Zobrazeno 1 - 10
of 13
pro vyhledávání: '"E. Dinant Kroese"'
Autor:
Harrie Buist, E. Dinant Kroese, Eugene P. van Someren, Danyel Jennen, Rob Stierum, Jack W. T. E. Vogels
Publikováno v:
Handbook of Biomarkers and Precision Medicine ISBN: 9780429202872
This chapter describes the development of such a generic data management and data integration platform: Data-warehouse Infrastructure for Algorithms, Models and Ontologies toward Novel Design and Safety (DIAMONDS). The DIAMONDS platform consists of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20e3945e1fb0c077a3d96bd0e4eb69ad
https://doi.org/10.1201/9780429202872-7
https://doi.org/10.1201/9780429202872-7
Autor:
Jan van Benthem, Jan Willem van der Laan, Ruud Woutersen, Ans E. M. F. Soffers, E. Dinant Kroese, Mirjam Luijten, Cyrille Krul
Publikováno v:
Regulatory Toxicology and Pharmacology, 81, 242-249
Regulatory Toxicology and Pharmacology 81 (2016)
Regulatory Toxicology and Pharmacology 81 (2016)
Sub-chronic toxicity studies of 163 non-genotoxic chemicals were evaluated in order to predict the tumour outcome of 24-month rat carcinogenicity studies obtained from the EFSA and ToxRef databases. Hundred eleven of the 148 chemicals that did not in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5959c690d17e8ee32116523922a6bb2
https://research.wur.nl/en/publications/prediction-of-carcinogenic-potential-of-chemicals-using-repeated-
https://research.wur.nl/en/publications/prediction-of-carcinogenic-potential-of-chemicals-using-repeated-
Publikováno v:
Reproductive Toxicology. 31:558-561
In spite of extensive research in the area over many decades, there is still a shortage of accepted alternative testing methods in reproductive toxicology. Of the variety of alternative methods developed for reproductive toxicity testing not a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db27f053a719b0a266b3d362f0b04a04
https://doi.org/10.1016/j.reprotox.2011.02.012
https://doi.org/10.1016/j.reprotox.2011.02.012
Autor:
Aldert H. Piersma, Eduard Pauné, Inge Mangelsdorf, Bart van der Burg, Michael Schwarz, Daniel R. Dietrich, Eva Bay Wedebye, Joanna Jaworska, E. Dinant Kroese
Publikováno v:
Reproductive Toxicology, 10 p.
There is a great need for rapid testing strategies for reproductive toxicity testing, avoiding animal use. The EU Framework program 7 project ChemScreen aimed to fill this gap in a pragmatic manner preferably using validated existing tools and place
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6eecf5268db1d3e79d7010af747a29
http://resolver.tudelft.nl/uuid:6b53f9d7-807e-4141-8ad8-fa508207cd55
http://resolver.tudelft.nl/uuid:6b53f9d7-807e-4141-8ad8-fa508207cd55
Autor:
Aldert H. Piersma, Emiel Rorije, Sander C. van der Linden, Hai-Yen Man, Harrie Buist, B. Pieterse, Inge Mangelsdorf, Bart van der Burg, Andre Wolterbeek, Geertje Lewin, Barbara M.A. van Vugt-Lussenburg, E. Dinant Kroese
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 55
There is a great need for alternative testing methods for reproductive toxicants that are practical, fast, cost-effective and easy to interpret. Previously we followed a pragmatic approach using readily available tests, which was successful in predic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbce3bbd2db96b7b89a6ddba17894baf
https://pubmed.ncbi.nlm.nih.gov/25527862
https://pubmed.ncbi.nlm.nih.gov/25527862
Publikováno v:
Pharmacology & Toxicology, 6, 88, 331-341
This report provides guidance for using the dose-descriptor T25 from animal studies as a basis for quantitative risk characterisation of non-threshold carcinogens. T25 is presently used within the European Union for setting specific concentration lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0923ff67d6e63440441e70f308c738d9
https://doi.org/10.1034/j.1600-0773.2001.d01-126.x
https://doi.org/10.1034/j.1600-0773.2001.d01-126.x
Autor:
E. Dinant Kroese
Publikováno v:
Toxicology Letters. 180:S17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad8163af95d8d93f68041cfbd7d4cdb2
https://doi.org/10.1016/j.toxlet.2008.06.800
https://doi.org/10.1016/j.toxlet.2008.06.800
Publikováno v:
Carcinogenesis. 9:1953-1958
The ability of N-hydroxy-2-acetylaminofluorene (N-OH-AAF) to promote the appearance of gamma-glutamyltranspeptidase-positive (GGT+) foci initiated by diethylnitrosamine (DEN) was studied in a slightly modified Solt and Farber protocol. This protocol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a530b3140a62e03f121db3bcb79c6e
https://doi.org/10.1093/carcin/9.11.1953
https://doi.org/10.1093/carcin/9.11.1953
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