Zobrazeno 1 - 10
of 108
pro vyhledávání: '"E. Ahlskog"'
Autor:
Demetrius M. Maraganore, Bryan T. Klassen, Emily Owens, Anhar Hassan, J. E. Ahlskog, Keith A. Josephs, Joseph Y. Matsumoto, Rodolfo Savica, James H. Bower
Publikováno v:
Journal of Neurology. 263:2419-2423
Gait freezing as a presenting and relatively restricted condition is uncommon but a distinctive disorder. This entity was initially defined as "pure akinesia with gait freezing", and later a neuropathological substrate of progressive supranuclear pal
Autor:
Michael G. Heckman, Sruti Rayaprolu, Ryan J. Uitti, Jay A. van Gerpen, Daniel J. Serie, Owen A. Ross, J. E. Ahlskog, Anhar Hassan, Michael S. Okun, Zbigniew K. Wszolek
Publikováno v:
Parkinsonism & Related Disorders. 22:102-105
Introduction Dopamine and glutamate are crucial neurotransmitters in Parkinson disease (PD). While recent large meta-analyses reported that genetic variation of dopamine (DRD2, DRD3) and glutamine (NMDA, GRIN2B) neurotransmitter receptors was not ass
Autor:
Heather M. Clark, J. E. Ahlskog, Jennifer L. Whitwell, Eric J. Sorenson, Joseph R. Duffy, Keith A. Josephs
Publikováno v:
European Journal of Neurology. 21:368-376
To describe speech, neurological and imaging characteristics of a series of patients presenting with progressive spastic dysarthria as the first and predominant sign of a presumed neurodegenerative disease.Participants were 25 patients with spastic d
Autor:
B. F. Boeve, Jennifer L. Whitwell, Stephen D. Weigand, Keith A. Josephs, J. E. Ahlskog, C. R. Jack, R. C. Petersen, Jeffrey L. Gunter, Joseph E. Parisi, Dennis W. Dickson
Publikováno v:
European Journal of Neurology. 20:1417-1422
Background Midbrain atrophy is a characteristic feature of progressive supranuclear palsy (PSP), although it is unclear whether it is associated with the PSP syndrome (PSPS) or PSP pathology. We aimed to determine whether midbrain atrophy is a useful
Autor:
Keith A. Josephs, Bryan T. Klassen, Robert D. Fealey, Emily Owens, Anhar Hassan, Karl N. Krecke, J. E. Ahlskog, James H. Bower, Joseph Y. Matsumoto
Publikováno v:
Parkinsonismrelated disorders. 28
The diagnosis of progressive supranuclear palsy is often challenging early in the course of the disease, when clinical signs of the condition may be less apparent and patients do not clearly meet diagnostic criteria. In this study, we examine a poten
Publikováno v:
European Journal of Neurology. 19:764-768
Background and purpose: Severe multiple sclerosis (MS) tremor causes disability poorly responsive to medication. Deep brain stimulation (DBS) or thalamotomy can suppress tremor, but long-term outcomes are unclear. Methods: Nine patients with MS tremo
Autor:
James H. Bower, Keith A. Josephs, J. E. Ahlskog, Neeraj Kumar, Joseph Y. Matsumoto, Anhar Hassan, Robert D. Fealey
Publikováno v:
Parkinsonism & Related Disorders. 17:260-264
Background Compulsive behaviors provoked by dopamine agonists often go undetected in clinical series, especially if not specifically inquired about. Aim To determine the frequency of compulsive behaviors in a Parkinson’s disease (PD) clinic where a
Autor:
Joseph E. Parisi, B. F. Boeve, D. S. Knopman, M. L. Senjem, J. E. Ahlskog, Jennifer L. Whitwell, R. C. Petersen, Daniel A. Drubach, K. A. Josephs, C. R. Jack, Dennis W. Dickson
Publikováno v:
Neurology. 75:1879-1887
Background: Corticobasal syndrome (CBS) can be associated with different underlying pathologies that are difficult to predict based on clinical presentation. The aim of this study was to determine whether patterns of atrophy on imaging could be usefu
Autor:
James H. Bower, Rodolfo Savica, A. E. Bharucha, Brandon R. Grossardt, Demetrius M. Maraganore, J. M. Carlin, Walter A. Rocca, J. E. Ahlskog
Publikováno v:
Neurology. 73:1752-1758
Objective: Parkinson disease (PD) may affect the autonomic nervous system and may cause constipation; however, few studies have explored constipation preceding the motor onset of PD. We investigated constipation preceding PD using a case-control stud
Autor:
Demetrius M. Maraganore, Brandon R. Grossardt, Walter A. Rocca, J. E. Ahlskog, M. De Andrade, James H. Bower, Lee J. Melton
Publikováno v:
Neurology. 69:1074-1083
There is increasing laboratory evidence that estrogen has neuroprotective effects that may include improved synapse formation, increased cerebral blood flow and glucose metabolism, antioxidant activity, and reduced deposition of β-amyloid in the bra