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Publikováno v:
Clinical Endocrinology. 82:76-83
SummaryObjectives We postulated the mechanism for the association between angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and insulin sensitivity might relate to changes in blood flow regulation. We studied the associat
Publikováno v:
Diabetes Care. 26:2256-2260
OBJECTIVE—To compare the effectiveness of a nurse-led hypertension clinic with conventional community care in general practice in the management of uncontrolled hypertension in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS—We studied
Effect of salt-loading on blood pressure, insulin sensitivity and limb blood flow in normal subjects
Publikováno v:
Clinical Science. 95:157-164
1.The aim of this study was to determine the effects of high (220 ;mmol/day) and low (40 ;mmol/day) salt intake for 6 days on blood pressure, leg blood flow and insulin sensitivity in 18 ;healthy normotensive subjects. 2.Twenty-four-hour ambulatory b
Publikováno v:
Metabolism. 47:637-643
In non-insulin-dependent diabetes mellitus (NIDDM), cardiovascular risk factors improve during treatment, but whether insulin (I) differs from sulfonylurea (SU) therapy is unclear. To separate the contributions of improved diabetic control versus tre
Publikováno v:
Clinical Drug Investigation. 16:303-317
This study aimed to compare the effects of glimepiride and glibenclamide on glycaemic control and a range of risk factors for ischaemic heart disease (IHD), including concentrations of insulin-like molecules.A double-blind, placebo-controlled, random
Publikováno v:
Metabolism. 45:961-965
Association have been described between cardiovascular risk factors and abnormalities of both sodium-lithium countertransport (SLC) and sodium-hydrogen ion exchange in subjects with insulin-dependent diabetes mellitus. The data in subjects with non-i
Publikováno v:
Metabolism. 45:652-657
Glucose intolerance is a common consequence of transfusion therapy in patients with thalassemia major (TM), but the relative contribution of pancreatic damage and insulin resistance to glucose intolerance is unclear. We have investigated oral (OGTT)
Publikováno v:
Diabetic Medicine. 12:904-910
A population-based cross-sectional survey was carried out to study potential environmental risk factors contributing to diabetes and cardiovascular risk in the same homogeneous group in the United Kingdom and in Dar es Salaam, Tanzania. In Dar es Sal
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 80:455-460
Platelets take up and store noradrenaline and adrenaline in proportion to plasma concentrations and may, therefore, provide an integrated index of sympathoadrenomedullary arousal. Plasma and platelet catecholamine concentrations were measured in 290