Zobrazeno 1 - 10
of 50
pro vyhledávání: '"E. Burgert"'
Autor:
William C Reisdorf, Qing Xie, Xin Zeng, Wensheng Xie, Neetu Rajpal, Bao Hoang, Mark E Burgert, Vinod Kumar, Mark R Hurle, Deepak K Rajpal, Sarah O'Donnell, Thomas T MacDonald, Anna Vossenkämper, Lin Wang, Mike Reilly, Bart J Votta, Yolanda Sanchez, Pankaj Agarwal
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215033 (2019)
Epoxyeicosatrienoic acids (EETs) are signaling lipids produced by cytochrome P450 epoxygenation of arachidonic acid, which are metabolized by EPHX2 (epoxide hydrolase 2, alias soluble epoxide hydrolase or sEH). EETs have pleiotropic effects, includin
Externí odkaz:
https://doaj.org/article/38fb9ef315534f3a84f10666efe0bd55
Effect of topical soluble epoxide hydrolase inhibition in a preclinical diabetic wound healing model
Autor:
Mark E. Burgert, Rajpal N, William C. Reisdorf, Deepak K. Rajpal, Gehman Aj, Sonti S, Pankaj K. Agarwal, Jain P
The objective of this study was to test a topical formulation of EPHX2 inhibitor, GSK2256294, in a dermal wound diabetic (db/db) mouse model. Comparisons were made between groups treated with EPHX2 inhibitor, matching vehicle control and a currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cea8d8ae673d87340830cf9a5bcb5b
https://doi.org/10.1101/571984
https://doi.org/10.1101/571984
Autor:
Vinod Kumar, Qing Xie, Anna Vossenkämper, Bao Hoang, Mark E. Burgert, Mike Reilly, Lin Wang, Wensheng Xie, Mark R. Hurle, Bart Votta, Neetu Rajpal, Pankaj K. Agarwal, Xin Zeng, Thomas T. MacDonald, Deepak K. Rajpal, Sarah O’Donnell, William C. Reisdorf, Yolanda Sanchez
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215033 (2019)
Epoxyeicosatrienoic acids (EETs) are signaling lipids produced by cytochrome P450 epoxygenation of arachidonic acid, which are metabolized by EPHX2 (epoxide hydrolase 2, alias soluble epoxide hydrolase or sEH). EETs have pleiotropic effects, includin
Autor:
Andrea J Evenski, Nicole D. Riddle, John S.J. Brooks, Richard D. Lackman, Christine E Burgert-Lon
Publikováno v:
American Journal of Surgical Pathology. 39:1540-1547
Little is known about the etiology or pathogenesis of angiosarcoma (AS). We describe a series of 5 cases of AS arising in chronic expanding hematomas. Inclusion criteria were the presence of a hematoma of at least 1-year duration and a thick fibrous
Autor:
Ping Zhang, Yi Shi, Damir Hamamdzic, Christine L. Webb, Daniel J Pelchovitz, M Walker, Jun Li, Mark E. Burgert, LeFeng Zhang, Jisheng Yang, Anthony D. Postle, Rosanna C. Mirabile, Emile R. Mohler, Bryan E. Hoffman, Andrew Zalewski, Robert S. Fenning, Robert L. Wilensky, James G. Bollinger, Michael H. Gelb, Colin H. Macphee
Publikováno v:
Nature Medicine. 14:1059-1066
Increased lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) activity is associated with increased risk of cardiac events, but it is not known whether Lp-PLA(2) is a causative agent. Here we show that selective inhibition of Lp-PLA(2) with darapla
Autor:
Beat M. Jucker, Robert L. Wilensky, Eliot G Peyster, Robert S. Fenning, Mark E. Burgert, Stephen C. Lenhard, Emile R. Mohler, Colin H. Macphee, Damir Hamamdzic, Shreya Kangovi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Despite systemic exposure to risk factors, the circulatory system develops varying patterns of atherosclerosis for unclear reasons. In a porcine model, we investigated the relationship between site‐specific lesion development and inflamm
Autor:
Gunnar Rylander, E. Burgert, J. Petter Gustavsson, Marc-Antoine Crocq, Frits-Axel Wiesel, Hans Bergman, Erik G. Jönsson, Lars Bjerkenstedt, Marie Åsberg, Kaj Forslund, Lena Flyckt, Marja Mattila-Evenden
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :61-65
Dopamine receptor gene variation has been hypothesized to influence personality traits characterized by novelty seeking and related traits. We analyzed a dopamine D3 receptor gene (DRD3) variant in a Swedish population (n = 373) investigated with one
Autor:
S.H. Shaw, Erik G. Jönsson, E. Burgert, Göran Sedvall, X. R. Zhang, Aravinda Chakravarti, Vishwajit L. Nimgaonkar, Marc-Antoine Crocq
Publikováno v:
American Journal of Medical Genetics. 88:352-357
There is considerable controversy regarding a putative association between schizophrenia and a biallelic BalI polymorphism in the first exon of the dopamine D3 receptor gene (DRD3), although meta-analyses of published data suggest an association. If
Publikováno v:
Psychiatric Genetics. 8:45-48
Linkage and association studies have implicated the involvement of the tyrosine hydroxylase (TH) gene on chromosome 11p15 in schizophrenia and bipolar disorder (BPD). An association of BPD with a polymorphic tetranucleotide repeat, HUMTH01, located i
Autor:
Fabrice Duval, Deborah J. Morris-Rosendahl, Jean-Paul Macher, Marc-Antoine Crocq, Antonia Mayerová, Gökhan Uyanik, E. Burgert
Publikováno v:
American Journal of Medical Genetics. 74:324-330
We have genotyped unrelated French Alsatian schizophrenic and bipolar I disorder (BPD) patients and matched controls for the polymorphic CAG repeats within the genes for spinocerebellar ataxia type 1 (SCA1) and dentatorubral-pallidoluysian atrophy (B