Zobrazeno 1 - 10
of 39
pro vyhledávání: '"E. David Murray"'
Publikováno v:
Chirality. 16:379-387
Information about the potential and extent of bioinversion of chiral drugs in laboratory animal species and humans is critical to the interpretation of preclinical pharm-tox studies with these drugs. Unlike in the dog, guinea pig, and rabbit, in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d496d995e62d75d0971c0b2170e6b9
https://doi.org/10.1002/chir.20053
https://doi.org/10.1002/chir.20053
Autor:
Vijendra K. Singh, Margaret E. Gnegy, S. P. Gupta, R. Leurs, R. C. Vollinga, H. Timmerman, Ray W. Fuller, Nissim Claude Cohen, Vincenzo Tschinke, Elaine J. Benaksas, E. David Murray, William J. Wechter, Indra Dwivedy, Suprabhat Ray
Volume 45 of'Progress in Drug Research'contains eight reviews and the various indexes which facilitate its use and establish the connection with the previous volumes. The articles in this volume deal with neuro peptides as native immune modulators,
Autor:
Karina M. Gibson, E. David Murray, John D. Mccracken, Darko Kantoci, Douglas D. Leipold, David D. Quiggle, William J. Wechter
Publikováno v:
Life Sciences. 66:745-753
Our previous studies with the mouse model of familial adenomatous polyposis (FAP), C57BL/6J-APCMin/+ or Min mouse, demonstrated the optimal dose for adenoma reduction with R-flurbiprofen was 10 mg/kg/day as an undivided dose. Divided doses exhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605a64167b043b8147ed3a169c7444de
https://doi.org/10.1016/s0024-3205(99)00645-1
https://doi.org/10.1016/s0024-3205(99)00645-1
Autor:
E. David Murray, Youjiang Liu, Darko Kantoci, Resa L. Chase, David D. Quiggle, William J. Wechter, John D. Mccracken, Yoshimitzu Mineyama
Publikováno v:
The Journal of Clinical Pharmacology. 36:540-545
Nonsteroidal antiinflammatory drugs (NSAIDs) are recognized for inhibiting growth of colon tumors in animal models, and for reducing the risk of colon cancer in humans. The mechanisms involved have not been established, but are thought to be related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b4c9759efa7d110e3291d2a1113e7d
https://doi.org/10.1002/j.1552-4604.1996.tb05043.x
https://doi.org/10.1002/j.1552-4604.1996.tb05043.x
Publikováno v:
Chirality. 6:457-459
The route of administration of the NSAID, flurbiprofen (sq vs. po) resulted in positive and negative results respectively with regard to enhanced cancellous and cortical bone accumulation in the immature rat. This pharmacokinetic study was an effort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd311f706d578e2b0f4c55e23a7dfc4a
https://doi.org/10.1002/chir.530060602
https://doi.org/10.1002/chir.530060602
Autor:
Vijendra K. Singh, Margaret E. Gnegy, S. P. Gupta, R. Leurs, R. C. Vollinga, H. Timmerman, Ray W. Fuller, Nissim Claude Cohen, Vincenzo Tschinke, Elaine J. Benaksas, E. David Murray, William J. Wechter, Indra Dwivedy, Suprabhat Ray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c38044fa93f3476c9b2fe55dbbbec2bf
https://doi.org/10.1007/978-3-0348-7164-8
https://doi.org/10.1007/978-3-0348-7164-8
Autor:
Barry H. Levine, Sally A. DeWind, Tim Pham, Derin C. D'Amico, Darko Kantoci, E. David Murray, William J. Wechter, Michael E. Jung, Annette E. Bigornia, James G. King
Publikováno v:
Life sciences. 57(23)
A low molecular weight endogenous substance believed to be responsible for extracellular fluid homeostasis in mammals has been sought for many years. Our goal is to isolate and structurally characterize this putative {open_quotes}natriuretic hormone{
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b9b15d5a3c553b1009c33cc0febd62
https://pubmed.ncbi.nlm.nih.gov/7475967
https://pubmed.ncbi.nlm.nih.gov/7475967
Autor:
Rita Giebel, A. E. Bigornia, Tim Pham, Cynthia L. Rodgers, Elaine J. Benaksas, E. David Murray, Elaine S. Brubacher, Sally A. Dewind, William J. Wechter
Publikováno v:
Life sciences. 52(12)
It is our purpose to isolate and characterize the putative “Natriuretic Hormone”, ostensibly responsible for ECF homeostasis, as well as identify endonenous pressors and compounds that induce prolonged natriuresis; we report here our initial prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed738cb46d323efb96d596f80c5f47be
https://pubmed.ncbi.nlm.nih.gov/8383267
https://pubmed.ncbi.nlm.nih.gov/8383267
Autor:
Frank H. Ebetino, Darlene Z. Gabriel, Oleg Aleksiuk, William J. Wechter, Darko Kantoci, E. David Murray, Dan Borchard
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 147:3-3
Aminobisphosphonates have generated substantial interest recently for the treatment of bone diseases and as plant growth regulators, both alone and as a carrier for other drugs, because of the high affinity to the hydroxyapatite (HAP). We are investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28276fbe5c57e217950616a834498dea
https://doi.org/10.1080/10426509908053482
https://doi.org/10.1080/10426509908053482
Autor:
E. David Murray
Publikováno v:
Proteins ISBN: 9781461290018
Protein carboxyl methyltransferases from human erythrocytes and bovine brain catalyze the methylation of abnormal aspartyl residues in cellular proteins and synthetic peptides (1–2). These sites of methylation appear to include the β-carboxyl grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4efc45cfd172819dbbc8a44130758d23
https://doi.org/10.1007/978-1-4613-1787-6_19
https://doi.org/10.1007/978-1-4613-1787-6_19