Linking Microdosimetric Measurements to Biological Effectiveness in Ion Beam Therapy: A Review of Theoretical Aspects of MKM and Other Models

Autor: V. E. Bellinzona, F. Cordoni, M. Missiaggia, F. Tommasino, E. Scifoni, C. La Tessa, A. Attili

Publikováno v: Frontiers in Physics, Vol 8 (2021)

Different qualities of radiation are known to cause different biological effects at the same absorbed dose. Enhancements of the biological effectiveness are a direct consequence of the energy deposition clustering at the scales of DNA molecule and ce

Externí odkaz: https://doaj.org/article/77df71eebe494cd4a3b540ea18604b73

THE FOOT EXPERIMENT: FRAGMENTATION MEASUREMENTS IN PARTICLE THERAPY

Autor: E. Bellinzona, Nadia Pastrone, Alessandro Pastore, E. López Torres, M. Selvi, L. Alunni Solestizi, Pisana Placidi, E. Iarocci, F. Ferroni, Silvia Muraro, C. La Tessa, M. C. Morone, E. Spiriti, M. Ionica, P. Cerello, Y. Dong, R. Arteche Diaz, A. Zoccoli, A. Secher, Giuliana Galati, V. Lante, Elisa Fiorina, Christoph Schuy, M. De Simoni, M. Vanstalle, Luciano Ramello, K. Kanxheri, Stefano Argiro, S. M. Valle, M. Donetti, M. Garbini, A. C. Kraan, R. Ridolfi, Alberto Mengarelli, Marco Durante, N. Bartosik, A. Moggi, Valeria Rosso, M. Emde, Giacomo Traini, Angelo Schiavi, F. Raffaeli, Niccolò Camarlinghi, M. Pullia, M. Francesconi, G. De Lellis, L. Scavarda, M. Franchini, Mario Sitta, M. Villa, E. Fiandrini, M. Rovituso, Ilaria Mattei, R. Faccini, Alberto Clozza, S. Savazzi, Gabriella Sartorelli, Graziano Bruni, Matteo Morrocchi, Esther Ciarrocchi, Vincenzo Patera, A. Di Crescenzo, A. Sciubba, A. Del Guerra, G. Ambrosi, Valeri Tioukov, M. Fischetti, Veronica Ferrero, E. Scifoni, Francesco Pennazio, Livio Narici, Osamu Sato, Alessio Sarti, Adele Lauria, Francesco Tommasino, S. Colombi, Giancarlo Sportelli, M. G. Bisogni, A. Stahl, V. Gentile, S. Bianucci, R. Mirabelli, Leonello Servoli, U. Weber, Luca Galli, R. Spighi, Nicola Belcari, M. Marafini, A. Embriaco, C. Sanelli, S. Tommasini, C. Finck, Maria Cristina Montesi, P. Carra, G. Silvestre, A. Alexandrov, R. Hetzel, Silvia Biondi, Giuseppe Battistoni, Giuseppe Giraudo

Charged Particle Therapy (CPT) is a powerful radiotherapy technique for the treatment of deep-seated tumours characterized by a large dose released in the Bragg peak area (corresponding to the tumour region) and a small dose delivered to the surround

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd44c616b20de0d41bf1cf85e859ebfe
http://hdl.handle.net/2108/216503

Ion charge separation with new generation of nuclear emulsion films

Autor: E. Bellinzona, Alberto Mengarelli, M. Villa, E. Fiandrini, F. Raffaelli, Y. Dong, M. Ionica, Esther Ciarrocchi, Marco Francesconi, Nadia Pastrone, Francesco Pennazio, P. Carra, R. Spighi, Alessio Sarti, Antonio Zoccoli, M. Pullia, F. Ferroni, Pisana Placidi, M. Vanstalle, G. Silvestre, M. Emde, C. La Tessa, S. Muraro, L. Narici, M. C. Morone, A.C. Kraan, Marco Durante, R. Arteche Diaz, A. Di Crescenzo, L. Alunni Solestizi, Valeria Rosso, A. Secher, Niccolò Camarlinghi, L. Ramello, Nicola Belcari, E. Iarocci, L. Galli, M. De Simoni, Riccardo Faccini, E. Lopez Torres, C. Finck, Mario Sitta, M. Rovituso, G. De Lellis, M. Marafini, Marco Donetti, Gabriella Sartorelli, V. Gentile, S. Bianucci, Vincenzo Patera, Alberto Clozza, S. Savazzi, M. Fischetti, C. Sanelli, S. M. Valle, A. Sciubba, Osamu Sato, Adele Lauria, E. Scifoni, A. Embriaco, M. Selvi, Ambrosi Giovanni, Maria Cristina Montesi, Francesco Tommasino, Matteo Franchini, Veronica Ferrero, S. Colombi, K. Kanxheri, Christoph Schuy, Uli Weber, Leonello Servoli, A. Alexandrov, Achim Stahl, Stefano Argiro, A. Moggi, R. Mirabelli, Ilaria Mattei, Matteo Morrocchi, M. Garbini, R. Ridolfi, Giacomo Traini, L. Scavarda, Eleuterio Spiriti, Piergiorgio Cerello, V. Lante, Elisa Fiorina, R. Hetzel, Alessandra Pastore, Silvia Biondi, Giuseppe Battistoni, A. Del Guerra, Giuseppe Giraudo, G. Galati, N. Bartosik, Valeri Tioukov, Graziano Bruni, Sandro Tomassini, Giancarlo Sportelli, M. G. Bisogni, A. Schiavi

Publikováno v: Open Phys.
Open Phys., 2019, 17 (1), pp.233-240. ⟨10.1515/phys-2019-0024⟩
Open Physics, Vol 17, Iss 1, Pp 233-240 (2019)
Open physics 17(1), 233-240 (2019). doi:10.1515/phys-2019-0024

In hadron therapy, the accelerated ions, interacting with the body of the patient, cause the fragmentation of both projectile and target nuclei. The fragments interact with the human tissues depositing energy both in the entrance channel and in the v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bacd2349f3cdd6cacb0173a60c4fb85a
https://hal.archives-ouvertes.fr/hal-02154713

On the lateral dose profile of

Autor: A, Embriaco, V E, Bellinzona, A, Fontana, A, Rotondi

Publikováno v: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 40

We investigate the possibility to improve the accuracy of the lateral dose profile forThe full Molière theory for the Coulomb multiple scattering is applied to the case ofThe accuracy of the results compared with Monte Carlo predictions already vali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e3cd81f4038f96b7ddb6685e4be196ea
https://pubmed.ncbi.nlm.nih.gov/28716542

Development and implementation of a non Gaussian model for the lateral dose prediction in a proton therapy treatment planning system

Autor: V. E. Bellinzona

Publikováno v: Journal of Physics: Conference Series. 841:012009

Challenging issues in treatment planning system for hadrontherapy are the accurate and fast calculation of dose distribution, the reduction in memory space required to store the dose kernel of individual pencil beams and the shortening of computation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e3d61a953cc9f22d2dc88bc6dabc2531
https://doi.org/10.1088/1742-6596/841/1/012009