Zobrazeno 1 - 10
of 192
pro vyhledávání: '"E. Angela Murphy"'
Autor:
Thomas D. Cardaci, Brandon N. VanderVeen, Brooke M. Bullard, Sierra J. McDonald, Christian A. Unger, Reilly T. Enos, Daping Fan, Kandy T. Velázquez, Norma Frizzell, Espen E. Spangenburg, E. Angela Murphy
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 124-137 (2024)
Abstract Background More than 650 million people are obese (BMI > 30) worldwide, which increases their risk for several metabolic diseases and cancer. While cachexia and obesity are at opposite ends of the weight spectrum, leading many to suggest a p
Externí odkaz:
https://doaj.org/article/8e58be7d41294061abe0faa6c1ffb64b
Autor:
Qi Zhang, Alexander A. Chumanevich, Ivy Nguyen, Anastasiya A. Chumanevich, Nora Sartawi, Jake Hogan, Minou Khazan, Quinn Harris, Bryson Massey, Ioulia Chatzistamou, Phillip J. Buckhaults, Carolyn E. Banister, Michael Wirth, James R. Hebert, E. Angela Murphy, Lorne J. Hofseth
Publikováno v:
Toxicology Reports, Vol 11, Iss , Pp 221-232 (2023)
The incidence of colorectal cancer (CRC) among young people has been on the rise for the past four decades and its underlying causes are only just starting to be uncovered. Recent studies suggest that consuming ultra-processed foods and pro-inflammat
Externí odkaz:
https://doaj.org/article/c46b816ca39b43b3a837b003e35ee318
Publikováno v:
Cells, Vol 13, Iss 5, p 421 (2024)
Increased production of extracellular matrix is a necessary response to tissue damage and stress. In a normal healing process, the increase in extracellular matrix is transient. In some instances; however, the increase in extracellular matrix can per
Externí odkaz:
https://doaj.org/article/839d7ba5a703408eab2a8823099d164b
Autor:
Sierra J. McDonald, Brooke M. Bullard, Brandon N. VanderVeen, Thomas D. Cardaci, Ioulia Chatzistamou, Daping Fan, E. Angela Murphy
Publikováno v:
Physiological Reports, Vol 11, Iss 19, Pp n/a-n/a (2023)
Abstract It has been suspected that tumor resection surgery itself may accelerate breast cancer (BC) lung metastasis in some patients. Emodin, a natural anthraquinone found in the roots and rhizomes of various plants, exhibits anticancer activity. We
Externí odkaz:
https://doaj.org/article/13cc97b51bdd4dc68a473e6394bf91f0
Autor:
Patrice Cunningham, Christian A. Unger, Emma A. Patton, Akyla Aiken, Alea Browne, Ella James, Ahmed K. Aladhami, Marion C. Hope 3rd, Brandon N. VanderVeen, Thomas D. Cardaci, E. Angela Murphy, Reilly T. Enos, Kandy T. Velázquez
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cachexia, a complex wasting syndrome, significantly affects the quality of life and treatment options for cancer patients. Studies have reported a strong correlation between high platelet count and decreased survival in cachectic individuals. Therefo
Externí odkaz:
https://doaj.org/article/6b8d6ff7ec4b4a95b0692e889b040a1e
Autor:
Brandon N. VanderVeen, Thomas D. Cardaci, Sierra J. McDonald, Sarah S. Madero, Christian A. Unger, Brooke M. Bullard, Reilly T. Enos, Kandy T. Velázquez, Jason L. Kubinak, Daping Fan, E. Angela Murphy
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 1-15 (2022)
Fluorouracil/5-flourouracil (5FU) is a first-line chemotherapy drug for many cancer types; however, its associated toxicities contribute to poor quality of life and reduced dose intensities negatively impacting patient prognosis. While obesity remain
Externí odkaz:
https://doaj.org/article/5a08eb54ec3d41e1976ad2f858905259
Autor:
Christian A. Unger, Ahmed K. Aladhami, Marion C. Hope, Sahar Pourhoseini, Mitzi Nagarkatti, Owen P. McGuinness, E. Angela Murphy, Kandy T. Velázquez, Reilly T. Enos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Epidemiological literature indicates that women are less susceptible to type II diabetes (T2D) than males. The general consensus is that estrogen is protective, whereas its deficiency in post-menopause is associated with adiposity and impair
Externí odkaz:
https://doaj.org/article/16e962fc988748b8b05aabe652d9189e
Autor:
Patrice Cunningham, Emma Patton, Brandon N. VanderVeen, Christian Unger, Ahmed Aladhami, Reilly T. Enos, Sarah Madero, Ioulia Chatzistamou, Daping Fan, E. Angela Murphy, Kandy T. Velázquez
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Quercetin is an organic flavonoid present in several fruits and vegetables. The anti-inflammatory, antiviral, antioxidant, cardio-protective, anti-carcinogenic and neuroprotective properties demonstrated by this dietary supplement
Externí odkaz:
https://doaj.org/article/00975738a9c948089982fd3ae5c20391
Autor:
Sierra J. McDonald, Brandon N. VanderVeen, Brooke M. Bullard, Thomas D. Cardaci, Sarah S. Madero, Ioulia Chatzistamou, Daping Fan, E. Angela Murphy
Publikováno v:
Physiological Reports, Vol 10, Iss 21, Pp n/a-n/a (2022)
Abstract Approximately one‐third of all breast cancer mortality results from metastatic recurrence after initial success of surgery and/or therapy. Although primary tumor removal is widely accepted as beneficial, it has long been suspected that sur
Externí odkaz:
https://doaj.org/article/f560e8a0624a4cebbd96f0ca35631647
Autor:
Junfeng Wang, Quanyi Wang, Yinan Guan, Yulu Sun, Xiaozhi Wang, Kaylie Lively, Yuzhen Wang, Ming Luo, Julian A. Kim, E. Angela Murphy, Yongzhong Yao, Guoshuai Cai, Daping Fan
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 19 (2022)
Evidence suggests that increased microRNA-155 (miR-155) expression in immune cells enhances antitumor immune responses. However, given the reported association of miR-155 with tumorigenesis in various cancers, a debate is provoked on whether miR-155
Externí odkaz:
https://doaj.org/article/7fabbd3ad87c415686178ecd392893d0