Zobrazeno 1 - 10
of 33
pro vyhledávání: '"E. D. Murphey"'
Autor:
E. D. Murphey
Publikováno v:
Topics in Companion Animal Medicine. 37:100361
The AVMA Animal Health Studies Database (AAHSD, www.avma.org/findvetstudies ) was established as a tool for investigators conducting prospective veterinary clinical studies. Investigators may use the database to list studies recruiting for patients a
Autor:
E. D. Murphey
Publikováno v:
Microbes and Infection. 14:35-42
When mice are subjected to a Pseudomonas aeruginosa challenge 5 days after cecal ligation and puncture (CLP), clearance of the Pseudomonas is diminished when compared to sham mice. The object of this study was to determine which component(s) of CLP c
Publikováno v:
Scopus-Elsevier
Publikováno v:
Critical Care Medicine. 36:3067-3073
Objective To determine whether tolerance and enhancement of innate immune function can be induced by the Gram-positive cell wall component peptidoglycan. Design Controlled, in vivo laboratory study. Subjects Male mice, 8-12 wks (C57BL6/J; C3H/HeJ; B6
Publikováno v:
Shock. 29:512-518
We studied the effects of tolerance induced by Escherichia coli-derived LPS on the innate immune response to a subsequent Staphylococcus aureus bacterial challenge. LPS tolerance was induced in wild-type mice by either intraperitoneal or intravenous
Autor:
Victor T. Enoh, Cheng Y. Lin, Tracy Toliver-Kinsky, Scott H. Lin, E. D. Murphey, Edward R. Sherwood, Tushar K. Varma
Publikováno v:
Shock. 27:507-519
The present study was undertaken to determine whether the mice depleted of alphabeta or gammadelta T cells show resistance to acute polymicrobial sepsis caused by cecal ligation and puncture (CLP). T-cell receptor beta knockout (betaTCRKO) and T-cell
Autor:
Zhiyu Huang, Tracy Toliver-Kinsky, Edward R. Sherwood, E. D. Murphey, Tushar K. Varma, Weihua Cui, Megan Durham, Cheng Y. Lin
Publikováno v:
Infection and Immunity. 73:7340-7347
Endotoxin (lipopolysaccharide [LPS]) tolerance is an altered state of immunity caused by prior exposure to LPS, in which production of many cytokines, including gamma interferon (IFN-γ) and interleukin-12 (IL-12), are reduced but secretion of the an
Publikováno v:
Laboratory Investigation. 84:1655-1665
We previously showed that beta 2 microglobulin knockout mice depleted of NK cells by treatment with anti-asialoGM1 (beta2MKO/alphaAsGM1 mice) are resistant to sepsis caused by cecal ligation and puncture (CLP). beta2MKO mice possess multiple immunolo
Autor:
Daniel L. Traber, E. D. Murphey
Publikováno v:
Critical Care Medicine. 29:1761-1766
Objective Tumor necrosis factor (TNF)-alpha administration in large amounts can induce a state of shock similar to that observed in patients suffering from septic shock. Small doses of TNF-alpha induce only mild, transient hemodynamic alterations and
Autor:
E. D. Murphey, Stephen B. Adams, Alan J. Ruggles, Elizabeth M. Santschi, Robert K. Schneider, John A. Stick
Publikováno v:
Journal of the American Veterinary Medical Association. 216:1949-1954
Objective—To determine clinical features of horses with a slab fracture of the central or third tarsal bone and to report outcome of horses in which treatment did not include surgery. Design—Retrospective study. Animals—25 horses (14 Standardbr