Zobrazeno 1 - 10
of 625
pro vyhledávání: '"E. Birk"'
Autor:
Mengjie Zhu, Fabian Metzen, Mark Hopkinson, Janina Betz, Juliane Heilig, Jassi Sodhi, Thomas Imhof, Anja Niehoff, David E. Birk, Yayoi Izu, Marcus Krüger, Andrew A. Pitsillides, Janine Altmüller, Gerjo J.V.M. van Osch, Volker Straub, Gudrun Schreiber, Mats Paulsson, Manuel Koch, Bent Brachvogel
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107225- (2023)
Summary: Collagen XII, belonging to the fibril-associated collagens, is a homotrimeric secreted extracellular matrix (ECM) protein encoded by the COL12A1 gene. Mutations in the human COL12A1 gene cause an Ehlers-Danlos/myopathy overlap syndrome leadi
Externí odkaz:
https://doaj.org/article/9b9be6f40bdd4d2e8ab523d6005f0342
Autor:
Yayoi Izu, David E. Birk
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Collagen XII, a fibril-associated collagen with interrupted triple helices (FACIT), influences fibrillogenesis in numerous tissues. In addition to this extracellular function, collagen XII also directly regulates cellular function. Collagen XII is wi
Externí odkaz:
https://doaj.org/article/192d0e699eb94385b5403d8a0281cfd1
Autor:
Chang Yeop Han, Inkyung Kang, Ingrid A. Harten, John A. Gebe, Christina K. Chan, Mohamed Omer, Kimberly M. Alonge, Laura J. den Hartigh, Diego Gomes Kjerulf, Leela Goodspeed, Savitha Subramanian, Shari Wang, Francis Kim, David E. Birk, Thomas N. Wight, Alan Chait
Publikováno v:
Cell Reports, Vol 31, Iss 13, Pp 107818- (2020)
Summary: Obesity is characterized by adipose tissue inflammation. Because proteoglycans regulate inflammation, here we investigate their role in adipose tissue inflammation in obesity. We find that adipose tissue versican and biglycan increase in obe
Externí odkaz:
https://doaj.org/article/0ab5266a0eec4194a0bd5b3e2ad576af
Autor:
Sarah E. Birk, David A. Baran, Robert Campbell, John M. Herre, Hessam Sadatsafavi, Amin Yehya
Publikováno v:
The Journal of Heart and Lung Transplantation.
Akademický článek
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Autor:
Zakary M. Beach, Kelsey A. Bonilla, Mihir S. Dekhne, Mei Sun, Thomas H. Adams, Sheila M. Adams, Stephanie N. Weiss, Ashley B. Rodriguez, Snehal S. Shetye, David E. Birk, Louis J. Soslowsky
Publikováno v:
Journal of Orthopaedic Research. 40:2546-2556
Decorin and biglycan are two small leucine-rich proteoglycans (SLRPs) that regulate collagen fibrillogenesis and extracellular matrix assembly in tendon. The objective of this study was to determine the individual roles of these molecules in maintain
Publikováno v:
European Archives of Oto-Rhino-Laryngology.
Autor:
Tanya Papaz, HBA, Upton Allen, MBBS, Tom Blydt-Hansen, MD, Patricia E. Birk, MD, Sandar Min, MBBS, Lorraine Hamiwka, MD, Veronique Phan, MD, Tal Schechter, MD, Donna A. Wall, MD, Simon Urschel, MD, Bethany J. Foster, MD, Seema Mital, MD
Publikováno v:
Transplantation Direct, Vol 4, Iss 12, p e410 (2018)
Background. Despite age-related differences in biology, physiology, and behavior, transplant immunosuppression is not tailored by age. This likely contributes to high graft failure and posttransplant complications. We present the aims, design, and me
Externí odkaz:
https://doaj.org/article/f65ea14b6bad46348c3f6a125b1a988c
Publikováno v:
Matrix biology plus. 16
Collagen XII is a fibril-associated collagen with interrupted triple helices (FACIT). This non-fibrillar collagen is a homotrimer composed of three α1(XII) chains assembled into a collagenous molecule with a C terminal collagenous domain and a large
Autor:
A. Nicole Lambert, Tom Blydt-Hansen, Noureddine Berka, Patricia Campbell, Sandar Min, Hartmut Grasemann, Simon Urschel, Kathryn Tinckham, Chee Loong Saw, Upton Allen, Tanya Papaz, Bethany J. Foster, Patricia E. Birk, Vicky L. Ng, Seema Mital, Sara L. Van Driest, Catherine Litalien, Rulan S. Parekh, Lorraine A. Hamiwka, Daniel Claude
Publikováno v:
Transplantation. 106:597-606
BACKGROUND There are challenges in achieving and maintaining therapeutic tacrolimus levels after solid organ transplantation (SOT). The purpose of this genome-wide association study (GWAS) was to generate an integrated clinical and genetic prediction