Zobrazeno 1 - 10
of 65
pro vyhledávání: '"E. Bryan Crenshaw"'
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226602 (2019)
Bone morphogenetic proteins (BMPs) have been hypothesized to specify distinct dorsal neural fates. During neural development, BMPs are expressed in the roof plate and adjacent neuroepithelium. Because several hindbrain nuclei that form the propriocep
Externí odkaz:
https://doaj.org/article/e49e460062344a5284df5d216bb40c19
Publikováno v:
Ear Hear
OBJECTIVES: This study identified an association between cholesteatoma and progressive sensorineural hearing loss using a large pediatric longitudinal audiologic dataset. Cholesteatoma is a potential sequelae of chronic otitis media with effusion, a
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109043 (2014)
The temporal bone encases conductive and sensorineural elements of the ear. Mutations of POU3F4 are associated with unique temporal bone abnormalities and X-linked mixed deafness (DFNX2/DFN3). However, the target genes and developmental processes con
Externí odkaz:
https://doaj.org/article/5db4684cf0444b1b8a12c24aea238b8c
Publikováno v:
ASN Neuro, Vol 3 (2011)
OLs (oligodendrocytes) are the myelinating cells of the CNS (central nervous system), wrapping axons in conductive sheathes to ensure effective transmission of neural signals. The regulation of OL development, from precursor to mature myelinating cel
Externí odkaz:
https://doaj.org/article/8b2fe499a0a64dcd94c776160d7b360a
Autor:
Margaret A. Kenna, Ian D. Krantz, Linda J. Hood, Aaron J. Masino, Byron Ruth, Baichen Xu, Tamar Gomes, Juliana Manganella, E. Bryan Crenshaw, Derek J. Stiles, John A. Germiller, Joy Peterson, Jeffrey W. Pennington, Jeffrey M. Miller
Publikováno v:
Ear Hear
The use of "big data" for pediatric hearing research requires new approaches to both data collection and research methods. The widespread deployment of electronic health record systems creates new opportunities and corresponding challenges in the sec
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0226602 (2019)
PLoS ONE, Vol 14, Iss 12, p e0226602 (2019)
Bone morphogenetic proteins (BMPs) have been hypothesized to specify distinct dorsal neural fates. During neural development, BMPs are expressed in the roof plate and adjacent neuroepithelium. Because several hindbrain nuclei that form the propriocep
Autor:
Stacey Wrazien, Jeffrey M. Miller, Jennifer G. Loutrel, Peter White, Michael J. Italia, E. Bryan Crenshaw, Byron Ruth, Jeffrey W. Pennington
Publikováno v:
Journal of the American Medical Informatics Association : JAMIA
Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems
Autor:
Ian D. Krantz, E. Bryan Crenshaw, Devanshi Mehta, Emily Schwartz, Irene Scarano, Emma Bedoukian, Sarah E. Noon, Alisha Wilkens
Publikováno v:
American journal of medical genetics. Part A. 170(10)
Hearing loss is a relatively common condition in children, occurring in approximately 2 out of every 1,000 births with approximately 50% of reported diagnoses having a primary genetic etiology. Given the prevalence and genetic component of hearing lo
Autor:
Xiumei Zhao, Aimee K. Ryan, Matthew W. Kelley, Thomas M. Coate, E. Bryan Crenshaw, Steven Raft
Publikováno v:
Neuron. 73:49-63
Summary Peripheral axons from auditory spiral ganglion neurons (SGNs) form an elaborate series of radially and spirally oriented projections that interpret complex aspects of the auditory environment. However, the developmental processes that shape t
Autor:
Michael Wegner, Daniela C. Thein, E. Bryan Crenshaw, Johannes M. Thalhammer, Elisabeth Sock, Véronique Lefebvre, Anna C. Hartwig
Publikováno v:
Journal of Neurochemistry. 115:131-141
Development of the mouse CNS was reported to be normal in the absence of either Sox4 or its close relative Sox11 despite strong and widespread expression of both transcription factors. In this study, we show that combined absence of both Sox proteins