Zobrazeno 1 - 10
of 285
pro vyhledávání: '"E. Dorn"'
Autor:
Jennifer M. Petrosino, Scott A. Hinger, Volha A. Golubeva, Juan M. Barajas, Lisa E. Dorn, Chitra C. Iyer, Hui-Lung Sun, W. David Arnold, Chuan He, Federica Accornero
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Muscle undergoes hypertrophy and atrophy in response to physiological stimuli or in pathological conditions, which is partially controlled through altered gene expression. Here the authors report that m6A methyltransferase METTL3 and mRNA m6A post-tr
Externí odkaz:
https://doaj.org/article/1a052b16c28446cb99698ffe0e5759b1
Autor:
Colton R Martens, Lisa E Dorn, Adam D Kenney, Shyam S Bansal, Jacob S Yount, Federica Accornero
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010342 (2022)
Viral infection of the heart is a common but underappreciated cause of heart failure. Viruses can cause direct cardiac damage by lysing infected cardiomyocytes. Inflammatory immune responses that limit viral replication can also indirectly cause dama
Externí odkaz:
https://doaj.org/article/8c6a49a89578411b9e205be4566e928a
Autor:
Nadine Norton, Katelyn A. Bruno, Damian N. Di Florio, Emily R. Whelan, Anneliese R. Hill, Andrea Carolina Morales-Lara, Anna A. Mease, John M. Sousou, Jose A. Malavet, Lauren E. Dorn, Gary R. Salomon, Logan P. Macomb, Sami Khatib, Zacharias P. Anastasiadis, Brian M. Necela, Molly M. McGuire, Presley G. Giresi, Archana Kotha, Danielle J. Beetler, Raegan M. Weil, Carolyn K. Landolfo, DeLisa Fairweather
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Background: Doxorubicin is a widely used and effective chemotherapy, but the major limiting side effect is cardiomyopathy which in some patients leads to congestive heart failure. Genetic variants in TRPC6 have been associated with the development of
Externí odkaz:
https://doaj.org/article/85bee347666346f7a718979912b458e6
Autor:
Jacob Z. Longenecker, Jennifer M. Petrosino, Colton R. Martens, Scott A. Hinger, Charlotte J. Royer, Lisa E. Dorn, Daniel A. Branch, Joan Serrano, Kristin I. Stanford, George A. Kyriazis, Kedryn K. Baskin, Federica Accornero
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101343- (2021)
Regulation of organismal homeostasis in response to nutrient availability is a vital physiological process that involves inter-organ communication. Understanding the mechanisms controlling systemic cross-talk for the maintenance of metabolic health i
Externí odkaz:
https://doaj.org/article/2b209f5d12c04303857000b576c46e62
Autor:
Zachary M. Howard, Lisa E. Dorn, Jeovanna Lowe, Megan D. Gertzen, Pierce Ciccone, Neha Rastogi, Guy L. Odom, Federica Accornero, Jeffrey S. Chamberlain, Jill A. Rafael-Fortney
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
Gene replacement for Duchenne muscular dystrophy (DMD) with micro-dystrophins has entered clinical trials, but efficacy in preventing heart failure is unknown. Although most patients with DMD die from heart failure, cardiomyopathy is undetectable unt
Externí odkaz:
https://doaj.org/article/edf8afa3bfcf4133a3ecce62112683f8
Autor:
Arden B. Piepho, Jeovanna Lowe, Laurel R. Cumby, Lisa E. Dorn, Dana M. Lake, Neha Rastogi, Megan D. Gertzen, Sarah L. Sturgill, Guy L. Odom, Mark T. Ziolo, Federica Accornero, Jeffrey S. Chamberlain, Jill A. Rafael-Fortney
Publikováno v:
Molecular Therapy - Methods & Clinical Development. 28:344-354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7f05674fe194d3e605748139be30ace
https://doi.org/10.1016/j.omtm.2023.02.001
https://doi.org/10.1016/j.omtm.2023.02.001
Autor:
Sunhee Hwang, Karen Mruk, Simin Rahighi, Andrew G. Raub, Che-Hong Chen, Lisa E. Dorn, Naoki Horikoshi, Soichi Wakatsuki, James K. Chen, Daria Mochly-Rosen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Glucose-6-phosphate dehydrogenase (G6PD) deficiency provides insufficient protection from oxidative stress, contributing to diverse human pathologies. Here, the authors identify a small molecule that increases the activity and/or stability of mutant
Externí odkaz:
https://doaj.org/article/1d179241d985451cb9ca3ac72357b58a
Publikováno v:
Heart Rhythm. 20:718-719
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e11ed8bfef490b62b74cac03641b13c
https://doi.org/10.1016/j.hrthm.2023.02.013
https://doi.org/10.1016/j.hrthm.2023.02.013
Autor:
Ann-Kristin Folkerts, Miriam E. Dorn, Mandy Roheger, Marco Maassen, Janneke Koerts, Oliver Tucha, Mareike Altgassen, Alexander T. Sack, Diede Smit, Lena Haarmann, Elke Kalbe
Publikováno v:
Parkinson's Disease, Vol 2018 (2018)
Background. While the efficacy of cognitive stimulation (CS) has been demonstrated in patients with dementia, no study has included patients with Parkinson’s disease dementia (PDD). Objective. For the first time, this randomized crossover pilot stu
Externí odkaz:
https://doaj.org/article/108fabb9b4ae493f8bd528592902b12d
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