Zobrazeno 1 - 10
of 53
pro vyhledávání: '"E. Clarke Haley"'
Autor:
Patrick Lyden, Joseph Broderick, James Grotta, Thomas Kwiatkowski, Steven Levine, Michael Frankel, E. Clarke Haley, Barbara Tilley
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/f83b783aa979401c9f330e3c5d6e332e
Autor:
Julie Qidwai, E. Mark Haacke, Michael T. Froehler, Jan Claassen, Curtis G. Benesch, Arthur W. Toga, Ashutosh P Jadhav, Howard P. Levy, Shlee S. Song, Kim Magee, Robert N. Sawyer, Marilyn M Rymer, Michael A. Rippee, Archana Hinduja, Thomas P. Davis, Mark Johnson, Merit Cudkowicz, Michel T. Torbey, Miller Fawaz, Kent E. Pryor, Peter M Hannon, Patrick D. Lyden, Opeolu Adeoye, Berislav V. Zlokovic, E. Clarke Haley, Jon W. Yankey, Robin Conwit, John H. Griffin, Jin-Moo Lee, Natalia S. Rost, Christopher S. Coffey
Publikováno v:
Annals of Neurology. 85:125-136
Objective Agonism of protease-activated receptor (PAR) 1 by activated protein C (APC) provides neuro- and vasculoprotection in experimental neuroinjury models. The pleiotropic PAR1 agonist, 3K3A-APC, reduces neurological injury and promotes vascular
Autor:
Bruce C.V. Campbell, Richard Buchsbaum, Xuya Huang, Bruce Levin, Mark W Parsons, Rachael L. MacIsaac, Christopher R Levi, Christopher F. Bladin, John L.P. Thompson, E. Clarke Haley, Keith W. Muir
Publikováno v:
International Journal of Stroke. 11:534-543
Background Tenecteplase, a modified plasminogen activator with higher fibrin specificity and longer half-life, may have advantages over alteplase in acute ischemic stroke thrombolysis. Aims We undertook an individual patient data meta-analysis of ran
Autor:
Jean Baptiste Le Pichon, Stephanie Lowenhaupt, Jessica Lamb, Eric D. Foster, Patricia K. Coyle, Mariam Andersen, Christine Annis, Alexander J. Stein, Angela Molloy, Tracy A. Glauser, Laurie Gutmann, Steven M. Greenberg, Mengesha Teshome, A. Gordon Smith, Richard J. Barohn, Paula R. Clemens, Susan T. Iannaccone, Robert G. Holloway, Carole Seeley, Luis J. Mejico, Audrey Ellis, Bjorn Oskarsson, Jeremy M. Shefner, Emine O. Bayman, R. Peters, Anthony A. Amato, Louis B. Nabors, Beth A. Malow, Blagovest Nikolov, Mark Quigg, Claudia A. Chiriboga, Peggy Clark, Christine L. Amity, Mark P. Goldberg, Joseph F. Quinn, Trevis Huff, E. Clarke Haley, Codrin Lungu, Kellie Keith, David B. Clifford, Julie Steele, Stephen J. Kolb, Michael Benatar, Muhammad Maaz Iqbal, Shlomo Shinnar, Lawrence R. Wechsler, Basil T. Darras, Melanie Benge, Robin Conwit, Tanya Simuni, Catherine P. Canamar, Timothy Vollmer, Roger J. Packer, Michael Bosch, Khurram Bashir, Sara DeGregorio, Karen W. Adkins, James Bowen, Tina Ward, Dixie Ecklund, Marianne Chase, Bruce H. Dobkin, Stewart A. Factor, Gil I. Wolfe, Katy Mahoney, James C. Torner, Donna Patch, Mariana Doudova, Amy Bartlett, Nadege Gilles, Jeffrey D. Long, Caryl Tongco, Karen Marder, Claire Henchcliffe, Joyce Ann Moran, Mazen M. Dimachkie, Jon W. Yankey, Merit Cudkowicz, J. Robinson Singleton, Craig M. McDonald, Christopher S. Coffey, Annemarie Crumlish, Noreen L. Connolly, Brenda Thornell, John T. Kissel, Steven R. Levine, Kevin J. Staley, Erik K Henricson, Daniel Woo
Publikováno v:
JAMA Neurol
Importance One major advantage of developing large, federally funded networks for clinical research in neurology is the ability to have a trial-ready network that can efficiently conduct scientifically rigorous projects to improve the health of peopl
Autor:
E. Clarke Haley
Publikováno v:
Stroke. 48(8)
> “I get by with a little help from my friends.” > > — The Beatles, 19671 The past 30 years have seen remarkable advances in all areas of medicine, but perhaps none more so than stroke. On the 10th anniversary of the passing of Dr David Sherman
Autor:
Mikael Mazighi, Joseph P. Broderick, Pooja Khatri, Yuko Y. Palesch, Andrew M. Demchuk, Mayank Goyal, Michael D. Hill, Pierre Amarenco, Lydia D. Foster, Sharon D. Yeatts, Achala Vagal, Edward C. Jauch, E. Clarke Haley, Janice Carrozzella, Judith Spilker, Thomas A. Tomsick, David S Liebeskind
Publikováno v:
The Lancet Neurology. 13:567-574
Summary Background The IMS III trial did not show a clinical benefit of endovascular treatment compared with intravenous alteplase (recombinant tissue plasminogen activator) alone for moderate or severe ischaemic strokes. Late reperfusion of tissue t
Selecting Patients for Intra-Arterial Therapy in the Context of a Clinical Trial for Neuroprotection
Autor:
Steven C. Levine, Patrick D. Lyden, Marc Fisher, Lawrence R. Wechsler, Ashutosh P Jadhav, Kent E. Pryor, Sarah O'Brien, Samantha Berg, Pooja Khatri, Howard P. Levy, Sara Weymer, Elizabeth McNeil, E. Clarke Haley, Salina P. Waddy, Jeffrey L. Saver, Merit Cudkowicz, Christopher S. Coffey, Marilyn M. Rymer
Publikováno v:
Stroke, vol 47, iss 12
Background and Purpose— The advent of intra-arterial neurothrombectomy (IAT) for acute ischemic stroke opens a potentially transformative opportunity to improve neuroprotection studies. Combining a putative neuroprotectant with recanalization could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008dab0ed73525450dff28afe8afb46e
https://escholarship.org/uc/item/404458mj
https://escholarship.org/uc/item/404458mj
Autor:
John L.P. Thompson, Bibhas Chakraborty, Robert B. MacArthur, E. Clarke Haley, Gilberto Levy, Bruce Levin
Publikováno v:
Clinical Trials (London, England)
Background TNK-S2B, an innovative, randomized, seamless phase II/III trial of tenecteplase versus rt-PA for acute ischemic stroke, terminated for slow enrollment before regulatory approval of use of phase II patients in phase III. Purpose (1) To revi
Autor:
Richard Buchsbaum, Patrick D. Lyden, Richard B. Libman, John L.P. Thompson, Devin L. Brown, Gilberto Levy, Thomas Kwiatkowski, Thomas G. Hemmen, James C. Grotta, E. Clarke Haley, Rafael H. Llinas, Karen C. Johnston, Bruce Levin, Christopher Fanale, Steven R. Levine
Publikováno v:
Stroke. 41:707-711
Background and Purpose— Intravenous alteplase (rtPA) remains the only approved treatment for acute ischemic stroke, but its use remains limited. In a previous pilot dose-escalation study, intravenous tenecteplase showed promise as a potentially saf
Publikováno v:
Thrombolytic Therapy for Acute Stroke ISBN: 9783319075747
Thrombolytic Therapy for Acute Stroke ISBN: 9781588293985
Thrombolytic Therapy for Acute Stroke ISBN: 9781588293985
Thrombolytic therapy was proposed soon after the discovery of thrombolytic agents, because the majority of acute ischemic strokes result from atherothrombosis or thromboembolism of a cerebral or precerebral artery. Since critical event must be the fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62058e89616fe48fd473d96dc06788fc
https://doi.org/10.1007/978-3-319-07575-4_4
https://doi.org/10.1007/978-3-319-07575-4_4