Zobrazeno 1 - 10
of 322
pro vyhledávání: '"E. Clemmer"'
Publikováno v:
Molecules, Vol 27, Iss 18, p 6026 (2022)
Chondroitin sulfate (CS) and dermatan sulfate (DS) are found in nature linked to proteoglycans, most often as hybrid CS/DS chains. In the extracellular matrix, where they are highly expressed, CS/DS are involved in fundamental processes and various p
Externí odkaz:
https://doaj.org/article/a3bd29284a50442f850a3d2fb5b41076
Autor:
Lucas W. Henderson, Edie M. Sharon, Amit K. S. Gautam, Adam J. Anthony, Martin F. Jarrold, David H. Russell, Andreas Matouschek, David E. Clemmer
Publikováno v:
The Journal of Physical Chemistry Letters. :5014-5017
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed9d23d5714b6f1375a5929ab7c5ad19
https://doi.org/10.1021/acs.jpclett.3c01040
https://doi.org/10.1021/acs.jpclett.3c01040
Publikováno v:
Molecules, Vol 27, Iss 3, p 743 (2022)
Gangliosides (GGs) represent an important class of biomolecules associated with the central nervous system (CNS). In view of their special role at a CNS level, GGs are valuable diagnostic markers and prospective therapeutic agents. By ion mobility se
Externí odkaz:
https://doaj.org/article/0001028fdacb481aa02a320ab46c4fba
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33:1368-1376
Diketopiperazine (DKP) formation is an important degradation pathway for peptides and proteins. It can occur during synthesis and storage in either solution or the solid state. The kinetics of peptide cleavage through DKP formation have been analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30088284f3521bada6510e19772fe950
https://doi.org/10.1021/jasms.2c00037
https://doi.org/10.1021/jasms.2c00037
Publikováno v:
Annu Rev Biophys
The structures and conformational dynamics of proteins, protein complexes, and their noncovalent interactions with other molecules are controlled specifically by the Gibbs free energy (entropy and enthalpy) of the system. For some organisms, temperat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e7d2ee52aee6e0aa4dc252e738db40
https://doi.org/10.1146/annurev-biophys-102221-101121
https://doi.org/10.1146/annurev-biophys-102221-101121
Publikováno v:
Journal of Mass Spectrometry. 58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3de9866012f58259bda2f1000206563
https://doi.org/10.1002/jms.4908
https://doi.org/10.1002/jms.4908
Publikováno v:
Glycobiology
A substantial shortcoming of large-scale datasets is often the inability to easily represent and visualize key features. This problem becomes acute when considering the increasing technical ability to profile large numbers of glycopeptides and glycan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d649aeecc3d37f76e80a951992153d
https://doi.org/10.1093/glycob/cwab116
https://doi.org/10.1093/glycob/cwab116
Autor:
Daniel R. Fuller, Zhichao Zhang, David A. Hales, Christopher R. Conant, Shannon A. Raab, David E. Clemmer, Tarick J. El-Baba
Publikováno v:
The Journal of Physical Chemistry B. 125:8107-8116
Peptides with penultimate proline residues undergo trans → cis isomerization of the Phe1-Pro2 peptide bond followed by spontaneous bond cleavage at the Pro2-Xxx3 bond (where Xxx is another amino acid residue), leading to cleavage of the Pro2-Xxx3 b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f283d13d379476eefa025d2bd16162b
https://doi.org/10.1021/acs.jpcb.1c03515
https://doi.org/10.1021/acs.jpcb.1c03515
Autor:
Stephen J. Valentine, David H. Russell, David E. Clemmer, Arthur Laganowsky, Tarick J. El-Baba, Shannon A. Raab
Publikováno v:
J Am Soc Mass Spectrom
We present simple considerations of how differences in time scales of motions of protons, the lightest and fastest chemical moiety, and the much longer time scales associated with the dynamics of proteins, among the heaviest and slowest analytes, may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d953a6d70dc25a4e60c31f2a57a4d70e
https://doi.org/10.1021/jasms.1c00100
https://doi.org/10.1021/jasms.1c00100
Autor:
David H. Russell, Rachel P. Buckley, Tarick J. El-Baba, Jonathan C. Trinidad, Hengyao Niu, Christopher J. Brown, Shannon A. Raab, Arthur Laganowsky, Corinne A. Lutomski, David E. Clemmer, Daniel W. Woodall, Jiangchuan Shen, Martin F. Jarrold, Lucas W. Henderson
Publikováno v:
Anal Chem
The thermal stabilities of endogenous, intact proteins and protein assemblies in complex mixtures were characterized in parallel by means of variable-temperature electrospray ionization coupled to mass spectrometry (vT-ESI-MS). The method is demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b028340f8f0e589912acac1d66e0649
https://doi.org/10.1021/acs.analchem.1c00772
https://doi.org/10.1021/acs.analchem.1c00772