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pro vyhledávání: '"E. Aisha Freeman"'
Autor:
Karen M. Dunkerley, Yiming Xiao, Jacob D. Aguirre, Lars Konermann, Helen Walden, Viduth K. Chaugule, Gary S. Shaw, Tara E.C. Condos, Kathryn R. Barber, E. Aisha Freeman
Publikováno v:
The EMBO Journal
The E3 ligase parkin ubiquitinates outer mitochondrial membrane\ud proteins during oxidative stress and is linked to early-onset\ud Parkinson’s disease. Parkin is autoinhibited but is activated by the\ud kinase PINK1 that phosphorylates ubiquitin l