Zobrazeno 1 - 10
of 13
pro vyhledávání: '"E. A. M. Festen"'
Autor:
Floris Imhann, K. J. Van der Velde, R. Barbieri, R. Alberts, M. D. Voskuil, A. Vich Vila, V. Collij, L. M. Spekhorst, K. W. J. Van der Sloot, V. Peters, H. M. Van Dullemen, M. C. Visschedijk, E. A. M. Festen, M. A. Swertz, G. Dijkstra, R. K. Weersma
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Inflammatory bowel disease (IBD) is a chronic complex disease of the gastrointestinal tract. Patients with IBD can experience a wide range of symptoms, but the pathophysiological mechanisms that cause these individual differences
Externí odkaz:
https://doaj.org/article/446b5954d4da4d6a976d67efa2dcc134
Autor:
Floris Imhann, K. J. Van der Velde, R. Barbieri, R. Alberts, M. D. Voskuil, A. Vich Vila, V. Collij, L. M. Spekhorst, K. W. J. Van der Sloot, V. Peters, H. M. Van Dullemen, M. C. Visschedijk, E. A. M. Festen, M. A. Swertz, G. Dijkstra, R. K. Weersma
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-1 (2019)
Following publication of the original article [1], the authors
Externí odkaz:
https://doaj.org/article/43cbd0a8af8e44cb8c1c1d9abe5c0cab
Autor:
A Bourgonje, S Hu, R Gacesa, B H Jansen, J R Björk, A Bangma, I J Hidding, H M van Dullemen, M C Visschedijk, K N Faber, G Dijkstra, H J M Harmsen, E A M Festen, A Vich Vila, L M Spekhorst, R K Weersma
Publikováno v:
Journal of Crohn's and Colitis. 17:i113-i115
Background Host intestinal immune gene signatures and microbial dysregulations expose potential mechanisms in the pathogenesis of inflammatory bowel diseases (IBD). Profiling of mucosa-attached microbiota allows the understanding of locally present m
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208922 (2018)
IntroductionTNF-α-neutralizing antibodies, such as infliximab (IFX) and adalimumab (ADA), are effective in the treatment of inflammatory bowel diseases (IBD), but they are expensive and become ineffective when patients develop anti-IFX or anti-ADA a
Externí odkaz:
https://doaj.org/article/ee266d4620e84cd8b0bd9a322485b04a
Autor:
T Straatmijer, M Visschedijk, A de Vries, F Hoentjen, A A van Bodegraven, A G L Bodelier, N K H de Boer, G Dijkstra, E A M Festen, C Horjus, J M Jansen, B Jharap, W Mares, B Oldenburg, C Y Ponsioen, T E H Romkens, N Srivastava, M M van der Voorn, R L West, J C van der Woude, M D J Wolvers, M Pierik, A E van der Meulen, M Duijvestein
Publikováno v:
Journal of Crohn's and Colitis. 16:i118-i120
Background Clinicians face difficulty in positioning biologics and JAK inhibitors in anti-TNF refractory ulcerative colitis (UC) patients. Head-to-head trials comparing the efficacy of vedolizumab and tofacitinib in UC patients are lacking. We aimed
Autor:
A R Bourgonje, S Andreu-Sánchez, T Vogl, S Hu, A Vich Vila, S Leviatan, A Kurilshikov, S Klompus, I N Kalka, H M van Dullemen, A Weinberger, M C Visschedijk, E A M Festen, K N Faber, C Wijmenga, G Dijkstra, E Segal, J Fu, A Zhernakova, R K Weersma
Publikováno v:
Journal of Crohn's and Colitis. 16:i100-i102
Background Patients with IBD show distinct antibody responses, particularly against microbiota. However, a comprehensive overview of the antibody epitope repertoire in IBD is lacking. Here, we characterized serum antibody responses in patients with I
Autor:
A R Bourgonje, S Hu, L M Spekhorst, D V Zhernakova, A Vich Vila, Y Li, M D Voskuil, L A van Berkel, B Bley Folly, M Charrout, A Mahfouz, M J T Reinders, J I P van Heck, L A B Joosten, M C Visschedijk, H M van Dullemen, K N Faber, J N Samsom, E A M Festen, G Dijkstra, R K Weersma
Publikováno v:
Journal of Crohn's and Colitis. 15:S036-S039
Background Protein profiling in patients with inflammatory bowel diseases (IBD) for diagnostic and therapeutic purposes is underexplored. Assessment of interactions between genetics and the plasma proteome could lead to identification of novel diseas
Autor:
M Sorokina Alexdóttir, A R Bourgonje, M A Karsdal, A C Bay-Jensen, M Pehrsson, R Loveikyte, H M van Dullemen, M C Visschedijk, E A M Festen, R K Weersma, K N Faber, G Dijkstra, M Joachim H
Publikováno v:
Journal of Crohn's and Colitis. 16:i468-i469
Background Crohn‘s disease (CD) is a form of inflammatory bowel disease characterized by high infiltration of immune cells into the intestinal tissue, resulting in increased proteolytic mediated extracellular matrix (ECM) remodeling. Disease manage
Autor:
A R Bourgonje, S J Wichers, S Hu, H M van Dullemen, M C Visschedijk, K N Faber, E A M Festen, G Dijkstra, J N Samsom, R K Weersma, L M Spekhorst
Publikováno v:
Journal of Crohn's and Colitis. 16:i284-i285
Background Fatigue is a common and clinically challenging symptom in patients with inflammatory bowel diseases (IBD). While fatigue occurs most often in patients with active disease, up to 50% of patients with quiescent disease still report significa
Autor:
A R Bourgonje, M Alexdottir, R Loveikyte, M Pehrsson, A C Bay-Jensen, H M van Dullemen, M C Visschedijk, E A M Festen, R K Weersma, M A Karsdal, K N Faber, J H Mortensen, G Dijkstra
Publikováno v:
Journal of Crohn's and Colitis. 16:i214-i215
Background Crohn’s disease (CD) and ulcerative colitis (UC) are characterized by intestinal inflammation and increased extracellular matrix (ECM) remodeling, which are key pathophysiological mechanisms in patients with IBD and highly related to muc