorokin, V. Yu. Zinovieva, N. I. Moiseeva, L. A. Laletina, E. M. Kirilin, A. E. Manikaylo, L. Ya. Fomina, L. V. Mekheda, B. Yu. Bokhyan, E. A. Lesovaya, L. S. Trukhanova, T. G. Gor’kova, E. E. Antoshina, O. V. Morozova, K. I. Kirsanov, M. G. Yakubovskaya
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 2, Pp 58-65 (2022)
Introduction. The identification of predictive factors is a cornerstone task of modern oncology. The development of new targeted drugs determines the need for prediction of chemosensitivity of each patient to the prescribed therapy, in this regard, t
Externí odkaz:
https://doaj.org/article/71afdbbddba344529bf70f023fe79b06
Autor:
T. I. Fetisov, L. R. Tilova, E. A. Lesovaya, E. E. Antoshina, T. G. Gor’kova, L. S. Trukhanova, O. V. Morozova, E. V. Shipaeva, R. V. Ivanov, A. A. Purmal, G. A. Belitskiy, M. G. Yakubovskaya, A. V. Gudkov, K. V. Gurova, K. I. Kirsanov
Publikováno v:
Успехи молекулярной онкологии, Vol 3, Iss 3, Pp 67-72 (2016)
Curaxins represent low molecular weight carbazole derivatives, which simultaneously activate p53-dependent apoptosis and inhibit NF-kBdependent signal transduction pathways. Antitumor activity of curaxin CBL0137 was demonstrated in vivo on the model
Externí odkaz:
https://doaj.org/article/e6c530241b8c4a55a5f7c6a083abc4f0
Autor:
E E Antoshina, Anastasiya Kalinina, L S Trukhanova, Dmitriy B. Kazansky, L. M. Khromykh, Tatyana Gorkova, Mariya Zamkova
Publikováno v:
Journal of Immunotoxicology, Vol 16, Iss 1, Pp 182-190 (2019)
Cyclophilin A (CypA), an 18 kDa multi-functional protein with cis–trans isomerase activity, is both a ligand for cyclosporine A and a proinflammatory factor. CypA is also a chemoattractant for hemopoietic stem cells and progenitors of different lin
Autor:
Marianna G. Yakubovskaya, Daria Fleyshman, O. S. Morozova, Roman Ivanov, Elena V. Shipaeva, T. I. Fetisov, Andrei Purmal, Andrey Leonov, Andrei V. Gudkov, E E Antoshina, Ramiz M. Salimov, Varvara Maksimova, Ekaterina A. Lesovaya, Alfiya Safina, Gennady A. Belitsky, Katerina Gurova, L S Trukhanova, T G Gor'kova, Kirill I. Kirsanov
Publikováno v:
Cancer prevention research (Philadelphia, Pa.). 13(1)
Chemoprevention is considered a valid approach to reduce the incidence of colorectal cancer, one of the most common malignancies worldwide. Here, we investigated the tumor-preventive activity of curaxin CBL0137. This compound represents a new class o
Autor:
Natalia Khromova, Irina Golubeva, L S Trukhanova, L. M. Khromykh, Tatyana Gorkova, A A Kalinina, E E Antoshina, Igor Kudryavtsev, D. B. Kazansky
Publikováno v:
International Immunopharmacology. 94:107470
Cyclophilin A (CypA) is a pro-inflammatory factor with multiple immunomodulating effects. Here, we investigated the effects of recombinant human CypA (rhCypA) as a factor of antitumor host defense. Our results demonstrated that rhCypA dramatically in
Autor:
L S Trukhanova, Gennady A. Belitsky, Andrey V. Shubin, Kirill I. Kirsanov, Marianna G. Yakubovskaya, T G Gor'kova, E E Antoshina, Ekaterina A. Lesovaya, Ilya V. Demidyuk
Publikováno v:
Bulletin of experimental biology and medicine. 164(5)
Studies of the molecular mechanisms of esophageal cancer development have to be carried out on sufficient amount of tumor material, obtained under conditions of controlled exposure to carcinogenic factors. Esophageal cancer models on laboratory anima
Autor:
E E Antoshina, Gennady A. Belitsky, Mikhail V. Blagosklonny, L S Trukhanova, Elena V. Shipaeva, Ramiz M. Salimov, Marianna G. Yakubovskaya, Olga B. Chernova, T G Gor'kova, Ekaterina A. Lesovaya, Kirill I. Kirsanov
Publikováno v:
Oncotarget
Benign prostatic hyperplasia (BPH) is the most common age-related disease in men. Here we tested the efficacy of Rapatar, a micellar nanoformulation of rapamycin, in two rat models of BPH: testosterone-induced and sulpiride-induced hyperplasia in ven
Autor:
T. S. Kolesnichenko, E. E. Antoshina
Publikováno v:
Bulletin of Experimental Biology and Medicine. 125:597-600
The incidence of epithelial hyperplasia is studied in cultures of aggregates from epithelial and mesenchymal cells of embryonal lungs of intact and urethrane-treated Asn and C57B1 mice (transplacental urethrane, 3 g/kg). In the control, epithelial hy
Autor:
V A, Kobliakov, E E, Antoshina, T G, Gor'kova, I L, Gol'dman, L S, Trukhanova, E R, Sadchikova
Publikováno v:
Voprosy onkologii. 58(5)
There was studied effect of recombinant form of human breast milk component-lactoferrin, received from milk of goats-producers (neolactoferrin), on growth of transplantable tumor of the cervix in mice (TTC-5). Neolactoferrin in dose of 100 mg/kg and
Publikováno v:
Voprosy onkologii. 52(1)
It was investigated whether preliminary administration of water with reduced Deuterium content may modify the inhibitory effect of the water given to BDF1 and CDA mice on the day of tumor transplantation. Two models were used: Lewis lung carcinoma (L