Zobrazeno 1 - 10
of 116
pro vyhledávání: '"E. Aktepe"'
Autor:
Maya Shemesh, Turgut E. Aktepe, Joshua M. Deerain, Julie L. McAuley, Michelle D. Audsley, Cassandra T. David, Damian F. J. Purcell, Victoria Urin, Rune Hartmann, Gregory W. Moseley, Jason M. Mackenzie, Gideon Schreiber, Daniel Harari
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/5b8a003f94a64502afa9a906acb83f64
Autor:
Maya Shemesh, Turgut E Aktepe, Joshua M Deerain, Julie L McAuley, Michelle D Audsley, Cassandra T David, Damian F J Purcell, Victoria Urin, Rune Hartmann, Gregory W Moseley, Jason M Mackenzie, Gideon Schreiber, Daniel Harari
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009800 (2021)
Type I Interferons (IFN-Is) are a family of cytokines which play a major role in inhibiting viral infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I response. Here we tested the impact of expression of 27 differe
Externí odkaz:
https://doaj.org/article/a1d78fad6c5f4fa381f8684888d7c0c1
Autor:
Julie L. McAuley, Joshua M. Deerain, William Hammersla, Turgut E. Aktepe, Damian F. J. Purcell, Jason M. Mackenzie
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
To restrict the potential transmission and infectivity of SARS-CoV-2, the use of liquid chalk has been a requirement in an active gym setting. However, its effectiveness has not been scientifically proven.
Externí odkaz:
https://doaj.org/article/553221789dec406c8bed3daa947fa2f8
Autor:
Andrea Mikulasova, Leah K. Gillespie, Rebecca L. Ambrose, Turgut E. Aktepe, Alice M. Trenerry, Susann Liebscher, Jason M. Mackenzie
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Flavivirus replication is intimately associated with re-organized cellular membranes. These virus-induced changes in membrane architecture form three distinct membranous “organelles” that have specific functions during the flavivirus life cycle.
Externí odkaz:
https://doaj.org/article/a23da46d23b243618540852c794bfe08
Publikováno v:
Cell Reports, Vol 21, Iss 6, Pp 1639-1654 (2017)
Summary: Flaviviruses are enveloped, positive-sensed single-stranded RNA viruses that remodel host membranes, incorporating both viral and host factors facilitating viral replication. In this study, we identified a key role for the membrane-bending h
Externí odkaz:
https://doaj.org/article/e2a4d7d0d8ac409b859d7f5c9dfd59fe
Autor:
Svenja Fritzlar, Turgut E. Aktepe, Yi-Wei Chao, Nathan D. Kenney, Michael R. McAllaster, Craig B. Wilen, Peter A. White, Jason M. Mackenzie
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT The integrated stress response (ISR) is a cellular response system activated upon different types of stresses, including viral infection, to restore cellular homeostasis. However, many viruses manipulate this response for their own advantage
Externí odkaz:
https://doaj.org/article/db7b8cd4f9884341ab531a32a8b1cc2e
Autor:
Marios Koutsakos, Hamish E. G. McWilliam, Turgut E. Aktepe, Svenja Fritzlar, Patricia T. Illing, Nicole A. Mifsud, Anthony W. Purcell, Steve Rockman, Patrick C. Reading, Julian P. Vivian, Jamie Rossjohn, Andrew G. Brooks, Jason M. Mackenzie, Justine D. Mintern, Jose A. Villadangos, Thi H. O. Nguyen, Katherine Kedzierska
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Manipulation of the MHC-I presentation pathway, and thus limiting MHC-I cell surface expression, is used by many viruses to evade immune recognition. In particular, downregulation of MHC-I molecules at the cell surface can reduce the ability of CD8+
Externí odkaz:
https://doaj.org/article/ce4b05102b824b13a22f34b603ff78dc
Autor:
Turgut E Aktepe, Joshua M Deerain, Jennifer L. Hyde, Svenja Fritzlar, Jaclyn Pearson, Peter A. White, Jason M. Mackenzie
Norovirus infection is characterised by a rapid onset of disease and the development of debilitating symptoms including projectile vomiting and diffuse diarrhoea. Vaccines and antivirals are sorely lacking and developments in these areas are hampered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1294831b03fdceda036b066e173e255
https://doi.org/10.1101/2023.04.23.537759
https://doi.org/10.1101/2023.04.23.537759
Autor:
Susann Liebscher, Rebecca L Ambrose, Turgut E Aktepe, Andrea Mikulasova, Julia E Prier, Leah K Gillespie, Adam J Lopez-Denman, Thusitha W T Rupasinghe, Dedreia Tull, Malcolm J McConville, Jason M Mackenzie
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1007029 (2018)
Positive-sense RNA virus intracellular replication is intimately associated with membrane platforms that are derived from host organelles and comprised of distinct lipid composition. For flaviviruses, such as West Nile virus strain Kunjin virus (WNVK
Externí odkaz:
https://doaj.org/article/8dd0692a726149698f1db45e8f5456da
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