Zobrazeno 1 - 10
of 40
pro vyhledávání: '"E. D. Korchinski"'
Publikováno v:
Pharmaceutical Research. 18:1185-1189
Purpose. To test the hypothesis that the pharmacokinetics of d-meth- ylphenidate (d-MPH) would be altered by food ingested before administration of an immediate release formulation (dl-MPH- IR) but not when food is ingested before a slow release form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f0329d6df91831df17a648b29b64907
https://doi.org/10.1023/a:1010987212724
https://doi.org/10.1023/a:1010987212724
Publikováno v:
Canadian family physician Medecin de famille canadien. 22
This study was conducted to examine the characteristics of 'initial visits' by patients, contrasted with 'average visits', to discover what is needed to establish a satisfactory patient-physician relationship leading to long term continuous care.In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0da2db81e6cc146a145b2ed3c31b8089
https://pubmed.ncbi.nlm.nih.gov/21308071
https://pubmed.ncbi.nlm.nih.gov/21308071
Autor:
John W. Hubbard, Edward M. Hawes, Manickam Aravagiri, Kamal K. Midha, Gordon McKay, E. D. Korchinski, Stephen R. Marder
Publikováno v:
British Journal of Psychiatry. 163:19-24
Whereas some metabolites of antipsychotic drugs are psychoactive and contribute to clinical improvement, recent studies have provided evidence that certain metabolites contribute to side-effects which can be disabling enough to negate clinical improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0555a3c9cd1088b4cd4285767ce6aec
https://doi.org/10.1192/s0007125000292556
https://doi.org/10.1192/s0007125000292556
Publikováno v:
European Journal of Clinical Pharmacology. 45:563-569
A study was carried out in 11 healthy young men to investigate the pharmacokinetics of chlorpromazine (CPZ) after a bolus intravenous (IV) dose (10 mg) and three single oral doses (25, 50 and 100 mg), with a washout period of two weeks between doses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1ac72954e1c5148a70345092588168
https://doi.org/10.1007/bf00315316
https://doi.org/10.1007/bf00315316
Publikováno v:
Xenobiotica. 23:1059-1074
1. The metabolism of thioridazine was studied in adult male volunteers, female rat and female dog after oral administration of 50 mg, 20 mg/kg and 100 mg over 30 h, respectively. 2. Metabolites in organic extracts of the urine obtained from each spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df30046f5fb368fdeff6c580194df8e
https://doi.org/10.3109/00498259309059422
https://doi.org/10.3109/00498259309059422
Publikováno v:
Xenobiotica. 23:27-36
1. The metabolism of sulforidazine was studied in female dogs and adult male humans after oral administration of 37.5 mg and 25.0 mg, respectively. 2. Metabolites in organic extracts of dog urine were separated by h.p.l.c. and individually collected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2989653aaa8844f3b289cd51510d25
https://doi.org/10.3109/00498259309059359
https://doi.org/10.3109/00498259309059359
Publikováno v:
Pharmaceutical Research. 10:14-21
A definitive enantioselective pharmacokinetic evaluation of dl-threo-methylphenidate (MPH) was carried out in 11 healthy volunteers, all of whom received, in a randomized crossover design, three oral administrations of MPH: immediate release (IR), sl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03ae9c323223f0c94969d167586decbd
https://doi.org/10.1023/a:1018956526016
https://doi.org/10.1023/a:1018956526016
Autor:
John W. Hubbard, Kamal K. Midha, R. Schwede, T. Gurnsey, Edward M. Hawes, J.K. Cooper, Gordon McKay, E. D. Korchinski
Publikováno v:
European Journal of Clinical Pharmacology. 42:539-544
Commercial preparations of the tricyclic anti-depressant doxepin contain 15% of the more active cis-doxepin and 85% of the trans-isomer. The single dose pharmacokinetics of doxepin and its major metabolite N-desmethyldoxepin were examined in 30 healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ebddff8bf1e8f7b492f2b0b1c0dc37
https://doi.org/10.1007/bf00314865
https://doi.org/10.1007/bf00314865
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 15:213-220
1. Two pilot studies were carried out to investigate the enantioselective pharmacokinetics of methylphenidate (MPH) in children with attention deficit-hyperactivity disorder (ADHD). A more definitive study, which included administration of an intrave
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed0795a901c1254ff93f5f600670ffd
https://doi.org/10.1016/0278-5846(91)90083-d
https://doi.org/10.1016/0278-5846(91)90083-d
Publikováno v:
European Journal of Clinical Pharmacology. 41:471-474
Healthy male volunteers (n = 13) took a single oral dose of 60.3 mg of methoxyphenamine HCl with and without prior administration of either quinidine (250 mg as bisulphate salt) or its diastereomer quinine (300 mg as sulphate salt). Methoxyphenamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a81e2dc06168bdd17cd3bf6ef4c329e
https://doi.org/10.1007/bf00626372
https://doi.org/10.1007/bf00626372