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Akademický článek

Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype

Autor: I. Plastira, E. Bernhart, M. Goeritzer, T. DeVaney, H. Reicher, A. Hammer, B. Lohberger, A. Wintersperger, B. Zucol, W. F. Graier, D. Kratky, E. Malle, W. Sattler

Publikováno v: Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-28 (2017)

Abstract Background Extracellular lysophosphatidic acid (LPA) species transmit signals via six different G protein-coupled receptors (LPAR1–6) and are indispensible for brain development and function of the nervous system. However, under neuroinfla

Externí odkaz: https://doaj.org/article/275bdff4de584594a8741445fdbfe635

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Akademický článek

Experimental observation of a dissipative phase transition in a multi-mode many-body quantum system

Autor: J Benary, C Baals, E Bernhart, J Jiang, M Röhrle, H Ott

Publikováno v: New Journal of Physics, Vol 24, Iss 10, p 103034 (2022)

Dissipative phase transitions are a characteristic feature of open systems. One of the paradigmatic examples for a first order dissipative phase transition is the driven nonlinear single-mode optical resonator. In this work, we study a realization wi

Externí odkaz: https://doaj.org/article/f42de76ec53841d28092700dfae64fa1

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Akademický článek

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A new path: student pioneers and communication practices in rural Mexico

Autor: Susan E. Bernhart

Publikováno v: The Journal of International Communication. 26:59-72

The study examines the beliefs and attitudes that shape the communication among university students in Cerritos, San Luis Potosi. The Mexican national movement to increase access to higher educatio...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fff062fb6bdee17b0704b02e354db3b9
https://doi.org/10.1080/13216597.2020.1728360

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Akademický článek

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Akademický článek

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Additional file 4: Figure S4. of Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype

Autor: I. Plastira, E. Bernhart, M. Goeritzer, T. DeVaney, H. Reicher, A. Hammer, B. Lohberger, A. Wintersperger, B. Zucol, W. Graier, D. Kratky, E. Malle, W. Sattler

TCLPA5 inhibits the phosphorylation of pro-inflammatory transcription factors. BV-2 microglia cells were cultured in 6-well plates and serum-starved overnight. Cells were treated with LPA (1 μM) or LPA (1 μM) in the presence of (A) TCLPA5 (5 μM) f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::038c41818bc9280da15f894364d5e682

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Additional file 6: Figure S6. of Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype

Autor: I. Plastira, E. Bernhart, M. Goeritzer, T. DeVaney, H. Reicher, A. Hammer, B. Lohberger, A. Wintersperger, B. Zucol, W. Graier, D. Kratky, E. Malle, W. Sattler

PKD family members control the secretion of pro-inflammatory cytokines and chemokines. BV-2 cells were cultured on 12-well plates; serum-starved o/n and the supernatants were collected after incubation with DMSO, DMSO plus LPA (1 μM) or LPA (1 μM)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eccd9574d82dfc20c4f584c668e149c2

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Additional file 3: Figure S3. of Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype

Autor: I. Plastira, E. Bernhart, M. Goeritzer, T. DeVaney, H. Reicher, A. Hammer, B. Lohberger, A. Wintersperger, B. Zucol, W. Graier, D. Kratky, E. Malle, W. Sattler

LPA promotes activation of pro-inflammatory transcription factors in BV-2 cells. Serum-starved (A) BV-2 cells were treated with 0.1% BSA (control) or LPA (1 μM) for the indicated time periods, the cellular protein lysates were collected and phosphor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b8b625a41bb2501c037d35893fad550

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Additional file 5: Figure S5. of Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype

Autor: I. Plastira, E. Bernhart, M. Goeritzer, T. DeVaney, H. Reicher, A. Hammer, B. Lohberger, A. Wintersperger, B. Zucol, W. Graier, D. Kratky, E. Malle, W. Sattler

The phosphorylation of pro-inflammatory transcription factors is under PKD family control. BV-2 cells, serum-starved overnight and treated with LPA (1 μM) or LPA (1 μM) in the presence of (A) CRT0066101 (1 μM) for the indicated time periods. Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c2002f48134aa1aa2f2890b533f58fe

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