Zobrazeno 1 - 10
of 2 247
pro vyhledávání: '"E. Dickinson"'
Autor:
Taeyong Ahn, Gabrielle E. Largoza, Julia Younis, Mary E. Dickinson, Chih-Wei Hsu, Joshua D. Wythe
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103053- (2024)
Summary: Tissue clearing is an essential prerequisite for 3D volumetric imaging of larger tissues or organs. Here, we present a detailed protocol for optical, aqueous-based clearing of adult murine tissues using EZ Clear. We describe steps to ensure
Externí odkaz:
https://doaj.org/article/9322ef5749124732a8462233fa4d451f
Autor:
Emma R. Allanson, Sean Copson, Katrina Spilsbury, Sonya Criddle, Belinda Jennings, Dorota A. Doherty, Antonia M. Wong, Jan E. Dickinson
Publikováno v:
Reproductive, Female and Child Health, Vol 3, Iss 1, Pp n/a-n/a (2024)
Abstract Objective To provide data on maternal levels of estradiol and progesterone in the second trimester of pregnancy with a live foetus and those complicated by a spontaneous foetal demise. Methods Within a randomised trial to assess efficacy of
Externí odkaz:
https://doaj.org/article/6e59043b00f446e18af4806c963241ba
Autor:
Sally E. Dickinson, Prajakta Vaishampayan, Jana Jandova, Yuchen (Ella) Ai, Viktoria Kirschnerova, Tianshun Zhang, Valerie Calvert, Emanuel Petricoin, III, H-H. Sherry Chow, Chengcheng Hu, Denise Roe, Ann Bode, Clara Curiel-Lewandrowski, Georg T. Wondrak
Publikováno v:
JID Innovations, Vol 4, Iss 2, Pp 100255- (2024)
The immune checkpoint ligand PD-L1 has emerged as a molecular target for skin cancer therapy and might also hold promise for preventive intervention targeting solar UV light–induced skin damage. In this study, we have explored the role of PD-L1 in
Externí odkaz:
https://doaj.org/article/4873d63114f54bb08050d842cfda8f6a
Autor:
Kevin A. Peterson, Sam Khalouei, Nour Hanafi, Joshua A. Wood, Denise G. Lanza, Lauri G. Lintott, Brandon J. Willis, John R. Seavitt, Robert E. Braun, Mary E. Dickinson, Jacqueline K. White, K. C. Kent Lloyd, Jason D. Heaney, Stephen A. Murray, Arun Ramani, Lauryl M. J. Nutter
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Genome editing with CRISPR-associated (Cas) proteins holds exceptional promise for “correcting” variants causing genetic disease. To realize this promise, off-target genomic changes cannot occur during the editing process. Here, we use w
Externí odkaz:
https://doaj.org/article/f7798291f4934fd091966e0b3ee6f881
Autor:
E. Towler, S. S. Foks, A. L. Dugger, J. E. Dickinson, H. I. Essaid, D. Gochis, R. J. Viger, Y. Zhang
Publikováno v:
Hydrology and Earth System Sciences, Vol 27, Pp 1809-1825 (2023)
Because use of high-resolution hydrologic models is becoming more widespread and estimates are made over large domains, there is a pressing need for systematic evaluation of their performance. Most evaluation efforts to date have focused on smaller b
Externí odkaz:
https://doaj.org/article/7772823bd6814a5183b1c1beba778feb
Autor:
Justine M. Chee, Louise Lanoue, Dave Clary, Kendall Higgins, Lynette Bower, Ann Flenniken, Ruolin Guo, David J. Adams, Fatima Bosch, Robert E. Braun, Steve D. M. Brown, H.-J. Genie Chin, Mary E. Dickinson, Chih-Wei Hsu, Michael Dobbie, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D. Heaney, Yann Herault, Martin Hrabe de Angelis, Fabio Mammano, Lauryl M. J. Nutter, Helen Parkinson, Chuan Qin, Toshi Shiroishi, Radislav Sedlacek, J-K Seong, Ying Xu, The International Mouse Phenotyping Consortium, Brian Brooks, Colin McKerlie, K. C. Kent Lloyd, Henrik Westerberg, Ala Moshiri
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Microphthalmia, anophthalmia, and coloboma (MAC) spectrum disease encompasses a group of eye malformations which play a role in childhood visual impairment. Although the predominant cause of eye malformations is known to be herita
Externí odkaz:
https://doaj.org/article/f36d8250a6ce4896a0f38551711ec1ef
Autor:
Jonathan E. Dickinson, Jose Adalberto Dominguez Inzunza, Liliana Perez-Villa, Trevor G. Millar, Abhiram P. Pushparaj
Publikováno v:
Frontiers in Pain Research, Vol 4 (2023)
Brachial plexus nerve root avulsion results from complete separation of the nerve root from the spinal cord and is one of the most challenging types of neuropathic pain, coinciding with motor, sensory and autonomic deficits. The severe pain and typic
Externí odkaz:
https://doaj.org/article/e418f925f55c46dbbcc908b82bb50784
Autor:
Kendall Higgins, Bret A. Moore, Zorana Berberovic, Hibret A. Adissu, Mohammad Eskandarian, Ann M. Flenniken, Andy Shao, Denise M. Imai, Dave Clary, Louise Lanoue, Susan Newbigging, Lauryl M. J. Nutter, David J. Adams, Fatima Bosch, Robert E. Braun, Steve D. M. Brown, Mary E. Dickinson, Michael Dobbie, Paul Flicek, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D. Heaney, Yann Herault, Martin Hrabe de Angelis, Hsian-Jean Genie Chin, Fabio Mammano, Chuan Qin, Toshihiko Shiroishi, Radislav Sedlacek, J.-K. Seong, Ying Xu, The IMPC Consortium, K. C. Kent Lloyd, Colin McKerlie, Ala Moshiri
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract We searched a database of single-gene knockout (KO) mice produced by the International Mouse Phenotyping Consortium (IMPC) to identify candidate ciliopathy genes. We first screened for phenotypes in mouse lines with both ocular and renal or
Externí odkaz:
https://doaj.org/article/c0d5d5cc412449dba2430740f3a4e375
Autor:
Pilar Cacheiro, Carl Henrik Westerberg, Jesse Mager, Mary E. Dickinson, Lauryl M. J. Nutter, Violeta Muñoz-Fuentes, Chih-Wei Hsu, Ignatia B. Van den Veyver, Ann M. Flenniken, Colin McKerlie, Stephen A. Murray, Lydia Teboul, Jason D. Heaney, K. C. Kent Lloyd, Louise Lanoue, Robert E. Braun, Jacqueline K. White, Amie K. Creighton, Valerie Laurin, Ruolin Guo, Dawei Qu, Sara Wells, James Cleak, Rosie Bunton-Stasyshyn, Michelle Stewart, Jackie Harrisson, Jeremy Mason, Hamed Haseli Mashhadi, Helen Parkinson, Ann-Marie Mallon, International Mouse Phenotyping Consortium, Genomics England Research Consortium, Damian Smedley
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-20 (2022)
Abstract Background The diagnostic rate of Mendelian disorders in sequencing studies continues to increase, along with the pace of novel disease gene discovery. However, variant interpretation in novel genes not currently associated with disease is p
Externí odkaz:
https://doaj.org/article/412d46fbccfd45569d9db0ede072d45d
Autor:
Chih-Wei Hsu, Juan Cerda III, Jason M Kirk, Williamson D Turner, Tara L Rasmussen, Carlos P Flores Suarez, Mary E Dickinson, Joshua D Wythe
Publikováno v:
eLife, Vol 11 (2022)
Tissue clearing for whole organ cell profiling has revolutionized biology and imaging for exploration of organs in three-dimensional space without compromising tissue architecture. But complicated, laborious procedures, or expensive equipment, as wel
Externí odkaz:
https://doaj.org/article/db91eaefe7cc4e39886bcb09a8d82078