P-563 The effect of embryo culture time on concordance rates between invasive and non-invasive preimplantation genetic testing for aneuploidies (niPGT-A) in spent culture media (SCM) analysis

Autor: A Biricik, V Bianchi, F Lecciso, M Surdo, I Bavaro, M Manno, V Saino, P Timperi, E Cotroneo, L Gigante, L Diano, F Spinella

Publikováno v: Human Reproduction. 37

Study question To evaluate different embryo culture times (day5 versus day6) to understand the ideal time-frame for the performance of concordance analysis between invasive and non-invasive PGT-A(niPGT-A) Summary answer Different levels of ploidy con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67db74960f605545a5e45df1f646fc91
https://doi.org/10.1093/humrep/deac107.520

Human Lung Tissue Transcriptome: Influence of Sex and Age.

Autor: Matteo Dugo, Chiara E Cotroneo, Emilie Lavoie-Charland, Matteo Incarbone, Luigi Santambrogio, Lorenzo Rosso, Maarten van den Berge, David Nickle, Peter D Paré, Yohan Bossé, Tommaso A Dragani, Francesca Colombo

Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0167460 (2016)

Sex and age strongly influence the pathophysiology of human lungs, but scarce information is available about their effects on pulmonary gene expression.We followed a discovery-validation strategy to identify sex- and age-related transcriptional diffe

Externí odkaz: https://doaj.org/article/730f9ecf9f5c484a9c0bc521d0c1e3c9

Lung expression of genes encoding SARS-CoV-2 cell entry molecules and antiviral restriction factors: interindividual differences are associated with age and germline variants

Autor: Tommaso A. Dragani, Francesca Colombo, Chiara E. Cotroneo, Nunzia Mangano

Germline variants in genes involved in SARS-CoV-2 cell entry (i.e. ACE2 and TMPRSS2) may influence the susceptibility to infection, as may polymorphisms in genes involved in the innate host response to viruses (e.g. APOBEC3 family). We searched for p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f0c003af884499b9c66fd571b8b7c2c
https://doi.org/10.1101/2020.06.24.168534

Expression quantitative trait analysis reveals fine germline transcript regulation in mouse lung tumors

Autor: Angela Pettinicchio, Tommaso A. Dragani, Francesca Colombo, Loris De Cecco, Daniele Lecis, Alice Dassano, Giacomo Manenti, Matteo Dugo, Chiara E. Cotroneo

Publikováno v: Cancer letters
375 (2016): 221–230. doi:10.1016/j.canlet.2016.02.054
info:cnr-pdr/source/autori:Cotroneo, Chiara E.; Dassano, Alice; Colombo, Francesca; Pettinicchio, Angela; Lecis, Daniele; Dugo, Matteo; De Cecco, Loris; Dragani, Tommaso A.; Manenti, Giacomo/titolo:Expression quantitative trait analysis reveals fine germline transcript regulation in mouse lung tumors/doi:10.1016%2Fj.canlet.2016.02.054/rivista:Cancer letters (Print)/anno:2016/pagina_da:221/pagina_a:230/intervallo_pagine:221–230/volume:375

Gene expression modulates cellular functions in both physiologic and pathologic conditions. Herein, we carried out a genetic linkage study on the transcriptome of lung tumors induced by urethane in an (A/J x C57BL/6)F4 intercross population, whose in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa07d3a7e922f8619c1107a632ccc04
https://doi.org/10.1016/j.canlet.2016.02.054

Genetic susceptibility variants for lung cancer: replication study and assessment as expression quantitative trait loci

Autor: Lorena Citterio, Matteo Dugo, Chiara E. Cotroneo, Tommaso A. Dragani, Paolo Manunta, Matteo Incarbone, Francesca Colombo, Luigi Santambrogio, Simona Delli Carpini, Giulia Pintarelli, Antonella Galvan, Davide Tosi, Sara Noci

Publikováno v: Scientific reports (Nature Publishing Group) 7 (2017). doi:10.1038/srep42185
info:cnr-pdr/source/autori:Pintarelli, Giulia; Cotroneo, Chiara Elisabetta; Noci, Sara; Dugo, Matteo; Galvan, Antonella; Delli Carpini, Simona; Citterio, Lorena; Manunta, Paolo; Incarbone, Matteo; Tosi, Davide; Santambrogio, Luigi; Dragani, Tommaso A.; Colombo, Francesca/titolo:Genetic susceptibility variants for lung cancer: Replication study and assessment as expression quantitative trait loci/doi:10.1038%2Fsrep42185/rivista:Scientific reports (Nature Publishing Group)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:7
Scientific Reports

Many single nucleotide polymorphisms (SNPs) have been associated with lung cancer but lack confirmation and functional characterization. We retested the association of 56 candidate SNPs with lung adenocarcinoma risk and overall survival in a cohort o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a1745b4441c9921d688804c6802751
https://doi.org/10.1038/srep42185