Zobrazeno 1 - 10
of 268
pro vyhledávání: '"E. Campillo"'
Publikováno v:
Physical Review Research, Vol 6, Iss 3, p 033218 (2024)
2H-NbS_{2} is a classic example of an anisotropic multiband superconductor, with significant recent work focusing on the interesting responses seen when high magnetic fields are applied precisely parallel to the hexagonal niobium planes. It is often
Externí odkaz:
https://doaj.org/article/3b02e5c248aa432ba84e10fb56aa271f
Autor:
L. Shen, E. Campillo, O. Zaharko, P. Steffens, M. Boehm, K. Beauvois, B. Ouladdiaf, Z. He, D. Prabhakaran, A. T. Boothroyd, E. Blackburn
Publikováno v:
Physical Review Research, Vol 4, Iss 1, p 013111 (2022)
We present a systematic inelastic neutron scattering and neutron diffraction study on the magnetic structure of the quasi-one-dimensional spin-1/2 magnet SrCo_{2}V_{2}O_{8}, where the interchain coupling in the Néel-type antiferromagnetic ground sta
Externí odkaz:
https://doaj.org/article/b91e54ae9f3b47f09b7e65c788539aac
Autor:
Pedro González-Naranjo, Concepción Pérez, Marina González-Sánchez, Adrián Gironda-Martínez, Eugenia Ulzurrun, Fernando Bartolomé, Marcos Rubio-Fernández, Angeles Martin-Requero, Nuria E. Campillo, Juan A. Páez
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2348-2356 (2022)
Multitarget drugs are a promising therapeutic approach against Alzheimer’s disease. In this work, a new family of 5-substituted indazole derivatives with a multitarget profile including cholinesterase and BACE1 inhibition is described. Thus, the sy
Externí odkaz:
https://doaj.org/article/4413ef31a44a48d79464776ae07d0209
Autor:
María Jimena Martínez, Roi Naveiro, Axel J. Soto, Pablo Talavante, Shin-Ho Kim Lee, Ramón Gómez Arrayas, Mario Franco, Pablo Mauleón, Héctor Lozano Ordóñez, Guillermo Revilla López, Marco Bernabei, Nuria E. Campillo, Ignacio Ponzoni
Publikováno v:
Polymers, Vol 15, Iss 5, p 1324 (2023)
Artificial intelligence (AI) is an emerging technology that is revolutionizing the discovery of new materials. One key application of AI is virtual screening of chemical libraries, which enables the accelerated discovery of materials with desired pro
Externí odkaz:
https://doaj.org/article/f437d7b0a41c4524bff817acb649ed59
Autor:
Paula Martínez de Iturrate, Victor Sebastián-Pérez, Montserrat Nácher-Vázquez, Catherine S. Tremper, Despina Smirlis, Julio Martín, Ana Martínez, Nuria E. Campillo, Luis Rivas, Carmen Gil
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 199-210 (2020)
Previous reports have validated the glycogen synthase kinase-3 (GSK-3) as a druggable target against the human protozoan parasite Leishmania. This prompted us to search for new leishmanicidal scaffolds as inhibitors of this enzyme from our in-house l
Externí odkaz:
https://doaj.org/article/3b09ef3f651f4ec6a08ecd783dbfddba
Autor:
Victor Sebastian-Perez, Alfonso García-Rubia, Sayed H. Seif el-Din, Abdel-Nasser A. Sabra, Naglaa M. El-Lakkany, Samia William, Tom L. Blundell, Louis Maes, Ana Martinez, Nuria E. Campillo, Sanaa S. Botros, Carmen Gil
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 511-523 (2020)
A previous phenotypic screening campaign led to the identification of a quinazoline derivative with promising in vitro activity against Schistosoma mansoni. Follow-up studies of the antischistosomal potential of this candidate are presented here. The
Externí odkaz:
https://doaj.org/article/10ae8ac3a4a045c9a8ac608b77a542f3
Autor:
M. Lourdes Sciú, Victor Sebastián-Pérez, Loreto Martinez-Gonzalez, Rocio Benitez, Daniel I. Perez, Concepción Pérez, Nuria E. Campillo, Ana Martinez, E. Laura Moyano
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 87-96 (2019)
Numerous studies have highlighted the implications of the glycogen synthase kinase 3 (GSK-3) in several processes associated with Alzheimer’s disease (AD). Therefore, GSK-3 has become a crucial therapeutic target for the treatment of this neurodege
Externí odkaz:
https://doaj.org/article/02eaf3ea1ac54fe49215488f90ef2ccd
Autor:
Victor Sebastián-Pérez, Paula Martínez de Iturrate, Montserrat Nácher-Vázquez, Luis Nóvoa, Concepción Pérez, Nuria E. Campillo, Carmen Gil, Luis Rivas
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1136 (2022)
More than 1 billion people live in areas endemic for leishmaniasis, which is a relevant threat for public health worldwide. Due to the inadequate treatments, there is an urgent need to develop novel alternative drugs and to validate new targets to fi
Externí odkaz:
https://doaj.org/article/ce30c60ca1094e89aab2b03ea997b1f8
Autor:
Gildardo Rivera, Alfredo Juárez-Saldivar, Nuria E. Campillo, Eyra Ortiz-Perez, Alma D. Paz-Gonzalez, Emma Saavedra
Publikováno v:
Medicinal Chemistry. 19:91-98
Background: Currently, protozoan infectious diseases affect billions of people every year. Their pharmacological treatments offer few alternatives and are restrictive due to undesirable side effects and parasite drug resistance. Objective: In this wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ee876878816d57ea719c7afa3532d5
https://doi.org/10.2174/1573406418666220816121912
https://doi.org/10.2174/1573406418666220816121912
Autor:
Carlos Roca, Carlos Requena, Víctor Sebastián-Pérez, Sony Malhotra, Chris Radoux, Concepción Pérez, Ana Martinez, Juan Antonio Páez, Tom L. Blundell, Nuria E. Campillo
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1034-1047 (2018)
Allosteric sites on proteins are targeted for designing more selective inhibitors of enzyme activity and to discover new functions. Acetylcholinesterase (AChE), which is most widely known for the hydrolysis of the neurotransmitter acetylcholine, has
Externí odkaz:
https://doaj.org/article/031329b95fd744a790fa10f49f5f386c