Zobrazeno 1 - 10
of 24
pro vyhledávání: '"E. CHURCHILL MCKINNEY"'
Publikováno v:
The Journal of Immunology. 184:6950-6960
Cartilaginous fish are the oldest animals that generate RAG-based Ag receptor diversity. We have analyzed the genes and expressed transcripts of the four TCR chains for the first time in a cartilaginous fish, the nurse shark (Ginglymostoma cirratum).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a3333cf6bc09e499d53f72478eb486
https://doi.org/10.4049/jimmunol.0902774
https://doi.org/10.4049/jimmunol.0902774
Publikováno v:
Developmental & Comparative Immunology. 28:781-792
T cell receptor (TCR) chains are composed of two extracellular domains, the membrane-distal variable domain and the membrane-proximal constant domain. Data presented here show that the TCRA 'constant' (C) domain of damselfish exhibits considerable al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01591d5303281a3a428ead713d657e4
https://doi.org/10.1016/j.dci.2003.12.004
https://doi.org/10.1016/j.dci.2003.12.004
Publikováno v:
Immunogenetics. 55:818-824
T-cell receptor chains contain membrane-proximal constant domains of the immunoglobulin superfamily that are relatively invariant in mammalian species. In contrast, recent studies in the bicolor damselfish have demonstrated surprising allelic polymor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cb55140d93efa31376a18967cf2ec3
https://doi.org/10.1007/s00251-004-0652-7
https://doi.org/10.1007/s00251-004-0652-7
Publikováno v:
The Journal of Immunology. 168:771-781
Cartilaginous fish (e.g., sharks) are derived from the oldest vertebrate ancestor having an adaptive immune system, and thus are key models for examining MHC evolution. Previously, family studies in two shark species showed that classical class I (UA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fff2eadd4bfb15a6890404f4f7681d
https://doi.org/10.4049/jimmunol.168.2.771
https://doi.org/10.4049/jimmunol.168.2.771
Autor:
E. Churchill McKinney, Yuko Ohta, Keiichiro Hashimoto, Kazuhiko Okamura, Simona Bartl, Martin F. Flajnik
Publikováno v:
Proceedings of the National Academy of Sciences. 97:4712-4717
Major histocompatibility complex (MHC) class I and class II molecules bind to and display peptidic antigens acquired from pathogens that are recognized by lymphocytes coordinating and executing adaptive immune responses. The two classes of MHC protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f53de0419e9c1cf35e3270ca4fbeac
https://doi.org/10.1073/pnas.97.9.4712
https://doi.org/10.1073/pnas.97.9.4712
Publikováno v:
Developmental & Comparative Immunology. 21:287-298
Lymphocytes from tumor-bearing damselfish are cytotoxic towards target cell lines derived from damselfish neurofibromatosis. These cell lines contain at least one retrovirus which appears to be related to the etiology of the disease. The current stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9f344ca7b7464791f94dbbd12498b1
https://doi.org/10.1016/s0145-305x(97)00010-4
https://doi.org/10.1016/s0145-305x(97)00010-4
Autor:
E. Churchill McKinney
Publikováno v:
Annual Review of Fish Diseases. 2:43-51
Shark lymphocytes have been characterized by the presence or absence of surface immunoglobulin (SIg). Thus, SIg + cells are B lymphocytes, and SIg − cells are presumed to include the shark T cell subset, as well as other minor subsets of lymphocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ba9a1ed8165c65371df59c029729a00
https://doi.org/10.1016/0959-8030(92)90055-3
https://doi.org/10.1016/0959-8030(92)90055-3
Autor:
E. Churchill McKinney, Laura Haynes
Publikováno v:
Developmental & Comparative Immunology. 15:123-134
Down regulation of shark macrophage-mediated spontaneous cytotoxicity is evident in vitro when animals are maintained at environmental temperatures greater than 26°C. Previous work has shown that inhibition of spontaneous killing is mediated by viab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09a5a240c4b5f769caa09592be7a1a4
https://doi.org/10.1016/0145-305x(91)90003-h
https://doi.org/10.1016/0145-305x(91)90003-h
Publikováno v:
Molecular Evolution of the Major Histocompatibility Complex ISBN: 9783642846243
In the course of our study aimed at isolating class II genes of the major histocompatibility complex from primitive vertebrates, nurse shark cDNA clones assumed to encode a nucleoside diphosphate kinase were isolated. The deduced amino acid sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efb6d7f405859c9f4e9536fe356f0092
https://doi.org/10.1007/978-3-642-84622-9_40
https://doi.org/10.1007/978-3-642-84622-9_40
