Zobrazeno 1 - 10
of 27
pro vyhledávání: '"E. Allison Green"'
Autor:
E. Allison Green, Anne C. Cooke, Jon D. Piganelli, Sarah J. Richardson, Li Wen, F. Susan Wong
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/ffb8a5003abf4907855312e1f28c5419
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Type 1 diabetes (T1d) results from a sustained autoreactive T and B cell response towards insulin-producing β cells in the islets of Langerhans. The autoreactive nature of the condition has led to many investigations addressing the genetic or cellul
Externí odkaz:
https://doaj.org/article/8ddec431866b49e3bf36f3d94fe73ec2
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Type 1 diabetes (T1D) results from a coordinated autoimmune attack of insulin producing beta cells in the pancreas by the innate and adaptive immune systems, beta cell death being predominantly T cell-mediated. In addition to T cells, peripheral B ce
Externí odkaz:
https://doaj.org/article/69966b538b8e4bafbffb3f28f54dd3fe
Autor:
E. Allison Green
Publikováno v:
European Medical Journal Diabetes, Vol 3, Iss 1, Pp 96-102 (2015)
Immunobiological interventions are proving to be an exciting new area for mobilising the immune response towards certain tumours. In contrast, classical immunotherapeutic interventions aimed at dampening the autoimmune response to host tissue have be
Externí odkaz:
https://doaj.org/article/4a5af0d760d642739bfeac7e842fd704
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Type 1 diabetes (T1d) results from a sustained autoreactive T and B cell response towards insulin-producing β cells in the islets of Langerhans. The autoreactive nature of the condition has led to many investigations addressing the genetic or cellul
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Type 1 diabetes (T1D) results from a coordinated autoimmune attack of insulin producing beta cells in the pancreas by the innate and adaptive immune systems, beta cell death being predominantly T cell-mediated. In addition to T cells, peripheral B ce
Autor:
Manu Chhabra, E. Allison Green
Publikováno v:
How to Complete a PhD in the Medical and Clinical Sciences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c622529e2ddec45e2088ce5b80f5d818
https://doi.org/10.1002/9781119189657.ch9
https://doi.org/10.1002/9781119189657.ch9
Publikováno v:
The Journal of Immunology. 186:2543-2551
Effective therapies that prevent chronic inflammation from developing into type 1 diabetes remain elusive. In this study, we show that expression of TGF-β for just 1 wk in inflamed islets of NOD mice significantly delays diabetes development. Time c
Autor:
E. Allison Green, Philip J Spence
Publikováno v:
Proceedings of the National Academy of Sciences. 105:973-978
Foxp3 + regulatory T cells develop in the thymus and are essential for maintaining peripheral tolerance to self tissues. We report the critical requirement for CD154 up-regulation specifically on, and during the thymic development of, Foxp3 + regulat
Publikováno v:
Proceedings of the National Academy of Sciences. 101:4572-4577
CD4+CD25+regulatory T cells are essential in the protection from organ-specific autoimmune diseases. In the pancreas, they inhibit actions of autoreactive T cells and thereby prevent diabetes progression. The signals that control the generation, the