Zobrazeno 1 - 10
of 20
pro vyhledávání: '"E. B. Isakova"'
Autor:
A. S. Trenin, S. N. Lavrenov, E. P. Mirchink, E. B. Isakova, O. P. Bychkova, A. Y. Simonov, S. A. Lakatosh, E. A. Tsvigun
Publikováno v:
Антибиотики и Химиотерапия, Vol 62, Iss 1-2, Pp 3-9 (2020)
Trls(1-alkylindol-3-yl)methylium salts that are trls(1-alkylindol-3-yl)methan derivatives with high antibacterial and antifungal activity were obtained through chemical synthesis. These salts were practically not inferior to levolloxacin in their act
Externí odkaz:
https://doaj.org/article/311d3389231d4c81a60d467c1ac06f2e
Autor:
E. P. Mirchink, E. B. Isakova, S. N. Lavrenov, A. Yu. Simonov, V. A. Golibrodo, A. A. Panov, O. P. Bychkova, V. V. Tatarskiy, A. S. Trenin
Publikováno v:
Антибиотики и Химиотерапия, Vol 63, Iss 11-12, Pp 12-17 (2020)
Biological properties of new synthetic triindolylmethylium antibiotics of the triindolylmethane group, including compounds containing a maleimide fragment in the structure, are studied. Their high antibacterial activity in vitro, mainly against gram-
Externí odkaz:
https://doaj.org/article/dda33262d19d4ba4b5b41e4778eea460
Autor:
S. N. Lavrenov, A. Yu. Simonov, A. A. Panov, S. A. Lakatosh, E. B. Isakova, E. A. Tsvigun, O. P. Bychkova, V. V. Tatarskiy, E. S. Ivanova, E. P. Mirchink, A. M. Korolev, A. S'. Trenin
Publikováno v:
Антибиотики и Химиотерапия, Vol 63, Iss 7-8, Pp 4-10 (2020)
Methods for the synthesis of hybrid molecules that combine the structure of a highly active antimicrobial compounds - tris(1-alkylindol-3-yl)methylium as well as 3-(indol-1-yl)maleimides that previously showed activity against some protein kinases ha
Externí odkaz:
https://doaj.org/article/f8e027d1c0eb45bda3590dbd60cfdfea
Autor:
E. E. Bykov, E. P. Mirchink, E. B. Isakova, E. N. Bychkova, E. N. Olsufyeva, A. N. Tevyashova
Publikováno v:
Антибиотики и Химиотерапия, Vol 62, Iss 3-4, Pp 10-17 (2020)
Antibacterial activity of hybrid antibiotics vancomycin-azithromycin (C11, C12-carbonate) and eremomycin-azitromycin (C11, C12-carbonate) was evaluated. Quantum chemical calculations of complexes of hybrid antibiotics with a model tripeptide ligand a
Externí odkaz:
https://doaj.org/article/6c541ce8cc114b3bae93328cdf91c18f
Autor:
S. S. Printsevskaya, A. M. Korolev, Yu. N. Luzikov, E. P. Mirchink, E. B. Isakova, A. N. Tevyashova
Publikováno v:
Антибиотики и Химиотерапия, Vol 63, Iss 1-2, Pp 3-7 (2020)
Benzoxaborole, a structure in medicinal chemistry privileged due to its desirable physicochemical and drug-like properties, was used for the synthesis of azithromycin-benzoxaborole conjugates in which benzoxaborole fragment was attached to the 11-hyd
Externí odkaz:
https://doaj.org/article/da0b20690375481a8d60ace7326b51e1
Autor:
O. V. Efremenkova, B. F. Vasiljeva, V. A. Zenkova, A. M. Korolev, Y. N. Lusikov, T. A. Efimenko, I. A. Malanicheva, E. P. Mirchink, E. B. Isakova, E. N. Bilanenko, O. V. Kamzolkina
Publikováno v:
Антибиотики и Химиотерапия, Vol 60, Iss 11-12, Pp 23-28 (2020)
The fungal strain INA 01108 producing antibiotic substances with broad spectrum of antibacterial activity was isolated from the natural environment. By the morphological characteristics and DNA analysis it was shown to belong to Ascomycetes of Sordar
Externí odkaz:
https://doaj.org/article/1fece19bbfa44dafa94eb1337319b9a7
Autor:
L. M. Krasnopolskaya, M. I. Shuktueva, A. V. Avtonomova, M. S. Yarina, B. R. Dzhavakhyan, E. B. Isakova, V. M. Bukchman
Publikováno v:
Антибиотики и Химиотерапия, Vol 61, Iss 11-12, Pp 16-20 (2020)
The aim of the study was to evaluate antitumor and antioxidant properties of water-soluble polysaccharides from submerged mycelium of Flammulina velutipes grown under optimized conditions. The optimization of the nutrient medium composition allowed t
Externí odkaz:
https://doaj.org/article/4dfa865a51f54e239187fcd7cadac8df
Publikováno v:
Антибиотики и Химиотерапия, Vol 61, Iss 11-12, Pp 3-8 (2020)
A series of hybrid antibiotics on the basis of azithromycin and glycopeptides with the glycopeptide molecule attached via the aminoalkylcarbamoyl spacer to 11-position of the macrolide was synthesized. All the synthesized compounds demonstrated equal
Externí odkaz:
https://doaj.org/article/5449aa1340264aaba95a08f51e983c5a
Autor:
L. M. Krasnopolskaya, M. S. Yarina, A. V. Avtonomova, A. I. Usov, E. B. Isakova, V. M. Bukchman
Publikováno v:
Антибиотики и Химиотерапия, Vol 60, Iss 11-12, Pp 29-34 (2020)
Fractions of water soluble and alkali soluble polysaccharides, as well as fucogalactan, a water soluble polysaccharide, and xylomannan, an alkali soluble polysaccharide, were isolated from the Ganoderma lucidum submerged mycelium. When administered o
Externí odkaz:
https://doaj.org/article/8dae8145833245da9d0a5612ebe5aab5
Publikováno v:
Антибиотики и Химиотерапия, Vol 60, Iss 9-10, Pp 7-11 (2020)
Amidation of the end carboxyl group of eremomycin and vancomycin by pinacolinic 4- or 3-amino methyl phenyl boron acids esters in the presence of the condensing reagent PyBOP resulted in formation of novel carboxamides of the antibiotics (IIIa-VIa).
Externí odkaz:
https://doaj.org/article/28dec7c29e9241d79f6dea09ad8de075