Zobrazeno 1 - 10
of 26
pro vyhledávání: '"E. B. Mechetner"'
Autor:
N. M. Rutkevich, E. B. Mechetner, A. V. Vasil'ev, N. I. Perevodchikova, M. A. Goncharskaya, A. G. Tonevitskii, N. F. Orel
Publikováno v:
Bulletin of Experimental Biology and Medicine. 112:1294-1298
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b0becdbebfd7df0b114282a4d33914c
https://doi.org/10.1007/bf00840610
https://doi.org/10.1007/bf00840610
Autor:
S. S. Kruglov, E. B. Mechetner, E. Yu. Rybalkina, T. N. Zabotina, A. A. Stavrovskaya, Anna G. Turkina, T. P. Stromskaya
Publikováno v:
Biochemistry. Biokhimiia. 73(1)
Imatinib mesylate (imatinib) is a new generation preparation that is now successfully used for treatment of cancer, particularly for chemotherapy of chronic myeloid leukemia (CML). Imatinib inhibits the activity of chimeric kinase BCR-ABL, which is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56008d02f130bc2e1c92e8db824470c
https://pubmed.ncbi.nlm.nih.gov/18294126
https://pubmed.ncbi.nlm.nih.gov/18294126
Autor:
Alexey V. Sorokin, T. N. Zabotina, A. A. Stavrovskaya, Sergey Guryanov, A. V. Vaiman, E. B. Mechetner, Lev P. Ovchinnikov, T. P. Stromskaya, E. Yu. Rybalkina
Publikováno v:
Biochemistry. Biokhimiia. 71(2)
The multifunctional mammalian protein YB-1 is a member of the large DNA- and RNA-binding protein family with an evolutionarily ancient cold-shock domain. YB-1 is involved in multiple DNA- and mRNA-dependent events and regulates gene expression at var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6c60cadb010c8c21d5ba6870baac88
https://pubmed.ncbi.nlm.nih.gov/16489918
https://pubmed.ncbi.nlm.nih.gov/16489918
Autor:
T P, Stromskaia, E Iu, Rybalkina, A G, Turkina, T N, Zabotina, N P, Logacheva, E S, Zakharova, E B, Mechetner, A Iu, Baryshnikov, N D, Khoroshko, A A, Stavrovskaia
Publikováno v:
Terapevticheskii arkhiv. 73(7)
To evaluate the prognostic significance of P-glycoprotein (Pgp) in chronic myeloid leukemia (CML).Functional activity (rhodamine 123 test) and expression of Pgp (binding of UIC2 monoclonal antibodies by cells) were evaluated by flow cytofluorometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f535b6c3db442b7f29a0a1fcc8d186b
https://pubmed.ncbi.nlm.nih.gov/11523404
https://pubmed.ncbi.nlm.nih.gov/11523404
Autor:
P G, Komarov, A A, Shtil, O, Holian, L, Tee, L, Buckingham, E B, Mechetner, I B, Roninson, J S, Coon
Publikováno v:
Oncology research. 10(4)
Treatment-induced secondary drug resistance of tumor cells is a major cause of relapsed disease and therapeutic failure in cancer patients. It has been shown that the expression of the multidrug resistance MDR1/P-glycoprotein gene could be induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c718e087986af6fdc9a278d50f99d67
https://pubmed.ncbi.nlm.nih.gov/9778689
https://pubmed.ncbi.nlm.nih.gov/9778689
Publikováno v:
Experimental hematology. 24(10)
P-glycoprotein (Pgp), a product of the human MDR1 gene, is a member of the ABC superfamily of transporters responsible for the trafficking of biologically active substances across the membrane. In tumors, Pgp is associated with multidrug resistance (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cbff80a4a07deccd68774eb9108f5292
https://pubmed.ncbi.nlm.nih.gov/8765502
https://pubmed.ncbi.nlm.nih.gov/8765502
Autor:
Michael Curcio, G Raghu, E B Mechetner, Philip Caron, P D Roepe, David A. Scheinberg, J H Weisburg
Publikováno v:
The Journal of Experimental Medicine
Multidrug resistance (MDR), which is due, in part, to the overexpression of P-glycoprotein, confers resistance to a variety of natural product chemotherapeutic agents such as daunorubicin, vincristine, and colchicine. RV+ cells are a P-glycoprotein o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797231848485a6f04a033e27438fbb1d
https://pubmed.ncbi.nlm.nih.gov/8676093
https://pubmed.ncbi.nlm.nih.gov/8676093
Autor:
M D, Norris, D, De Graaf, M, Haber, M, Kavallaris, J, Madafiglio, J, Gilbert, E, Kwan, B W, Stewart, E B, Mechetner, A V, Gudkov, I B, Roninson
Publikováno v:
International journal of cancer. 65(5)
Cellular resistance to methotrexate (MTX) is believed to be unaffected by expression of MDR1 P-glycoprotein (Pgp), a pleiotropic efflux pump acting on different hydrophobic compounds that enter cells by passive diffusion. A series of human leukemic C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed371a8fe0a630a5664ef2fbd7efb786
https://pubmed.ncbi.nlm.nih.gov/8598312
https://pubmed.ncbi.nlm.nih.gov/8598312
Publikováno v:
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 46(4-5)
It has been shown previously that erythroblast antigen (AG-EB) is an interspecies antigen expressed on the surface of nucleated red cells and reticulocytes. We have recently produced the monoclonal antibody MAE 15 that reacted specifically with murin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::130bddbeba69c499300807fe91bd8dae
https://pubmed.ncbi.nlm.nih.gov/7894254
https://pubmed.ncbi.nlm.nih.gov/7894254
Autor:
I Iu, Sakharov, E B, Mechetner, E E, Efremov, I E, Stepanova, B V, Shekhonin, O Iu, Pletiushkina
Publikováno v:
Biokhimiia (Moscow, Russia). 56(10)
Monoclonal antibodies (termed as APP.1 and related to subclass IgG1) against seal alkaline phosphatase, have been obtained. APP.1 did not influence the enzymatic activity of alkaline phosphatase. The dissociation constant for the APP.1 interaction wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00b02fc1703deca42af15d9418173893
https://pubmed.ncbi.nlm.nih.gov/1723298
https://pubmed.ncbi.nlm.nih.gov/1723298