Zobrazeno 1 - 10
of 82
pro vyhledávání: '"E. Douglas Wigle"'
Autor:
Anna Woo, Ashley Guttman, E. Douglas Wigle, William G. Williams, Joan Ivanov, Anthony Ralph-Edwards, Warren Ball, Meredith Linghorne, Harry Rakowski, Leonard Schwartz
Publikováno v:
Journal of the American College of Cardiology. 58:2313-2321
Objectives The aim of this study was to compare the survival of patients with hypertrophic cardiomyopathy (HCM) and resting left ventricular outflow tract (LVOT) obstruction managed with an invasive versus a conservative strategy. Background In patie
Autor:
Harry Rakowski, Christiane Gruner, Katherine A. Siminovitch, Melanie Care, E. Douglas Wigle, Gil Moravsky, Anna Woo
Publikováno v:
Circulation: Cardiovascular Genetics. 4:288-295
Background— Apical hypertrophic cardiomyopathy (HCM) is a unique form of HCM with left ventricular hypertrophy confined to the cardiac apex. The purpose of our study was to report genetic findings in a large series of unrelated patients with apical
Autor:
Hua Yang, Anna Woo, Harry Rakowski, E. Douglas Wigle, Shemy Carasso, Michal Jamorski, Anna S. Nikonova
Publikováno v:
Journal of the American Society of Echocardiography. 23:1081-1089
Hypertrophic cardiomyopathy (HCM) is associated with considerable phenotypic heterogeneity. Previous studies have shown a relationship between the degree and location of hypertrophy and the prognosis of patients. The aim of this study was to compare
Publikováno v:
Journal of the American Society of Echocardiography. 23:164-171
Hypertrophic cardiomyopathy (HCM) is characterized by myocardial hypertrophy, fiber disarray, and fibrosis interfering with myocardial force generation and relaxation. Because conventional Doppler echocardiographic methods inadequately assess diastol
Publikováno v:
Journal of the American College of Cardiology. 54:191-200
Dynamic obstruction to left ventricular (LV) outflow was recognized from the earliest (50 years ago) clinical descriptions of hypertrophic cardiomyopathy (HCM) and has proved to be a complex phenomenon unique in many respects, as well as arguably the
Autor:
E. Douglas Wigle, Harry Rakowski, Shemy Carasso, Meredith Linghorne, Leonard Schwartz, Hua Yang, Michal Jamorski, Mani A. Vannan, Anna Woo
Publikováno v:
Journal of the American Society of Echocardiography. 21:493-499
We hypothesized that the time course of left ventricular (LV) outflow tract gradient reduction during septal ethanol ablation for patients with symptomatic hypertrophic obstructive cardiomyopathy is related to changes in myocardial mechanics. A total
Autor:
Richard Choi, Harry Rakowski, Anna Woo, Anthony Ralph-Edwards, William G. Williams, Samuel Siu, Katie Fedwick, E. Douglas Wigle, Evelyn Rozenblyum
Publikováno v:
Circulation. 111:2033-2041
Background— Surgical myectomy has been the standard treatment for patients with drug-refractory obstructive hypertrophic cardiomyopathy. The clinical and echocardiographic predictors of long-term survival and freedom from cardiovascular morbidity a
Autor:
Gabriel Gregoratos, Jaap W. Deckers, Jonathan R. Lindner, Angeles Alonso-Garcia, Sigmund Silber, Christine E. Seidman, Alexander Parkhomenko, Cynthia M. Tracy, Judith S. Hochman, Peter G. Danias, Sanjiv Kaul, Lukas Kappenberger, Eric R. Bates, Richard S. Schofield, Guy De Backer, Gerald M. Pohost, Silvia G. Priori, Mark A. Hlatky, Markus Flather, Ali Oto, Folkert J. Ten Cate, E. Douglas Wigle, William L. Winters, Horst J. Kuhn, Pravin M. Shah, Werner Klein, Adam Torbicki, Barry J. Maron, Robert A. O'Rourke, Carina Blomström-Lundqvist, William H. Spencer, Jonathan Abrams, William J. McKenna, Jaromír Hradec, Robert A. Vogel, Robert C. Lichtenberg, Bruce R. Brodie, Paolo Spirito, Gordon K. Danielson
Publikováno v:
Journal of the American College of Cardiology. 42:1687-1713
Preamble......1688 Introduction......1688 General Considerations and Perspectives......1688 Nomenclature, Definitions, and Clinical Diagnosis......1689 Obstruction to LV Outflow......1689 Genetics and Molecular Diagnosis......1690 General Considerati
Autor:
Mitsuhiro Kamisago, Sapna D. Sharma, Steven R. DePalma, Scott Solomon, Pankaj Sharma, Barbara McDonough, Leslie Smoot, Mary P. Mullen, Paul K. Woolf, E. Douglas Wigle, J.G. Seidman, John Jarcho, Lawrence R. Shapiro, Christine E. Seidman
Publikováno v:
New England Journal of Medicine. 343:1688-1696
The molecular basis of idiopathic dilated cardiomyopathy, a primary myocardial disorder that results in reduced contractile function, is largely unknown. Some cases of familial dilated cardiomyopathy are caused by mutations in cardiac cytoskeletal pr
Autor:
Harry Rakowski, Eric H.C. Yu, Ahmad S. Omran, E. Douglas Wigle, William G. Williams, Samuel C. Siu
Publikováno v:
Journal of the American College of Cardiology. 36:2219-2225
OBJECTIVESThis study examined: 1) the impact of myectomy on postoperative mitral regurgitation (MR) and 2) the association between the severity of MR and the left ventricular outflow tract (LVOT) gradient.BACKGROUNDFor patients with hypertrophic obst