Zobrazeno 1 - 10
of 83
pro vyhledávání: '"E. Duzic"'
Publikováno v:
Journal of Biological Chemistry. 267:9844-9851
alpha 2-Adrenergic receptor (alpha 2-AR) subtypes couple to pertussis toxin (PT)-sensitive G-proteins to elicit both stimulatory and inhibitory cell responses. Signal specificity may be generated by the ability of the receptor subtypes to "recognize"
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bb5d30a6c227154211c7c12e96dfd69
https://doi.org/10.1016/s0021-9258(19)50171-5
https://doi.org/10.1016/s0021-9258(19)50171-5
Publikováno v:
Journal of Biological Chemistry. 267:9852-9857
Cell to cell communication by many hormones and neurotransmitters involves three major entities: receptor (R), G-protein (G), and effector molecule (E). Plasticity in this system is conferred by the existence of each entity as isoforms or closely rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::464bafdf11f4449fc96701d526918268
https://doi.org/10.1016/s0021-9258(19)50172-7
https://doi.org/10.1016/s0021-9258(19)50172-7
Publikováno v:
Journal of Biological Chemistry. 266:10470-10478
alpha 2-Adrenergic receptors (alpha 2-AR) exist as subtypes that are expressed in a tissue-specific manner and differ in 1) their ligand recognition properties, 2) their extent of receptor protein glycosylation, and possible 3) their mechanism of sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a60338e8f8db1ff84f130644cb0cdb1b
https://doi.org/10.1016/s0021-9258(18)99248-3
https://doi.org/10.1016/s0021-9258(18)99248-3
Publikováno v:
Molecular genetics and genomics : MGG. 265(6)
We show that co-expression of rat Galphas together with type I, II, IV, or VI mammalian adenylyl cyclase (AC) can suppress the growth defect of cyr1 strains of Saccharomyces cerevisiae, which lack a functional endogenous AC. Complemention of cvr1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411f90363cb68c362e9e7e4395ee4f4b
https://pubmed.ncbi.nlm.nih.gov/11523785
https://pubmed.ncbi.nlm.nih.gov/11523785
Publikováno v:
The Journal of biological chemistry. 275(31)
Utilizing a functional screen in the yeast Saccharomyces cerevisiae we identified mammalian proteins that activate heterotrimeric G-protein signaling pathways in a receptor-independent fashion. One of the identified activators, termed AGS1 (for activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96eda9e471e38ed279fee0bf20250d68
https://pubmed.ncbi.nlm.nih.gov/10840027
https://pubmed.ncbi.nlm.nih.gov/10840027
Publikováno v:
The American journal of physiology. 273(2 Pt 2)
The influence of arginine vasopressin (AVP) on agonist-stimulated adenosine 3',5'-cyclic monophosphate (cAMP) accumulation was investigated in vascular smooth muscle cells (VSMC) cultured from rat thoracic aorta. Incubation of VSMC with AVP for 60 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87f97b9a662147d11f4a8990adbd0ef
https://pubmed.ncbi.nlm.nih.gov/9277517
https://pubmed.ncbi.nlm.nih.gov/9277517
Publikováno v:
Pharmacology. 52(4)
The receptor-coupling efficiency for epinephrine (EPI) stimulated heterotrimeric G protein activation was studied at the G protein level in membranes prepared from PC12 cells expressing cloned alpha 2D-adrenergic receptors (alpha 2D-AR). After pretre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29840c12616e411080bf392e22c58a73
https://pubmed.ncbi.nlm.nih.gov/8841088
https://pubmed.ncbi.nlm.nih.gov/8841088
Publikováno v:
Molecular pharmacology. 45(3)
The ability of agonist-occupied alpha 2D-adrenergic receptors to activate G proteins was measured in membranes from PC-12 cells stably expressing the cloned receptor, using guanosine-5'-O-(3-[35S]thio)triphosphate ([35S]GTP gamma S) binding as an end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a40388429d1f8f0bdea85e8c146a861
https://pubmed.ncbi.nlm.nih.gov/8145737
https://pubmed.ncbi.nlm.nih.gov/8145737
Publikováno v:
The American journal of physiology. 265(6 Pt 1)
Thromboxane A2 (TxA2), a platelet aggregator and vasoconstrictor, has been implicated as a potential mediator of cardiovascular diseases. Abuse of androgenic steroids has been associated with thrombotic cardiovascular diseases. Human erythroleukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd246be0d76872982428bcbf79c35b44
https://pubmed.ncbi.nlm.nih.gov/8279549
https://pubmed.ncbi.nlm.nih.gov/8279549
Autor:
E, Duzic, S M, Lanier
Publikováno v:
The Journal of biological chemistry. 267(33)
A number of diverse signaling pathways can be activated by G-protein coupled receptors. However, the factors involved in selection of a particular transduction pathway by a single receptor are not well understood. We are attempting to address this is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c5cbb672653d1e4f23cf5a4c3405021
https://pubmed.ncbi.nlm.nih.gov/1358886
https://pubmed.ncbi.nlm.nih.gov/1358886