Zobrazeno 1 - 10
of 15
pro vyhledávání: '"E. C. J. Coffee"'
Publikováno v:
Synthetic Communications. 23:613-620
Convenient syntheses of the epimeric 3-hydroxy-2α-carb-oxybicyclo[3.3.0]octane-4α,6α-carbolactones are described which commence from the readily available cyclopentadienone dimer.
Publikováno v:
ChemInform. 24
Convenient syntheses of the epimeric 3-hydroxy-2α-carb-oxybicyclo[3.3.0]octane-4α,6α-carbolactones are described which commence from the readily available cyclopentadienone dimer.
Autor:
E. C. J. Coffee, Bridge Andrew William, Neil Victor Harris, Christopher Smith, Dron Donald Ian, Ashton Michael John, Christopher G. Newton, David J. Lythgoe, M. F. Harper, R.C. Bush, David Riddell
Publikováno v:
ChemInform. 24
Autor:
Neil Victor Harris, M. F. Harper, Bridge Andrew William, E. C. J. Coffee, Ashton Michael John, R.C. Bush, Christopher Smith, Dron Donald Ian, Christopher G. Newton, David J. Lythgoe
Publikováno v:
Journal of Medicinal Chemistry. 35:4384-4392
A potent, bioavailable ACAT inhibitor may have beneficial effects in the treatment of atherosclerosis by (i) reducing the absorption of dietary cholesterol, (ii) reducing the secretion of very low density lipoproteins into plasma from the liver, and
Publikováno v:
ChemInform. 21
Convenient syntheses of some bifunctionally substituted [3.3.1] propellanes are reported from the readily accessible tricyclo[4.3.11,6] dec-3-en-8-ol.
Autor:
A. H. Loveless, J. R. Clark, K. R. H. Wooldridge, E. C. J. Coffee, Berkeley Basil, D. L. Pain, R. Jordan
Publikováno v:
Journal of Medicinal Chemistry. 19:399-402
A series of 1-(2-acyl-4-acylaminophenoxy)-3-isopropylaminopropan-2-ols has been synthesized and examined for beta-receptor blocking and antiarrhythmic activity. Several of these compounds are more than 20 times as active in blocking cardiac beta-rece
Publikováno v:
Synthetic Communications. 19:1225-1232
Convenient syntheses of some bifunctionally substituted [3.3.1] propellanes are reported from the readily accessible tricyclo[4.3.11,6] dec-3-en-8-ol.
Autor:
C. W. BIRD, H. I. BUTLER, M. P. L. CATON, E. C. J. COFFEE, C. J. HARDY, T. W. HART, H. J. MASON
Publikováno v:
Chemischer Informationsdienst. 17
Publikováno v:
ChemInform. 19
The cis-decalindione (I), obtained from naphthalene-2,7-diol by hydrogenation and oxidation, is oxidized to give the oxabicyclo(4.3.0)nonanecarboxylic acid (II), which is converted into the homocarbaprostacyclin (X) as shown in the reaction scheme.
Autor:
R. Jordan, A. H. Loveless, D. L. Pain, J. R. Clark, E. C. J. Coffee, Berkeley Basil, K. R. H. Wooldridge
Publikováno v:
Chemischer Informationsdienst. 7