Zobrazeno 1 - 10
of 74
pro vyhledávání: '"E. Alteri"'
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 94:419-424
Artemether-lumefantrine (A-L), a new fixed-dose oral antimalarial drug, combines the fast onset of action of artemether (an artemisinin derivative) in terms of parasite clearance with the high cure rate of lumefantrine in the treatment of acute uncom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce23887dd475265eb6439be5b8aafe2b
https://doi.org/10.1016/s0035-9203(00)90126-3
https://doi.org/10.1016/s0035-9203(00)90126-3
Publikováno v:
Antiviral Chemistry and Chemotherapy. 8:54-59
The aim of the study was to determine whether the concentration of CGP 53437 measured in the sera of normal volunteers following oral administration of a single dose, had retained its anti-HIV activity; and whether such results could be of predictive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cd7f1ffed2cf3845096cbbfab20cdf5
https://doi.org/10.1177/095632029700800106
https://doi.org/10.1177/095632029700800106
Autor:
Alexander Faessler, Bernard Poncioni, E Alteri, Marc Lang, Peter Schneider, Thomas Klimkait, Guido Bold, Robert Cozens, Janis K. Lazdins, Johannes Roesel
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:2087-2092
CGP 53437 is a peptidomimetic inhibitor of human immunodeficiency virus type 1 (HIV-1) protease containing a hydroxyethylene isostere. The compound inhibited recombinant HIV-1 protease with a Ki of 0.2 nM. The inhibition constant versus human catheps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b927d54ee932b41ef82136e4b7f45f16
https://doi.org/10.1128/aac.37.10.2087
https://doi.org/10.1128/aac.37.10.2087
Autor:
E Alteri, Alexander Faessler, Marc Lang, M. Gruetter, Guido Bold, Marina Tintelnot-Blomley, Johannes Roesel
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59c0464d85680ffd2b00a76740776e18
https://doi.org/10.1002/chin.199427227
https://doi.org/10.1002/chin.199427227
Autor:
J K Lazdins, T Klimkait, K Woods-Cook, M Walker, E Alteri, D Cox, N Cerletti, R Shipman, G Bilbe, G McMaster
Publikováno v:
The Journal of Immunology. 147:1201-1207
In vitro-differentiated monocytes can be infected with the monocytotropic isolate of HIV-1/ADA. The infection is characterized by formation of giant cells and production of virus that can be found in cell supernatants or cell-associated. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc8b8384f86a102af0451e7964324a24
https://doi.org/10.4049/jimmunol.147.4.1201
https://doi.org/10.4049/jimmunol.147.4.1201
Publikováno v:
Antiviral Research. 13:175-186
An assay for the evaluation of antiviral and immunomodulator potency was developed using pure populations of cultured human monocytes. The assay involved culturing of human monocytes until they were fully susceptible (15-20 days) to lytic infection w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8faba5ab1176bab8998f1375a5b4e7
https://doi.org/10.1016/0166-3542(90)90036-7
https://doi.org/10.1016/0166-3542(90)90036-7
Autor:
Ulrich Hübscher, Peter Schneider, E Alteri, Klaus A. Neftel, Reinhard Hobi, Bernard Poncioni, Kathie Woods-Cook, Maja R. Walker, Janis K. Lazdins
Publikováno v:
Antiviral chemistrychemotherapy. 12(2)
Cephalosporins in aqueous solutions generate degradation products that inhibit in vitro HIV-1 replication in cell lines, as well as in primary cells (lymphocytes and macrophages). This effect is observed at concentrations that do not interfere with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95958ebda76a01d7700442059619aac
https://pubmed.ncbi.nlm.nih.gov/11527042
https://pubmed.ncbi.nlm.nih.gov/11527042
Autor:
Kathie Woods-Cook, Maja R. Walker, E Alteri, Robert Shipman, David Cox, Mcmaster Gary Kent, Nico Cerletti, Graham Bilbe, Janis K. Lazdins, Thomas Klimkait
Publikováno v:
AIDS research and human retroviruses. 8(4)
In vitro exposure of human blood monocyte-derived macrophages to T-cell tropic human immunodeficiency virus (HIV) isolates fails to establish a productive viral infection. Several studies have shown that such preferential HIV-1 replication in T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e045c77b3979ad308ef5ce7506dc86d
https://pubmed.ncbi.nlm.nih.gov/1599757
https://pubmed.ncbi.nlm.nih.gov/1599757
Autor:
Janis K. Lazdins, E Alteri, Kathie Woods-Cook, Graeme Bilbe, Maja R. Walker, Nico Cerletti, R Shipman, Thomas Klimkait, David Cox, Mcmaster Gary Kent
Publikováno v:
Research in virology. 142(2-3)
TGF-β at physiological concentrations, when added to monocyte-derived macrophages following HIV1 infection, has an enhancing effect upon the rate of virus production. This effect is observed with the monocytotropic isolate ADA, as well as with HIV1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7a22ae6044f7e3846b5cbef842a1c3
https://pubmed.ncbi.nlm.nih.gov/1896646
https://pubmed.ncbi.nlm.nih.gov/1896646
Publikováno v:
AIDS research and human retroviruses. 6(10)
Cultured monocyte-derived macrophages were productively infected with human immunodeficiency virus in vitro. Treatment of these cells shortly after infection and several times thereafter with the free form of MTP-PE had an inhibitory effect on virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516c8f07f508bc54b2c8e7ebf8966b8f
https://pubmed.ncbi.nlm.nih.gov/1701314
https://pubmed.ncbi.nlm.nih.gov/1701314