Zobrazeno 1 - 10
of 47
pro vyhledávání: '"E. A. Sotaniemi"'
Publikováno v:
British Journal of Clinical Pharmacology. 36:339-343
1. Casodex is a novel non-steroidal antiandrogen being developed for the treatment of prostatic cancer. The antiandrogenic activity is predominantly in the R(-) enantiomer with little, if any, activity in the S(+) enantiomer. 2. The pharmacokinetics
Publikováno v:
Therapie. 51(4)
The effect of age on human liver drug-metabolizing ability was investigated by using probe drugs, metabolized by specific isozymes in liver, as an index. Formation of monoethylglycinexylide (MEGX) after i.v. infusion of lignocaine (1 mg/kg), metaboli
Publikováno v:
Diabetes care. 18(10)
To investigate the effect of ginseng on newly diagnosed non-insulin-dependent diabetes mellitus (NIDDM) patients.In this double-blind placebo-controlled study, 36 NIDDM patients were treated for 8 weeks with ginseng (100 or 200 mg) or placebo. Effica
Publikováno v:
International journal of clinical pharmacology, therapy, and toxicology. 30(11)
Publikováno v:
Research communications in chemical pathology and pharmacology. 74(1)
The present study demonstrates that MPA treatment may alter liver ultrastructure in rats. This was seen as a slight cytoplasmic vacuolization in light microscopy. In electron microscopy the most striking findings were the increase in the size of hepa
Autor:
A. J. Arranto, E. A. Sotaniemi
Publikováno v:
Scandinavian Journal of Gastroenterology. 16:853-863
Alpha-methyldopa-induced histologic alterations were investigated in 21 patients with hepatic injury after short- and long-term exposure. Seven patients developed liver injury within 6 months and 24 after several years (mean, 5 years) of exposure. Hi
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 43:671-675
Publikováno v:
Diabetes. 34:911-916
Publikováno v:
Diabetes. 29:788-794
Publikováno v:
Biological Trace Element Research. 8:113-121
This study evaluated selenium status in relation to lipid peroxidation, liver microsomal function, and serum lipids in humans. Serum selenium concentration, glutathione peroxidase (GSH-Px) activity, liver microsomal enzyme activity, assessed by plasm