Zobrazeno 1 - 10
of 24
pro vyhledávání: '"E. A. Timina"'
Publikováno v:
Bulletin of Experimental Biology and Medicine. 143:64-67
Parameters of peripheral blood in female rats remained practically unchanged at late terms after single treatment with antitumor drug etoposise. Pregnancy was accompanied by the development of reversible regeneration anemia. Proliferative activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff331f0f0fd92fc09a9f7212c80bd1fb
https://doi.org/10.1007/s10517-007-0083-1
https://doi.org/10.1007/s10517-007-0083-1
Publikováno v:
Bulletin of Experimental Biology and Medicine. 127:33-36
The morphological signs of apoptosis in the bone-marrow cells and thymocytes, indices of cellularity in these organs and in peripheral blood and the absolute number of committed bone marrow cells-precursors have been studied on CBA mice injected with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21cda14a955a132e652589ce80ea6160
https://doi.org/10.1007/bf02432794
https://doi.org/10.1007/bf02432794
Autor:
E. A. Timina, Yu. A. Shchemerova, A. V. Pakhomova, T. G. Borovskaya, V. E. Gol’dberg, A. V. Perova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 143:614-616
The possibility of reducing the ovariotoxicity of antitumor drug etoposide with buserelin, a hypothalamic regulator of pituitary function, was studied in female Wistar rats. Quantitative analysis of ovarian structural and functional elements on seria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cdf0b0553adbae83113c90e85b8fbe
https://doi.org/10.1007/s10517-007-0196-6
https://doi.org/10.1007/s10517-007-0196-6
Publikováno v:
Bulletin of Experimental Biology and Medicine. 143:61-63
Antitumor drug paclitaxel administered in MTD to female rats 1, 3, and 6 months before mating with intact males had a toxic effect on the progeny. We observed increased anteand postnatal mortality, decelerated physical development, low rate of format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88fe9562c2659e8a3e856d78c40358bf
https://doi.org/10.1007/s10517-007-0082-2
https://doi.org/10.1007/s10517-007-0082-2
Publikováno v:
Bulletin of Experimental Biology and Medicine. 143:18-20
The morphology and function of the ovaries at the early and late terms after single intravenous injection of paclitaxel in the maximum tolerated dose (MTD) were studied in female Wistar rats. Evaluation of the structural and functional elements of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c40fc10393f344abaace1fe9d566db4
https://doi.org/10.1007/s10517-007-0072-4
https://doi.org/10.1007/s10517-007-0072-4
Publikováno v:
Bulletin of Experimental Biology and Medicine. 141:645-647
Morphological and functional state of the ovaries in female Wistar rats was assessed in the early and late periods after administration of antitumor drug vepesid in a single maximum tolerated dose. In the early period, the drug pronouncedly decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9623cace9dbff2b5cebbc79f0de0616
https://doi.org/10.1007/s10517-006-0242-9
https://doi.org/10.1007/s10517-006-0242-9
Publikováno v:
Bulletin of Experimental Biology and Medicine. 124:1194-1197
Stable morphological changes and disorders of spermatogenesis develop in the testicles of Wistar rats during 30 days after a single injection of vepeside in the maximum tolerance dose. By the end of experiment the morphology of the testicles graduall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7499dda1413dd0a3a173224b526ac10b
https://doi.org/10.1007/bf02445117
https://doi.org/10.1007/bf02445117
Autor:
E. A. Timina, M. V. Zavjalova, V. M. Perelmuter, S. V. Vtorushin, T. G. Borovskaja, T. I. Fomina
Publikováno v:
Bulletin of experimental biology and medicine. 144(5)
Intravenous injection of antitumor drug etoposide in the maximum tolerated dose was followed by the development of breast cancer in 38.1% female Wistar rats and 6.7% female outbred mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca1976f1a474edff7c1d74b66b351e9
https://pubmed.ncbi.nlm.nih.gov/18683507
https://pubmed.ncbi.nlm.nih.gov/18683507
Autor:
G V, Karpov, T I, Fomina, O L, Voronova, E V, Abramova, E A, Timina, T Iu, Lamzina, L A, Ermolaeva, A V, Perova
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 70(4)
Paclitaxel (single intravenous injection in a maximum tolerated dose of 4.6 mg/kg) to white outbred rats causes bone marrow hypoplasia, increased granulocyte and erythroid cell mitosis (metaphase-anaphase transition), and moderate pancytopenia develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b3a8e40b6b0e0c8512fcff921415a81
https://pubmed.ncbi.nlm.nih.gov/18078042
https://pubmed.ncbi.nlm.nih.gov/18078042
Autor:
V. E. Gol’dberg, Yu. A. Shchemerova, A. V. Perova, E. A. Timina, M. E. Poluektova, T. G. Borovskaya
Publikováno v:
Bulletin of experimental biology and medicine. 140(3)
Experiments on adult rats showed that a single intravenous injection of antitumor drug vepeside in a MTD (maximum tolerable dose) reduced the reproductive status during periods corresponding to exposure of mature sex cells, spermatocytes, and spermat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c370cef982fd819fd48837fa29bc3d7
https://pubmed.ncbi.nlm.nih.gov/16307047
https://pubmed.ncbi.nlm.nih.gov/16307047