Zobrazeno 1 - 10
of 461
pro vyhledávání: '"E. Adair"'
Autor:
Patricia O'Campo, Rosane Nisenbaum, Anne G Crocker, Tonia Nicholls, Faith Eiboff, Carol E Adair
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0277074 (2023)
ObjectiveThere is scant research on the effectiveness of permanent supportive housing for homeless women with mental illness. This study examines the effectiveness of Housing First with an unprecedentedly large sample of homeless women from five Cana
Externí odkaz:
https://doaj.org/article/e36e7e4986e740d78ebd2f11c2e67829
Autor:
Brenda J. Seymour, Swati Singh, Hannah M. Certo, Karen Sommer, Blythe D. Sather, Socheath Khim, Courtnee Clough, Malika Hale, Joseph Pangallo, Byoung Y. Ryu, Iram F. Khan, Jennifer E. Adair, David J. Rawlings
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 635-651 (2021)
X-linked agammaglobulinemia (XLA) is an immune disorder caused by mutations in Bruton’s tyrosine kinase (BTK). BTK is expressed in B and myeloid cells, and its deficiency results in a lack of mature B cells and protective antibodies. We previously
Externí odkaz:
https://doaj.org/article/4469c8d686fc425a84ca48e687ffdce5
Autor:
Stefan Radtke, Dnyanada Pande, Margaret Cui, Anai M. Perez, Yan-Yi Chan, Mark Enstrom, Stefanie Schmuck, Andrew Berger, Tom Eunson, Jennifer E. Adair, Hans-Peter Kiem
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 679-691 (2020)
Hematopoietic stem cell (HSC) gene therapy has the potential to cure many genetic, malignant, and infectious diseases. We have shown in a nonhuman primate gene therapy and transplantation model that the CD34+CD90+ cell fraction was exclusively respon
Externí odkaz:
https://doaj.org/article/261752fffa134004b8b8adfca84f2e43
Autor:
Jennifer E. Adair, Mark R. Enstrom, Kevin G. Haworth, Lauren E. Schefter, Reza Shahbazi, Daniel R. Humphrys, Shaina Porter, Kenric Tam, Matthew H. Porteus, Hans-Peter Kiem
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 796-809 (2020)
In vivo tracking of retrovirus-tagged blood stem and progenitor cells is used to study hematopoiesis. Two techniques are used most frequently: sequencing the locus of retrovirus insertion, termed integration site analysis, or retrovirus DNA barcode s
Externí odkaz:
https://doaj.org/article/2ca949df16b442a8a0654694a05cea59
Autor:
Alyssa Sheih, Valentin Voillet, Laïla-Aïcha Hanafi, Hannah A. DeBerg, Masanao Yajima, Reed Hawkins, Vivian Gersuk, Stanley R. Riddell, David G. Maloney, Martin E. Wohlfahrt, Dnyanada Pande, Mark R. Enstrom, Hans-Peter Kiem, Jennifer E. Adair, Raphaël Gottardo, Peter S. Linsley, Cameron J. Turtle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Understanding factors that impact CAR T cell expansion in the clinic is crucial to improving its therapeutic success. Here the authors document heterogeneity in the clonal dynamics of CAR-T cells by tracking individual clones using the endogenous TCR
Externí odkaz:
https://doaj.org/article/9a5dfb14385d4c6ba59269c0303b6190
Autor:
Christopher W. Peterson, Jennifer E. Adair, Martin E. Wohlfahrt, Claire Deleage, Stefan Radtke, Blake Rust, Krystin K. Norman, Zachary K. Norgaard, Lauren E. Schefter, Gabriella M. Sghia-Hughes, Andrea Repetto, Audrey Baldessari, Robert D. Murnane, Jacob D. Estes, Hans-Peter Kiem
Publikováno v:
Stem Cell Reports, Vol 13, Iss 1, Pp 91-104 (2019)
Summary: Myeloid-differentiated hematopoietic stem cells (HSCs) have contributed to a number of novel treatment approaches for lysosomal storage diseases of the central nervous system (CNS), and may also be applied to patients infected with HIV. We q
Externí odkaz:
https://doaj.org/article/4ca7ae8953f54b429b0918e4417bc4a9
Autor:
Kiran Pohar Manhas, Shawn X. Dodd, Stacey Page, Nicole Letourneau, Carol E. Adair, Xinjie Cui, Suzanne C. Tough
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Mandates abound to share publicly-funded research data for reuse, while data platforms continue to emerge to facilitate such reuse. Birth cohorts (BC) involve longitudinal designs, significant sample sizes and rich and deep datase
Externí odkaz:
https://doaj.org/article/6f58a115e71b4702aa4c5ee8dc54f7f3
Autor:
Jino Distasio, Carol E. Adair, Stephen Hwang, Aynslie Hinds, Brianna C. Kopp, Tim Aubry, Julian Somers, Ashley Lemieux, James Dunn, Scott Veldhuizen, Andrew F. Kaufman
Publikováno v:
Wellbeing, Space and Society, Vol 2, Iss , Pp 100008- (2021)
We developed, tested, and operationalized a comprehensive objective measurement tool, the Observer-rated Housing Quality Scale (OHQS), to assess housing unit, building, and neighbourhood characteristics in a large trial of Housing First (HF) in 5 Can
Externí odkaz:
https://doaj.org/article/ff25e1bc50354f7e858006db4ee6187a
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 5, Iss 1 (2020)
BackgroundThe use of tranexamic acid (TXA) has become increasingly prevalent for hemorrhage prevention in military trauma patients due to its known survival benefits. There is concern of increased venous thromboembolism (VTE) subsequent to receiving
Externí odkaz:
https://doaj.org/article/4b358a5e428f4749bdceaab5d2838d5c
Autor:
Hamenth Kumar Palani, Arun Kumar Arunachalam, Mohammed Yasar, Arvind Venkatraman, Uday Kulkarni, Sharon Anbumalar Lionel, Sushil Selvarajan, Anu Korula, Aby Abraham, Biju George, Jennifer E. Adair, Rimas Orentas, Boro Dropulic, Vikram Mathews
Publikováno v:
Bone Marrow Transplantation. 58:160-167
Chimeric Antigen Receptor (CAR) T cell therapy is an accepted standard of care for relapsed/refractory B cell malignancies. However, the high cost of existing industry-driven centralized production makes this therapy unaffordable in low and middle-in