Zobrazeno 1 - 10
of 11
pro vyhledávání: '"E. Benjamin Randall"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: The left (LV) and right (RV) ventricles are linked biologically, hemodynamically, and mechanically, a phenomenon known as ventricular interdependence. While LV function has long been known to impact RV function, the reverse is increasin
Externí odkaz:
https://doaj.org/article/79a7d4ab51be46bd91bb0decbc5d8d94
Autor:
Feng Gu, E. Benjamin Randall, Steven Whitesall, Kimber Converso-Baran, Brian E. Carlson, Gregory D. Fink, Daniel E. Michele, Daniel A. Beard
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
The spontaneously hypertensive rat (SHR) is a genetic model of primary hypertension with an etiology that includes sympathetic overdrive. To elucidate the neurogenic mechanisms underlying the pathophysiology of this model, we analyzed the dynamic bar
Externí odkaz:
https://doaj.org/article/673ba72f27fc41bc8d642cb0753088f3
Autor:
Brian E. Carlson, Edith Jones, Daniel A. Beard, Scott L. Hummel, E. Benjamin Randall, David M. Cameron
Publikováno v:
J Physiol
To phenotype mechanistic differences between heart failure with reduced (HFrEF) and preserved (HFpEF) ejection fraction, a closed-loop model of the cardiovascular system coupled with patient-specific transthoracic echocardiography (TTE) and right hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f3378554557d2280e8a64338200116
https://europepmc.org/articles/PMC8595692/
https://europepmc.org/articles/PMC8595692/
Autor:
Daniel A. Beard, Bahador Marzban, Rachel Lopez, Marcus Hock, Collin Marshall, E. Benjamin Randall
Publikováno v:
Math Biosci
We present a computational framework for analyzing and simulating mitochondrial ATP synthesis using basic thermodynamic and kinetic principles. The framework invokes detailed descriptions of the thermodynamic driving forces associated with the proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99c1496a685c65eb33b23b6c6036e66
https://europepmc.org/articles/PMC8434986/
https://europepmc.org/articles/PMC8434986/
Publikováno v:
Journal of molecular and cellular cardiology. 163
Blood flows and pressures throughout the human cardiovascular system are regulated in response to various dynamic perturbations, such as changes to peripheral demands in exercise, rapid changes in posture, or loss of blood from hemorrhage, via the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7dc68e169b8f95f81396f318134f1a
https://pubmed.ncbi.nlm.nih.gov/34626617
https://pubmed.ncbi.nlm.nih.gov/34626617
Autor:
Brian E. Carlson, Steven E. Whitesall, Feng Gu, Daniel E. Michele, E. Benjamin Randall, Daniel A. Beard, Gregory D. Fink, Kimber Converso-Baran
Publikováno v:
JCI Insight
JCI Insight, Vol 5, Iss 19 (2020)
JCI Insight, Vol 5, Iss 19 (2020)
The spontaneously hypertensive rat (SHR) is a genetic model of primary hypertension with an etiology that includes sympathetic overdrive. To elucidate the neurogenic mechanisms underlying the pathophysiology of this model, we analyzed the dynamic bar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769c6e33b7c607e36c87862c9f43a242
https://pubmed.ncbi.nlm.nih.gov/33004690
https://pubmed.ncbi.nlm.nih.gov/33004690
Publikováno v:
J Theor Biol
In this study, we develop a methodology for model reduction and selection informed by global sensitivity analysis (GSA) methods. We apply these techniques to a control model that takes systolic blood pressure and thoracic tissue pressure data as inpu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4678b52a2b86c1406568d35c791015
Publikováno v:
Biophysical Journal. 121:124a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24e3a4e1a1e5f951a4f51428d0f5d1d4
https://doi.org/10.1016/j.bpj.2021.11.2104
https://doi.org/10.1016/j.bpj.2021.11.2104
Delay differential equations (DDEs) are widely used in mathematical modeling to describe physical and biological systems. Delays can impact model dynamics, resulting in oscillatory behavior. In physiological systems, this instability may signify (i)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0c6f421dcb77f47c015eb96f3a516e
http://arxiv.org/abs/1908.09371
http://arxiv.org/abs/1908.09371
Publikováno v:
J Appl Physiol (1985)
The Valsalva maneuver (VM) is a diagnostic protocol examining sympathetic and parasympathetic activity in patients with autonomic dysfunction (AD) impacting cardiovascular control. Because direct measurement of these signals is costly and invasive, A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd205b3a8cba6f56c3276b5f474ab32f
https://pubmed.ncbi.nlm.nih.gov/31369335
https://pubmed.ncbi.nlm.nih.gov/31369335