Zobrazeno 1 - 10
of 24
pro vyhledávání: '"E. D. Nikolskaya"'
Publikováno v:
Антибиотики и Химиотерапия, Vol 68, Iss 7-8, Pp 53-61 (2023)
The combination of two or more medications is increasingly more common in the development of new treatment guidelines for common diseases. Thus, the use of combinations of histone deacetylase inhibitors with chemotherapeutic agents is a current trend
Externí odkaz:
https://doaj.org/article/410adb18181f478d9aec662d05427646
Autor:
M. B. Sokol, N. G. Yabbarov, M. R. Mollaeva, M. V. Chirkina (Fomicheva), V. Yu. Balaban'yan, E. D. Nikolskaya
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 10, Iss 4, Pp 81-88 (2021)
Introduction. The use of the anticancer drug paclitaxel is limited due to its high toxicity and lipophilicity. A new polymer composition of paclitaxel has been proposed, which provides targeted transport of the drug into tumor cells and improves its
Externí odkaz:
https://doaj.org/article/c2535d291c584367a46a97839190f2b5
Autor:
E. D. Nikolskaya, O. A. Zhunina, M. B. Sokol, M. V. Fomicheva, N. V. Gukasova, E. A. Vorontsov, N. G. Yabbarov, O. G. Tereshchenko, E. S. Severin
Publikováno v:
Антибиотики и Химиотерапия, Vol 62, Iss 3-4, Pp 18-24 (2020)
The polymeric form ofjosamycin was developed by loading of the antibiotic into spherical submicron particles made of poly(DL- lactide-co-glycolide) (PLGA 50/50) by double emulsion method. The average diameter and zeta-potential of particles synthesiz
Externí odkaz:
https://doaj.org/article/03d81204b53b4cd7a4eec21b467c29f9
Autor:
M. D. Sapelnikov, E. D. Nikolskaya, N. B. Morozova, E. A. Plotnikova, A. V. Efremenko, A. V. Panov, M. A. Grin, R. I. Yakubovskaya
Publikováno v:
Biomedical Photonics, Vol 8, Iss 1, Pp 4-17 (2019)
The article describes the process of developing a technology for producing nanoparticles based on a copolymer of lactic and glycolic acids (PLGA) containing dipropoxybacteriopurpurinimide (DPBPI) for photodynamic therapy of malignant tumors of variou
Externí odkaz:
https://doaj.org/article/00b82731ba19487da84c9b1013af01fc
Autor:
N. G. Yabbarov, M. D. Mollaev, A. I. Zabolotskii, D. A. Mazalev, N. V. Gorokhovets, M. B. Sokol, M. R. Mollaeva, M. V. Fomicheva, A. B. Pshenichnikova, E. D. Nikolskaya
Publikováno v:
Applied Biochemistry and Microbiology. 58:899-908
Autor:
N. G. Yabbarov, R. V. Petrov, E. D. Nikolskaya, O. A. Zhunina, M. B. Sokol, M. V. Fomicheva, M. R. Faustova
Publikováno v:
Russian Chemical Bulletin. 69:793-803
New high-molecular-weight contrast agents based on polyamidoamine (PAMAM) dendrimers for targeted imaging of malignant tumors characterized by overexpression of human epidermal growth factor receptor (EGFR) and human alpha-fetoprotein receptor (RECAF
Autor:
N. G. Yabbarov, M. D. Mollaev, A. I. Zabolotsky, A. V. Lobanov, M. V. Fomicheva, O. A. Zhunina, E. D. Nikolskaya, M. B. Sokol, V. I. Schvets, M. R. Faustova
Publikováno v:
Russian Chemical Bulletin. 68:2216-2224
Reactive oxygen species are generated by the redox reaction involving metalloporphyrin and ascorbic acid (AA) and lead to oxidative stress followed by cancer cell death. Polymer particles based on the copolymer of lactic and glycolic acid (PLGA) cont
Autor:
M. R. Faustova, O. A. Zhunina, N. G. Yabbarov, M. D. Mollaev, E. S. Severin, Neonila V. Gorokhovets, Irina A. Zamulaeva, A. Zabolotsky, M. Sokol, E. D. Nikolskaya
Publikováno v:
International Journal of Pharmaceutics. 559:138-146
Despite the presence of a variety of modern anticancer drugs at the market, doxorubicin (Dox) is still widely used in antineoplastic therapy, although its administration causes severe side effects. To enhance specific activity of such molecules, vari
Formulation of perspective hepatoprotector polymeric forms based on silybin and ursodeoxycholic acid
Autor:
M. B. Sokol, E. D. Nikolskaya, V. V. Zavarzina, N. V. Gukasova, N. G. Yabbarov, E. S. Severin, O. G. Tereshchenko, M. V. Fomicheva, O. A. Zhunina, E. V. Zubkov
Publikováno v:
Russian Chemical Bulletin. 67:2290-2296
Silybin (Slb) and ursodeoxycholic acid (UDCA) are hepatoprotectors used in the pathogenetic therapy of liver and biliary tract. However, low bioavailability of these drugs restricts their application. In order to solve this problem, Slb and UDCA were
Autor:
E. D. Nikolskaya, M. Fomicheva, M. Sokol, V. A. Zenin, M. Mollaeva, V. I. Popenko, M. D. Mollaev, A. Zabolotsky, S. Kuznetsov, I. F. Seregina, N. G. Yabbarov
Publikováno v:
Annales pharmaceutiques francaises. 79(5)
Summary Objectives The goal of this study was to develop sample preparation method and validate the HPLC method for precise determination of paclitaxel (Ptx) in PLGA submicron particles conjugated with protein vector molecule. Methods Ptx loaded PLGA